Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225664280> ?p ?o ?g. }
- W4225664280 abstract "Abstract Catalytic strategies that provide stereoselective access to highly substituted alkenes from abundant monosubstituted substrates are exceedingly sought‐after but rare. Here, we show that a N ‐heterocyclic carbene‐Ni I catalytic species mediates efficient union of electronically polarized terminal olefins with benzyl chlorides, in the presence of trimethylsilyl triflate and trimethylamine additives, to generate trisubstituted boron‐ and arene‐containing trans alkenes in excellent regio‐ and stereoselectivities. Control experiments provide evidence for a mechanism involving branched‐selective Heck‐type benzylation that overrides substrate control, followed by trans ‐selective 1,3‐hydrogen shift. The method represents a significant addition to the toolbox of reactions for the concise synthesis of unsaturated biologically active compounds." @default.
- W4225664280 created "2022-05-05" @default.
- W4225664280 creator A5013822484 @default.
- W4225664280 creator A5061876765 @default.
- W4225664280 creator A5063138704 @default.
- W4225664280 creator A5073287889 @default.
- W4225664280 creator A5088614752 @default.
- W4225664280 date "2022-04-26" @default.
- W4225664280 modified "2023-10-16" @default.
- W4225664280 title "Stereoselective Synthesis of Trisubstituted Alkenes by Nickel‐Catalyzed Benzylation and Alkene Isomerization" @default.
- W4225664280 cites W1896970350 @default.
- W4225664280 cites W1968479888 @default.
- W4225664280 cites W1969913866 @default.
- W4225664280 cites W1979095716 @default.
- W4225664280 cites W1986649141 @default.
- W4225664280 cites W2004174458 @default.
- W4225664280 cites W2013121320 @default.
- W4225664280 cites W2033386652 @default.
- W4225664280 cites W2053418974 @default.
- W4225664280 cites W2074808135 @default.
- W4225664280 cites W2076602698 @default.
- W4225664280 cites W2133843639 @default.
- W4225664280 cites W2331405800 @default.
- W4225664280 cites W2528947799 @default.
- W4225664280 cites W2573197589 @default.
- W4225664280 cites W2592953986 @default.
- W4225664280 cites W2595036089 @default.
- W4225664280 cites W2610132190 @default.
- W4225664280 cites W2745044960 @default.
- W4225664280 cites W2766220264 @default.
- W4225664280 cites W2777661401 @default.
- W4225664280 cites W2782974785 @default.
- W4225664280 cites W2785620482 @default.
- W4225664280 cites W2803544643 @default.
- W4225664280 cites W2887099754 @default.
- W4225664280 cites W2897812858 @default.
- W4225664280 cites W2904250271 @default.
- W4225664280 cites W2911689993 @default.
- W4225664280 cites W2931574106 @default.
- W4225664280 cites W2969542994 @default.
- W4225664280 cites W2981617263 @default.
- W4225664280 cites W2999548403 @default.
- W4225664280 cites W3000701514 @default.
- W4225664280 cites W3001508512 @default.
- W4225664280 cites W3016817727 @default.
- W4225664280 cites W3024396725 @default.
- W4225664280 cites W3024436127 @default.
- W4225664280 cites W3133181546 @default.
- W4225664280 cites W3164828024 @default.
- W4225664280 cites W3190505920 @default.
- W4225664280 cites W3192201094 @default.
- W4225664280 cites W3194462314 @default.
- W4225664280 cites W3210401433 @default.
- W4225664280 cites W3212112252 @default.
- W4225664280 cites W4205984874 @default.
- W4225664280 doi "https://doi.org/10.1002/ange.202202674" @default.
- W4225664280 hasPublicationYear "2022" @default.
- W4225664280 type Work @default.
- W4225664280 citedByCount "0" @default.
- W4225664280 crossrefType "journal-article" @default.
- W4225664280 hasAuthorship W4225664280A5013822484 @default.
- W4225664280 hasAuthorship W4225664280A5061876765 @default.
- W4225664280 hasAuthorship W4225664280A5063138704 @default.
- W4225664280 hasAuthorship W4225664280A5073287889 @default.
- W4225664280 hasAuthorship W4225664280A5088614752 @default.
- W4225664280 hasConcept C126661725 @default.
- W4225664280 hasConcept C155647269 @default.
- W4225664280 hasConcept C161790260 @default.
- W4225664280 hasConcept C178790620 @default.
- W4225664280 hasConcept C181647583 @default.
- W4225664280 hasConcept C185592680 @default.
- W4225664280 hasConcept C21774173 @default.
- W4225664280 hasConcept C21951064 @default.
- W4225664280 hasConcept C2776254738 @default.
- W4225664280 hasConcept C2777164566 @default.
- W4225664280 hasConcept C59759590 @default.
- W4225664280 hasConceptScore W4225664280C126661725 @default.
- W4225664280 hasConceptScore W4225664280C155647269 @default.
- W4225664280 hasConceptScore W4225664280C161790260 @default.
- W4225664280 hasConceptScore W4225664280C178790620 @default.
- W4225664280 hasConceptScore W4225664280C181647583 @default.
- W4225664280 hasConceptScore W4225664280C185592680 @default.
- W4225664280 hasConceptScore W4225664280C21774173 @default.
- W4225664280 hasConceptScore W4225664280C21951064 @default.
- W4225664280 hasConceptScore W4225664280C2776254738 @default.
- W4225664280 hasConceptScore W4225664280C2777164566 @default.
- W4225664280 hasConceptScore W4225664280C59759590 @default.
- W4225664280 hasFunder F4320322725 @default.
- W4225664280 hasIssue "26" @default.
- W4225664280 hasLocation W42256642801 @default.
- W4225664280 hasOpenAccess W4225664280 @default.
- W4225664280 hasPrimaryLocation W42256642801 @default.
- W4225664280 hasRelatedWork W1595524749 @default.
- W4225664280 hasRelatedWork W2044299619 @default.
- W4225664280 hasRelatedWork W2061430027 @default.
- W4225664280 hasRelatedWork W2063116582 @default.
- W4225664280 hasRelatedWork W2332835267 @default.
- W4225664280 hasRelatedWork W2918122892 @default.
- W4225664280 hasRelatedWork W3135319404 @default.
- W4225664280 hasRelatedWork W4287815462 @default.