Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225826677> ?p ?o ?g. }
- W4225826677 endingPage "163" @default.
- W4225826677 startingPage "115" @default.
- W4225826677 abstract "The mitigation of plant toxins (detoxification) in the larvae of Lepidoptera (caterpillars) provides a rich milieu in which to understand the mechanisms driving the evolution and maintenance of ecological specialization. The field of coevolution was born through an intensive study of the interactions between secondary compounds of plants and Lepidoptera. Here, we summarize progress on our knowledge of the proximate (e.g., target site insensitivity to toxins) and ultimate (e.g., top-down vs. bottom-up) mechanisms used by caterpillars to cope with and even co-opt plant toxins. As new molecular tools become available, linking these two ends of the mechanistic spectrum (proximate and ultimate) is becoming possible. Our discussion of proximate mechanisms includes behavioral sensors of toxins (olfactory receptors, ionotropic receptors, gustatory receptors, transient receptor potential proteins, non-receptor chemosensory gene families), prevention of defense response induction, diversion strategies for precursor toxins, physical barriers, target site insensitivity, detoxification through xenobiotic metabolism, and microbial interactions. Ultimate mechanisms include those shaped by both bottom-up and top-down agents of natural selection in the context of detoxification, with clear links to other chapters of this volume (e.g., sequestration, parasitoids). Lessons learned about detoxification from arthropods other than Lepidoptera are covered as well, which can in turn be applied to caterpillars once appropriate tools become available." @default.
- W4225826677 created "2022-05-05" @default.
- W4225826677 creator A5023532647 @default.
- W4225826677 creator A5069728842 @default.
- W4225826677 date "2022-01-01" @default.
- W4225826677 modified "2023-09-25" @default.
- W4225826677 title "Ecology and Evolution of Secondary Compound Detoxification Systems in Caterpillars" @default.
- W4225826677 cites W1032848452 @default.
- W4225826677 cites W1486329624 @default.
- W4225826677 cites W149640850 @default.
- W4225826677 cites W1509560578 @default.
- W4225826677 cites W1548569689 @default.
- W4225826677 cites W1557506896 @default.
- W4225826677 cites W1603281523 @default.
- W4225826677 cites W1760540767 @default.
- W4225826677 cites W1816432249 @default.
- W4225826677 cites W1875727809 @default.
- W4225826677 cites W1917204293 @default.
- W4225826677 cites W1941481034 @default.
- W4225826677 cites W1964061190 @default.
- W4225826677 cites W1965306932 @default.
- W4225826677 cites W1965917470 @default.
- W4225826677 cites W1966574857 @default.
- W4225826677 cites W1968606309 @default.
- W4225826677 cites W1968747033 @default.
- W4225826677 cites W1971000607 @default.
- W4225826677 cites W1971145042 @default.
- W4225826677 cites W1971188096 @default.
- W4225826677 cites W1972236803 @default.
- W4225826677 cites W1972815843 @default.
- W4225826677 cites W1973508181 @default.
- W4225826677 cites W1977673585 @default.
- W4225826677 cites W1977822537 @default.
- W4225826677 cites W1979357782 @default.
- W4225826677 cites W1982486848 @default.
- W4225826677 cites W1983617242 @default.
- W4225826677 cites W1983859416 @default.
- W4225826677 cites W1984174572 @default.
- W4225826677 cites W1988398931 @default.
- W4225826677 cites W1989772807 @default.
- W4225826677 cites W1990645569 @default.
- W4225826677 cites W1991189631 @default.
- W4225826677 cites W1991678230 @default.
- W4225826677 cites W1992135293 @default.
- W4225826677 cites W1992453008 @default.
- W4225826677 cites W1992894824 @default.
- W4225826677 cites W1994763519 @default.
- W4225826677 cites W1995828353 @default.
- W4225826677 cites W1996548324 @default.
- W4225826677 cites W1998356880 @default.
- W4225826677 cites W1999739739 @default.
- W4225826677 cites W2000328160 @default.
- W4225826677 cites W2001833477 @default.
- W4225826677 cites W2004205578 @default.
- W4225826677 cites W2004428759 @default.
- W4225826677 cites W2004535684 @default.
- W4225826677 cites W2005074759 @default.
- W4225826677 cites W2005516932 @default.
- W4225826677 cites W2005536513 @default.
- W4225826677 cites W2005906963 @default.
- W4225826677 cites W2008133122 @default.
- W4225826677 cites W2008239001 @default.
- W4225826677 cites W2014408769 @default.
- W4225826677 cites W2014424798 @default.
- W4225826677 cites W2015621327 @default.
- W4225826677 cites W2016666153 @default.
- W4225826677 cites W2017980106 @default.
- W4225826677 cites W2018077219 @default.
- W4225826677 cites W2019647674 @default.
- W4225826677 cites W2020677946 @default.
- W4225826677 cites W2021579219 @default.
- W4225826677 cites W2022124968 @default.
- W4225826677 cites W2022751627 @default.
- W4225826677 cites W2022877091 @default.
- W4225826677 cites W2023182268 @default.
- W4225826677 cites W2023195590 @default.
- W4225826677 cites W2023572295 @default.
- W4225826677 cites W2025276462 @default.
- W4225826677 cites W2027532052 @default.
- W4225826677 cites W2027598184 @default.
- W4225826677 cites W2029159321 @default.
- W4225826677 cites W2029436323 @default.
- W4225826677 cites W2029925882 @default.
- W4225826677 cites W2031107821 @default.
- W4225826677 cites W2031923105 @default.
- W4225826677 cites W2032033999 @default.
- W4225826677 cites W2032319419 @default.
- W4225826677 cites W2033527615 @default.
- W4225826677 cites W2034637982 @default.
- W4225826677 cites W2036681657 @default.
- W4225826677 cites W2036762868 @default.
- W4225826677 cites W2037963925 @default.
- W4225826677 cites W2039398693 @default.
- W4225826677 cites W2042620313 @default.
- W4225826677 cites W2043176585 @default.
- W4225826677 cites W2043261622 @default.
- W4225826677 cites W2043331140 @default.
- W4225826677 cites W2048060610 @default.