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- W4225706888 abstract "Hirschsprung's disease (HD) is a congenital disorder characterized by absence of intrinsic ganglion cells of the hindgut. It commonly presents in infancy with refractory constipation and failure to thrive. Short segment HD affecting the rectosigmoid region is the commonest variant. Although surgical or laparoscopic single or multi-stage pull-through procedures have been the gold standard for more than six decades, these procedures are associated with significant morbidity, recurrence, and often multi-stage procedures. Per-rectal endoscopic myotomy (PREM) is a recently described novel minimally invasive procedure based on the principles of third space endoscopy. It is based on the principle to open spastic aganglionic bowel segments by performing a myotomy through a submucosal tunnel. This review describes the patient selection and preparation and technique of PREM and discusses the status of PREM for treatment of HD." @default.
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- W4225706888 date "2023-05-01" @default.
- W4225706888 modified "2023-09-27" @default.
- W4225706888 title "Per rectal endoscopic myotomy for Hirschsprung's disease and megacolon" @default.
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- W4225706888 doi "https://doi.org/10.23736/s2724-5985.22.03166-7" @default.
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