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- W4225751398 abstract "Abstract Purpose: To determine the effectiveness and safety of superior calyceal access compared with other calyceal access in percutaneous nephrolithotomy (PCNL). Methods: This meta-analysis was carried out according to preferred reporting items for systematic reviews and meta-analysis (PRISMA). We searched Pubmed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI) to identify relevant studies for this meta-analysis. Failed stone clearance event and complication event are two main outcomes, operation time and hospital stay time are two secondary outcomes. Relative data were extracted and assessed by using RevMan 5.3, Stata 15.0 and R 4.0.2. Results: 16 studies (8541 participants) were identified and included in this meta-analysis. Pooled results indicated that superior calyceal access could offer less failed stone clearance than other calyceal access (OR: 0.64, 95%CI: 0.47-0.88, P=0.006). No complication difference was found (OR: 1.10, 95%CI: 0.78-1.56, P=0.57). Superior calyceal access could offer shorter operation time (SMD: -0.57, 95%CI: -0.98, -0.15, P=0.007). No hospital stay difference was found (SMD: 0.07, 95%CI: -0.09, 0.22, P=0.38). Large heterogeneity was detected in stone clearance comparison (I 2 =71%, P<0.001) and operation time (I 2 =97%, P<0.001). Significant publication bias was also identified in stone clearance comparison (P=0.026). These defects weaken the credibility of results. Conclusion: Despite the considerable heterogeneity and publication bias, superior calyceal access in PCNL may bring better stone clearance rate, shorter operation time, with no increase in postoperative complication and hospital stay for patients with kidney stones. This finding still needs to be verified by larger randomized controlled trials." @default.
- W4225751398 created "2022-05-05" @default.
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- W4225751398 date "2022-04-04" @default.
- W4225751398 modified "2023-10-17" @default.
- W4225751398 title "Superior calyceal access versus other calyceal access in percutaneous nephrolithotomy: a systematic review and meta-analysis" @default.
- W4225751398 doi "https://doi.org/10.21203/rs.3.rs-1408102/v1" @default.
- W4225751398 hasPublicationYear "2022" @default.
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