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- W4225657695 abstract "Neurons that signal the angular velocity of head movements (AHV cells) are important for processing visual and spatial information. However, it has been challenging to isolate the sensory modality that drives them and to map their cortical distribution. To address this, we develop a method that enables rotating awake, head-fixed mice under a two-photon microscope in a visual environment. Starting in layer 2/3 of the retrosplenial cortex, a key area for vision and navigation, we find that 10% of neurons report angular head velocity (AHV). Their tuning properties depend on vestibular input with a smaller contribution of vision at lower speeds. Mapping the spatial extent, we find AHV cells in all cortical areas that we explored, including motor, somatosensory, visual, and posterior parietal cortex. Notably, the vestibular and visual contributions to AHV are area dependent. Thus, many cortical circuits have access to AHV, enabling a diverse integration with sensorimotor and cognitive information." @default.
- W4225657695 created "2022-05-05" @default.
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- W4225657695 date "2021-12-01" @default.
- W4225657695 modified "2023-10-17" @default.
- W4225657695 title "Mapping vestibular and visual contributions to angular head velocity tuning in the cortex" @default.
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- W4225657695 doi "https://doi.org/10.1016/j.celrep.2021.110134" @default.
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