FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225728313> ?p ?o ?g. }

• W4225728313 abstract "After emerging in China in late 2019, the novel Severe acute respiratory syndrome-like coronavirus 2 (SARS-CoV-2) spread worldwide and as of early 2021, continues to significantly impact most countries. Only a small number of coronaviruses are known to infect humans, and only two are associated with the severe outcomes associated with SARS-CoV-2: Severe acute respiratory syndrome-related coronavirus, a closely related species of SARS-CoV-2 that emerged in 2002, and Middle East respiratory syndrome-related coronavirus, which emerged in 2012. Both of these previous epidemics were controlled fairly rapidly through public health measures, and no vaccines or robust therapeutic interventions were identified. However, previous insights into the immune response to coronaviruses gained during the outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) have proved beneficial to identifying approaches to the treatment and prophylaxis of novel coronavirus disease 2019 (COVID-19). A number of potential therapeutics against SARS-CoV-2 and the resultant COVID-19 illness were rapidly identified, leading to a large number of clinical trials investigating a variety of possible therapeutic approaches being initiated early on in the pandemic. As a result, a small number of therapeutics have already been authorized by regulatory agencies such as the Food and Drug Administration (FDA) in the United States, and many other therapeutics remain under investigation. Here, we describe a range of approaches for the treatment of COVID-19, along with their proposed mechanisms of action and the current status of clinical investigation into each candidate. The status of these investigations will continue to evolve, and this review will be updated as progress is made." @default.
• W4225728313 created "2022-05-05" @default.
• W4225728313 creator A5001873566 @default.
• W4225728313 creator A5002953481 @default.
• W4225728313 creator A5019562492 @default.
• W4225728313 creator A5020020080 @default.
• W4225728313 creator A5021802451 @default.
• W4225728313 creator A5027753605 @default.
• W4225728313 creator A5034362700 @default.
• W4225728313 creator A5035868372 @default.
• W4225728313 creator A5036989840 @default.
• W4225728313 creator A5039755062 @default.
• W4225728313 creator A5042905167 @default.
• W4225728313 creator A5050692257 @default.
• W4225728313 creator A5053430115 @default.
• W4225728313 creator A5060662654 @default.
• W4225728313 creator A5062753139 @default.
• W4225728313 creator A5062823488 @default.
• W4225728313 creator A5065971122 @default.
• W4225728313 creator A5068519221 @default.
• W4225728313 creator A5072931739 @default.
• W4225728313 creator A5079331432 @default.
• W4225728313 creator A5083286341 @default.
• W4225728313 creator A5086882278 @default.
• W4225728313 creator A5087387706 @default.
• W4225728313 date "2021-12-21" @default.
• W4225728313 modified "2023-09-25" @default.
• W4225728313 title "Identification and Development of Therapeutics for COVID-19" @default.
• W4225728313 cites W1263158759 @default.
• W4225728313 cites W1513080541 @default.
• W4225728313 cites W1557707321 @default.
• W4225728313 cites W1584922384 @default.
• W4225728313 cites W1776476655 @default.
• W4225728313 cites W1961523492 @default.
• W4225728313 cites W1969791558 @default.
• W4225728313 cites W1971054351 @default.
• W4225728313 cites W1982210031 @default.
• W4225728313 cites W1985291129 @default.
• W4225728313 cites W1985390439 @default.
• W4225728313 cites W1986016424 @default.
• W4225728313 cites W1987912134 @default.
• W4225728313 cites W1991496259 @default.
• W4225728313 cites W1992043927 @default.
• W4225728313 cites W1995089537 @default.
• W4225728313 cites W1998383538 @default.
• W4225728313 cites W2003702772 @default.
• W4225728313 cites W2005302698 @default.
• W4225728313 cites W2007704080 @default.
• W4225728313 cites W2009123868 @default.
• W4225728313 cites W2012289331 @default.
• W4225728313 cites W2013539008 @default.
• W4225728313 cites W2013614403 @default.
• W4225728313 cites W2029677928 @default.
• W4225728313 cites W2030684251 @default.
• W4225728313 cites W2033645653 @default.
• W4225728313 cites W2036455421 @default.
• W4225728313 cites W2037849836 @default.
• W4225728313 cites W2038052574 @default.
• W4225728313 cites W2039941020 @default.
• W4225728313 cites W2040462356 @default.
• W4225728313 cites W2042504401 @default.
• W4225728313 cites W2047453275 @default.
• W4225728313 cites W2048093932 @default.
• W4225728313 cites W2050169388 @default.
• W4225728313 cites W2051103353 @default.
• W4225728313 cites W2052214665 @default.
• W4225728313 cites W2052712852 @default.
• W4225728313 cites W2054076340 @default.
• W4225728313 cites W2054210874 @default.
• W4225728313 cites W2054508896 @default.
• W4225728313 cites W2056277023 @default.
• W4225728313 cites W2058743202 @default.
• W4225728313 cites W2067833766 @default.
• W4225728313 cites W2068333272 @default.
• W4225728313 cites W2069836560 @default.
• W4225728313 cites W2071506940 @default.
• W4225728313 cites W2076250107 @default.
• W4225728313 cites W2081719521 @default.
• W4225728313 cites W2082708772 @default.
• W4225728313 cites W2082909688 @default.
• W4225728313 cites W2085433278 @default.
• W4225728313 cites W2087116399 @default.
• W4225728313 cites W2087251383 @default.
• W4225728313 cites W2095807050 @default.
• W4225728313 cites W2096098099 @default.
• W4225728313 cites W2099826587 @default.
• W4225728313 cites W2100478793 @default.
• W4225728313 cites W2100708757 @default.
• W4225728313 cites W2102978702 @default.
• W4225728313 cites W2103469603 @default.
• W4225728313 cites W2105314995 @default.
• W4225728313 cites W2105641709 @default.
• W4225728313 cites W2108367829 @default.
• W4225728313 cites W2110685381 @default.
• W4225728313 cites W2112130390 @default.
• W4225728313 cites W2119119130 @default.
• W4225728313 cites W2120088649 @default.
• W4225728313 cites W2123059506 @default.
• W4225728313 cites W2129239355 @default.
• W4225728313 cites W2132465034 @default.

• next