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• W4225764398 abstract "Surgery is the cornerstone treatment for patients with primary or metastatic hepatic tumors. Thanks to surgical and anesthetic technological advances, current indications for liver resections have been significantly expanded to include any patient in whom all disease can be resected with a negative margin (R0) while preserving an adequate future residual liver (FRL). Posthepatectomy liver failure (PHLF) is still a feared complication following major liver surgery, associated with high morbidity, mortality and cost implications. PHLF is mainly linked to both the size and quality of the FRL. Significant advances have been made in detailed preoperative assessment to predict and mitigate this complication, even if an ideal methodology has yet to be defined. Several procedures have been described to induce hypertrophy of the FRL when needed. Each technique has its advantages and limitations, and among them portal vein embolization (PVE) is still considered the standard of care. About 20% of patients after PVE fail to undergo the scheduled hepatectomy, and newer secondary procedures, such as segment 4 embolization, ALPPS and HVE, have been proposed as salvage strategies. The aim of this review was to discuss the current modalities available and new perspectives in the optimization of FRL in patients undergoing major liver resection." @default.
• W4225764398 created "2022-05-05" @default.
• W4225764398 creator A5000750700 @default.
• W4225764398 creator A5009023321 @default.
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• W4225764398 creator A5031667913 @default.
• W4225764398 creator A5041843585 @default.
• W4225764398 creator A5060346886 @default.
• W4225764398 date "2022-07-01" @default.
• W4225764398 modified "2023-09-30" @default.
• W4225764398 title "Future remnant liver optimization: preoperative assessment, volume augmentation procedures and management of PVE failure" @default.
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• W4225764398 doi "https://doi.org/10.23736/s2724-5691.22.09541-7" @default.
• W4225764398 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35332767" @default.
• W4225764398 hasPublicationYear "2022" @default.

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