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- W4225755267 abstract "Abstract Training of autobiographical memory has been proposed as intervention to improve cognitive functions. The neural substrates for such improvements are poorly understood. Several brain networks have been previously linked to autobiographical recollections, including the default mode network (DMN) and the sensorimotor network. Here we tested the hypothesis that different neural networks support distinct aspects of memory improvement in response to training on a group of 59 subjects. We found that memory training using olfactory cues increases resting-state intra-network DMN connectivity, and this associates with improved recollection of cue-specific memories. On the contrary, training decreased resting-state connectivity within the sensorimotor network, a decrease that correlated with improved ability for voluntary recall. Moreover, only the decrease in sensorimotor connectivity associated with the training-induced decrease in the TNFα factor, an immune modulation previously linked to improved cognitive performance. We identified functional and biochemical factors that associate with distinct memory processes improved by autobiographical training. Pathways which connect autobiographical memory to both high level cognition and somatic physiology are discussed." @default.
- W4225755267 created "2022-05-05" @default.
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- W4225755267 date "2021-12-02" @default.
- W4225755267 modified "2023-10-18" @default.
- W4225755267 title "Neural Networks Implicated in Autobiographical Memory Training" @default.
- W4225755267 doi "https://doi.org/10.21203/rs.3.rs-1121844/v1" @default.
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