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- W4225806559 abstract "The aim: Was to study the state of the nitric oxide system, LPO and antioxidant system in the body of experimental animals in simulated metabolic syndrome. The aim of the study was to study the state of the nitric oxide system, lipid peroxidation and antioxidant system in the body of experimental animals in simulated MS.Materials and methods: The study was performed on 20 white male Wistar rats. Male control rats (n = 10) were fed a normal control diet. Male rats of the main group (n = 10) were fed a diet high in fat (over 60 % energy from fats) for 16 weeks, thus modeling the development of MS. The indicators of the prooxidant and antioxidant system, as well as the nitric oxide system were determined by photospectrographic method.Results: In animals with simulated MS, intensification of lipoperoxidation (statistically significantly higher level of TBA-active products 1.84 times), depletion of antioxidant protection (statistically significantly lower level of superoxide dismutase 2 times), activation of nitric oxide system (statistically significantly higher NO-synthase level 2.15 times) were found compared with intact animals.Conclusions: In animals with simulated MS, activation of lipid peroxidation processes, depletion of antioxidant protection and increased." @default.
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- W4225806559 date "2022-01-01" @default.
- W4225806559 modified "2023-09-30" @default.
- W4225806559 title "PATHOGENETIC ASPECTS OF METABOLIC SYNDROME IN EXPERIMENTAL ANIMALS" @default.
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- W4225806559 doi "https://doi.org/10.36740/wlek202202134" @default.
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