FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225658840> ?p ?o ?g. }

• W4225658840 endingPage "683" @default.
• W4225658840 startingPage "673" @default.
• W4225658840 abstract "Chronic hepatitis B (CHB) and metabolic associated fatty liver disease (MAFLD) are both important public health problems. The effect of concomitant MAFLD on patients with CHB is still unclear. This study aimed to explore the influence of MAFLD on liver fibrosis and inflammation in CHB patients with different hepatitis B e antigen (HBeAg) status.We retrospectively collected the clinical data of 399 treatment-naïve CHB patients who underwent liver biopsy. All patients were divided into two groups (HBeAg± group). Logistic regression analysis was used to identify factors associated with liver inflammatory activity and significant fibrosis in patients with CHB. Multivariable logistic regressions were repeated in subgroups stratified by HBeAg status.In patients with CHB, MAFLD was independently associated with a risk of moderate-to-severe liver activity and significant fibrosis (P <0.05). In the HBeAg-negative group, patients with MAFLD had significantly higher levels of alanine aminotransferase (ALT) (P <0.05) and more severe liver inflammatory activity and fibrosis (P <0.05) compared to those without MAFLD. MAFLD was independently associated with a risk of moderate-to-severe liver activity (A ≥3: OR 3.97, 95% CI 1.71-9.22, P =0.001) and significant fibrosis (F ≥2: OR 2.02, 95% CI 1.09-3.73, P =0.026). In the HBeAg-positive group, MAFLD was found to be independently associated with moderate-to-severe liver activity (OR 2.44, 95% CI 1.03-5.79, P =0.044) but not fibrosis (P =0.618).MAFLD is associated with the risk of liver fibrosis and inflammatory activity in HBeAg-negative CHB patients. Sufficient attention should be paid to the prevention and treatment of MAFLD in patients with CHB, especially in HBeAg-negative patients." @default.
• W4225658840 created "2022-05-05" @default.
• W4225658840 creator A5024164106 @default.
• W4225658840 creator A5049626085 @default.
• W4225658840 creator A5050141240 @default.
• W4225658840 creator A5084187458 @default.
• W4225658840 creator A5084985894 @default.
• W4225658840 date "2022-03-01" @default.
• W4225658840 modified "2023-09-26" @default.
• W4225658840 title "MAFLD is Associated with the Risk of Liver Fibrosis and Inflammatory Activity in HBeAg-Negative CHB Patients" @default.
• W4225658840 cites W1963683487 @default.
• W4225658840 cites W1978656930 @default.
• W4225658840 cites W1984386483 @default.
• W4225658840 cites W2019596061 @default.
• W4225658840 cites W2035262207 @default.
• W4225658840 cites W2067740038 @default.
• W4225658840 cites W2104389844 @default.
• W4225658840 cites W2105079980 @default.
• W4225658840 cites W2120148668 @default.
• W4225658840 cites W2150649605 @default.
• W4225658840 cites W2155510029 @default.
• W4225658840 cites W2314866596 @default.
• W4225658840 cites W2342777953 @default.
• W4225658840 cites W2342974029 @default.
• W4225658840 cites W2531018086 @default.
• W4225658840 cites W2744645121 @default.
• W4225658840 cites W2844222709 @default.
• W4225658840 cites W2895545371 @default.
• W4225658840 cites W2898335685 @default.
• W4225658840 cites W2924326751 @default.
• W4225658840 cites W2957998339 @default.
• W4225658840 cites W2970114132 @default.
• W4225658840 cites W2991020873 @default.
• W4225658840 cites W3028440135 @default.
• W4225658840 cites W3032413621 @default.
• W4225658840 cites W3091471007 @default.
• W4225658840 cites W3109472849 @default.
• W4225658840 cites W3111217257 @default.
• W4225658840 cites W3122330053 @default.
• W4225658840 cites W3134080740 @default.
• W4225658840 cites W3167550451 @default.
• W4225658840 cites W3179078640 @default.
• W4225658840 cites W3183294941 @default.
• W4225658840 cites W3184822373 @default.
• W4225658840 cites W3187281785 @default.
• W4225658840 cites W3196825961 @default.
• W4225658840 cites W4200142755 @default.
• W4225658840 doi "https://doi.org/10.2147/dmso.s351492" @default.
• W4225658840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35256849" @default.
• W4225658840 hasPublicationYear "2022" @default.
• W4225658840 type Work @default.
• W4225658840 citedByCount "3" @default.
• W4225658840 countsByYear W42256588402022 @default.
• W4225658840 countsByYear W42256588402023 @default.
• W4225658840 crossrefType "journal-article" @default.
• W4225658840 hasAuthorship W4225658840A5024164106 @default.
• W4225658840 hasAuthorship W4225658840A5049626085 @default.
• W4225658840 hasAuthorship W4225658840A5050141240 @default.
• W4225658840 hasAuthorship W4225658840A5084187458 @default.
• W4225658840 hasAuthorship W4225658840A5084985894 @default.
• W4225658840 hasBestOaLocation W42256588401 @default.
• W4225658840 hasConcept C126322002 @default.
• W4225658840 hasConcept C151956035 @default.
• W4225658840 hasConcept C203014093 @default.
• W4225658840 hasConcept C2522874641 @default.
• W4225658840 hasConcept C2775934546 @default.
• W4225658840 hasConcept C2775940106 @default.
• W4225658840 hasConcept C2776029263 @default.
• W4225658840 hasConcept C2777410769 @default.
• W4225658840 hasConcept C2777766500 @default.
• W4225658840 hasConcept C2778772119 @default.
• W4225658840 hasConcept C2779134260 @default.
• W4225658840 hasConcept C2779384505 @default.
• W4225658840 hasConcept C2780559512 @default.
• W4225658840 hasConcept C2780593183 @default.
• W4225658840 hasConcept C71924100 @default.
• W4225658840 hasConcept C90924648 @default.
• W4225658840 hasConceptScore W4225658840C126322002 @default.
• W4225658840 hasConceptScore W4225658840C151956035 @default.
• W4225658840 hasConceptScore W4225658840C203014093 @default.
• W4225658840 hasConceptScore W4225658840C2522874641 @default.
• W4225658840 hasConceptScore W4225658840C2775934546 @default.
• W4225658840 hasConceptScore W4225658840C2775940106 @default.
• W4225658840 hasConceptScore W4225658840C2776029263 @default.
• W4225658840 hasConceptScore W4225658840C2777410769 @default.
• W4225658840 hasConceptScore W4225658840C2777766500 @default.
• W4225658840 hasConceptScore W4225658840C2778772119 @default.
• W4225658840 hasConceptScore W4225658840C2779134260 @default.
• W4225658840 hasConceptScore W4225658840C2779384505 @default.
• W4225658840 hasConceptScore W4225658840C2780559512 @default.
• W4225658840 hasConceptScore W4225658840C2780593183 @default.
• W4225658840 hasConceptScore W4225658840C71924100 @default.
• W4225658840 hasConceptScore W4225658840C90924648 @default.
• W4225658840 hasLocation W42256588401 @default.
• W4225658840 hasLocation W42256588402 @default.
• W4225658840 hasLocation W42256588403 @default.
• W4225658840 hasLocation W42256588404 @default.
• W4225658840 hasOpenAccess W4225658840 @default.

• next