FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225659918> ?p ?o ?g. }

• W4225659918 endingPage "9" @default.
• W4225659918 startingPage "1" @default.
• W4225659918 abstract "Some observational studies indicated the associations of relative carbohydrate, sugar, fat, and protein intake and Alzheimer's disease (AD). But it remains unclear whether the associations are causal.This study aimed to identify the effects of relative carbohydrate, sugar, fat, and protein intake in the diet on AD.A two-sample Mendelian randomization was employed. Finally, 14 independent lead SNPs remained in the Social Science Genetic Association Consortium. These SNPs of relative carbohydrate, sugar, fat, and protein intake at the level of genome-wide significance (p < 5×10-8) were used as instrumental variables. The summary data for AD were acquired from the International Genomics of Alzheimer's Project with a total of 54,162 individuals (17,008 AD patients and 37,154 control participants).This two-sample Mendelian randomization indicated that increased relative protein intake (per 1 standard deviation) causally decreased the AD risk (OR = 0.48, 95% CI: 0.24-0.95, p = 0.036), and increased relative fat intake may decrease the risk of AD (OR = 0.22, 95% CI: 0.06-0.86, p = 0.029). No statistical significance with AD risk was seen for relative carbohydrate or relative sugar intake.A higher relative intake of protein can causally reduce the risk of AD in the elderly. Additionally, a higher relative intake of fat may be protective against AD. No evidence showed that AD was associated with relative carbohydrate and sugar intake." @default.
• W4225659918 created "2022-05-05" @default.
• W4225659918 creator A5012272710 @default.
• W4225659918 creator A5012441626 @default.
• W4225659918 creator A5018254630 @default.
• W4225659918 creator A5020819058 @default.
• W4225659918 creator A5022778960 @default.
• W4225659918 creator A5022833514 @default.
• W4225659918 creator A5029240863 @default.
• W4225659918 creator A5042536439 @default.
• W4225659918 creator A5047054725 @default.
• W4225659918 creator A5052589766 @default.
• W4225659918 creator A5084378707 @default.
• W4225659918 date "2022-03-21" @default.
• W4225659918 modified "2023-10-16" @default.
• W4225659918 title "Causal Relationships Between Relative Intake from the Macronutrients and Alzheimer’s Disease: A Two-Sample Mendelian Randomization Study" @default.
• W4225659918 cites W1581753468 @default.
• W4225659918 cites W1902575419 @default.
• W4225659918 cites W1959125731 @default.
• W4225659918 cites W1963637177 @default.
• W4225659918 cites W1984042519 @default.
• W4225659918 cites W2009616695 @default.
• W4225659918 cites W2012953364 @default.
• W4225659918 cites W2023915132 @default.
• W4225659918 cites W2059023585 @default.
• W4225659918 cites W2107737108 @default.
• W4225659918 cites W2113699335 @default.
• W4225659918 cites W2115779804 @default.
• W4225659918 cites W2116101995 @default.
• W4225659918 cites W2116868464 @default.
• W4225659918 cites W2117200377 @default.
• W4225659918 cites W2146304004 @default.
• W4225659918 cites W2264206927 @default.
• W4225659918 cites W2304190440 @default.
• W4225659918 cites W2324862792 @default.
• W4225659918 cites W2329336071 @default.
• W4225659918 cites W2338785707 @default.
• W4225659918 cites W2398690791 @default.
• W4225659918 cites W2418725963 @default.
• W4225659918 cites W2490528887 @default.
• W4225659918 cites W2586864668 @default.
• W4225659918 cites W2593873915 @default.
• W4225659918 cites W2604218568 @default.
• W4225659918 cites W2772361019 @default.
• W4225659918 cites W2790509166 @default.
• W4225659918 cites W2802962038 @default.
• W4225659918 cites W2803072880 @default.
• W4225659918 cites W2805983714 @default.
• W4225659918 cites W2818417770 @default.
• W4225659918 cites W2907109585 @default.
• W4225659918 cites W2949390799 @default.
• W4225659918 cites W2975582353 @default.
• W4225659918 cites W3010779283 @default.
• W4225659918 cites W3023526808 @default.
• W4225659918 cites W3045787305 @default.
• W4225659918 cites W3048695309 @default.
• W4225659918 cites W3089262153 @default.
• W4225659918 cites W4210490568 @default.
• W4225659918 doi "https://doi.org/10.3233/jad-215535" @default.
• W4225659918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35342086" @default.
• W4225659918 hasPublicationYear "2022" @default.
• W4225659918 type Work @default.
• W4225659918 citedByCount "0" @default.
• W4225659918 crossrefType "journal-article" @default.
• W4225659918 hasAuthorship W4225659918A5012272710 @default.
• W4225659918 hasAuthorship W4225659918A5012441626 @default.
• W4225659918 hasAuthorship W4225659918A5018254630 @default.
• W4225659918 hasAuthorship W4225659918A5020819058 @default.
• W4225659918 hasAuthorship W4225659918A5022778960 @default.
• W4225659918 hasAuthorship W4225659918A5022833514 @default.
• W4225659918 hasAuthorship W4225659918A5029240863 @default.
• W4225659918 hasAuthorship W4225659918A5042536439 @default.
• W4225659918 hasAuthorship W4225659918A5047054725 @default.
• W4225659918 hasAuthorship W4225659918A5052589766 @default.
• W4225659918 hasAuthorship W4225659918A5084378707 @default.
• W4225659918 hasConcept C104317684 @default.
• W4225659918 hasConcept C126322002 @default.
• W4225659918 hasConcept C134018914 @default.
• W4225659918 hasConcept C135763542 @default.
• W4225659918 hasConcept C153209595 @default.
• W4225659918 hasConcept C2779134260 @default.
• W4225659918 hasConcept C2779901538 @default.
• W4225659918 hasConcept C2993967602 @default.
• W4225659918 hasConcept C42407357 @default.
• W4225659918 hasConcept C44249647 @default.
• W4225659918 hasConcept C502032728 @default.
• W4225659918 hasConcept C54355233 @default.
• W4225659918 hasConcept C71924100 @default.
• W4225659918 hasConcept C82789193 @default.
• W4225659918 hasConcept C86803240 @default.
• W4225659918 hasConceptScore W4225659918C104317684 @default.
• W4225659918 hasConceptScore W4225659918C126322002 @default.
• W4225659918 hasConceptScore W4225659918C134018914 @default.
• W4225659918 hasConceptScore W4225659918C135763542 @default.
• W4225659918 hasConceptScore W4225659918C153209595 @default.
• W4225659918 hasConceptScore W4225659918C2779134260 @default.
• W4225659918 hasConceptScore W4225659918C2779901538 @default.
• W4225659918 hasConceptScore W4225659918C2993967602 @default.

• next