Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225805675> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W4225805675 endingPage "178" @default.
- W4225805675 startingPage "174" @default.
- W4225805675 abstract "The article presents data on the genome status of pregnant women in different trimesters of pregnancy, during the normal course of pregnancy. The variability of ribosomal cystone activation as well as the variability of genome stability (frequencies of chromosomal aberrations and fragile sites) in different trimesters of pregnancy have been studied to detect genome-specific functional variability for each trimester.It was found that the level of genome stability determined by the frequency of chromosomal structural disorders and fragile sites in all three trimesters of pregnancy did not differ significantly from similar rates for non-pregnant healthy women. The exception was the frequency of fragile sites in the first trimester of pregnancy, which was statistically significantly higher than the control rate, which may be a specific feature (characteristic) for this trimester of pregnancy.At the same time, specific variability in genomic parameters was identified. In particular, deheterochromatization of pericentromeric heterochromatin and heterochromatinization of the medial region and pretelomeric heterochromatin.Based on data on the activation of Nucleolar organizing regions of acrocentric chromosomes and changes in the frequency of acrocentric chromosome associations, which are statistically significantly higher than the control level, a conclusion is made about increased activity of protein-synthesizing apparatus of the cell in all three trimesters of pregnancy. A statistically significant increase in the associative activity of the 15 acrocentric chromosome in the third trimester of pregnancy has been identified, which may also indicate possible specific modification variability on this chromosome and be characteristic of a given trimester of pregnancy." @default.
- W4225805675 created "2022-05-05" @default.
- W4225805675 creator A5001816349 @default.
- W4225805675 creator A5011728634 @default.
- W4225805675 creator A5028549139 @default.
- W4225805675 creator A5048460905 @default.
- W4225805675 creator A5058860223 @default.
- W4225805675 creator A5076323468 @default.
- W4225805675 date "2021-12-01" @default.
- W4225805675 modified "2023-09-27" @default.
- W4225805675 title "[GENOMIC VARIABILITY DURING PREGNANCY TRIMESTERS]." @default.
- W4225805675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35000930" @default.
- W4225805675 hasPublicationYear "2021" @default.
- W4225805675 type Work @default.
- W4225805675 citedByCount "0" @default.
- W4225805675 crossrefType "journal-article" @default.
- W4225805675 hasAuthorship W4225805675A5001816349 @default.
- W4225805675 hasAuthorship W4225805675A5011728634 @default.
- W4225805675 hasAuthorship W4225805675A5028549139 @default.
- W4225805675 hasAuthorship W4225805675A5048460905 @default.
- W4225805675 hasAuthorship W4225805675A5058860223 @default.
- W4225805675 hasAuthorship W4225805675A5076323468 @default.
- W4225805675 hasConcept C103435993 @default.
- W4225805675 hasConcept C104317684 @default.
- W4225805675 hasConcept C131872663 @default.
- W4225805675 hasConcept C141231307 @default.
- W4225805675 hasConcept C2779234561 @default.
- W4225805675 hasConcept C3019714739 @default.
- W4225805675 hasConcept C30481170 @default.
- W4225805675 hasConcept C46973012 @default.
- W4225805675 hasConcept C54355233 @default.
- W4225805675 hasConcept C63491729 @default.
- W4225805675 hasConcept C71924100 @default.
- W4225805675 hasConcept C86803240 @default.
- W4225805675 hasConceptScore W4225805675C103435993 @default.
- W4225805675 hasConceptScore W4225805675C104317684 @default.
- W4225805675 hasConceptScore W4225805675C131872663 @default.
- W4225805675 hasConceptScore W4225805675C141231307 @default.
- W4225805675 hasConceptScore W4225805675C2779234561 @default.
- W4225805675 hasConceptScore W4225805675C3019714739 @default.
- W4225805675 hasConceptScore W4225805675C30481170 @default.
- W4225805675 hasConceptScore W4225805675C46973012 @default.
- W4225805675 hasConceptScore W4225805675C54355233 @default.
- W4225805675 hasConceptScore W4225805675C63491729 @default.
- W4225805675 hasConceptScore W4225805675C71924100 @default.
- W4225805675 hasConceptScore W4225805675C86803240 @default.
- W4225805675 hasIssue "321" @default.
- W4225805675 hasLocation W42258056751 @default.
- W4225805675 hasOpenAccess W4225805675 @default.
- W4225805675 hasPrimaryLocation W42258056751 @default.
- W4225805675 hasRelatedWork W1823395 @default.
- W4225805675 hasRelatedWork W19332571 @default.
- W4225805675 hasRelatedWork W26495077 @default.
- W4225805675 hasRelatedWork W27827979 @default.
- W4225805675 hasRelatedWork W29441346 @default.
- W4225805675 hasRelatedWork W33691713 @default.
- W4225805675 hasRelatedWork W36931611 @default.
- W4225805675 hasRelatedWork W40802774 @default.
- W4225805675 hasRelatedWork W46974271 @default.
- W4225805675 hasRelatedWork W47010048 @default.
- W4225805675 isParatext "false" @default.
- W4225805675 isRetracted "false" @default.
- W4225805675 workType "article" @default.