FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225831656> ?p ?o ?g. }

• W4225831656 abstract "Gliomas are often diagnosed due to epileptic seizures as well as neurocognitive deficits. First treatment choice for patients with gliomas in speech-related areas is awake surgery, which aims at maximizing tumor resection while preserving or improving patient's neurological status. The present study aimed at evaluating neurocognitive functioning and occurrence of epileptic seizures in patients suffering from gliomas located in language-related areas before and after awake surgery as well as during their follow up course of disease.In this prospective study we included patients who underwent awake surgery for glioma in the inferior frontal gyrus, superior temporal gyrus, or anterior temporal lobe. Preoperatively, as well as in the short-term (median 4.1 months, IQR 2.1-6.0) and long-term (median 18.3 months, IQR 12.3-36.6) postoperative course, neurocognitive functioning, neurologic status, the occurrence of epileptic seizures and number of antiepileptic drugs were recorded.Between 09/2012 and 09/2019, a total of 27 glioma patients, aged 36.1 ± 11.8 years, were included. Tumor resection was complete in 15, subtotal in 6 and partial in 6 patients, respectively. While preoperatively impairment in at least one neurocognitive domain was found in 37.0% of patients, postoperatively, in the short-term, 36.4% of patients presented a significant deterioration in word fluency (p=0.009) and 34.8% of patients in executive functions (p=0.049). Over the long-term, scores improved to preoperative baseline levels. The number of patients with mood disturbances significantly declined from 66.7% to 34.8% after surgery (p=0.03). Regarding seizures, these were present in 18 (66.7%) patients prior to surgery. Postoperatively, 22 (81.5%) patients were treated with antiepileptic drugs with all patients presenting seizure-freedom.In patients suffering from gliomas in eloquent areas, the combination of awake surgery, regular neurocognitive assessment - considering individual patients´ functional outcome and rehabilitation needs - and the individual adjustment of antiepileptic therapy results in excellent patient outcome in the long-term course." @default.
• W4225831656 created "2022-05-05" @default.
• W4225831656 creator A5034513075 @default.
• W4225831656 creator A5035770881 @default.
• W4225831656 creator A5043606338 @default.
• W4225831656 creator A5049926907 @default.
• W4225831656 creator A5054857250 @default.
• W4225831656 creator A5066119011 @default.
• W4225831656 creator A5069623440 @default.
• W4225831656 creator A5071106990 @default.
• W4225831656 creator A5080788469 @default.
• W4225831656 creator A5089058261 @default.
• W4225831656 date "2022-04-07" @default.
• W4225831656 modified "2023-09-30" @default.
• W4225831656 title "Neurocognitive Outcome and Seizure Freedom After Awake Surgery of Gliomas" @default.
• W4225831656 cites W1535687732 @default.
• W4225831656 cites W1972227425 @default.
• W4225831656 cites W1989474634 @default.
• W4225831656 cites W1996183804 @default.
• W4225831656 cites W2003097798 @default.
• W4225831656 cites W2015313936 @default.
• W4225831656 cites W2029160811 @default.
• W4225831656 cites W2032267642 @default.
• W4225831656 cites W2038806872 @default.
• W4225831656 cites W2043166146 @default.
• W4225831656 cites W2072498274 @default.
• W4225831656 cites W2082380006 @default.
• W4225831656 cites W2105420171 @default.
• W4225831656 cites W2110102835 @default.
• W4225831656 cites W2111042597 @default.
• W4225831656 cites W2113460821 @default.
• W4225831656 cites W2122926939 @default.
• W4225831656 cites W2134547003 @default.
• W4225831656 cites W2136022845 @default.
• W4225831656 cites W2142254723 @default.
• W4225831656 cites W2143879783 @default.
• W4225831656 cites W2148977460 @default.
• W4225831656 cites W2162643152 @default.
• W4225831656 cites W2257511402 @default.
• W4225831656 cites W2315194684 @default.
• W4225831656 cites W2366536035 @default.
• W4225831656 cites W2766381907 @default.
• W4225831656 cites W2900559205 @default.
• W4225831656 cites W2939093001 @default.
• W4225831656 cites W2940553614 @default.
• W4225831656 cites W2992004705 @default.
• W4225831656 cites W3001166901 @default.
• W4225831656 cites W3016081766 @default.
• W4225831656 cites W3020099303 @default.
• W4225831656 cites W3030239682 @default.
• W4225831656 cites W3087610266 @default.
• W4225831656 cites W3092153838 @default.
• W4225831656 cites W3107520175 @default.
• W4225831656 cites W3136689170 @default.
• W4225831656 cites W4211220688 @default.
• W4225831656 cites W4241771140 @default.
• W4225831656 cites W4245932665 @default.
• W4225831656 cites W4291982393 @default.
• W4225831656 doi "https://doi.org/10.3389/fonc.2022.815733" @default.
• W4225831656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35463387" @default.
• W4225831656 hasPublicationYear "2022" @default.
• W4225831656 type Work @default.
• W4225831656 citedByCount "1" @default.
• W4225831656 countsByYear W42258316562022 @default.
• W4225831656 crossrefType "journal-article" @default.
• W4225831656 hasAuthorship W4225831656A5034513075 @default.
• W4225831656 hasAuthorship W4225831656A5035770881 @default.
• W4225831656 hasAuthorship W4225831656A5043606338 @default.
• W4225831656 hasAuthorship W4225831656A5049926907 @default.
• W4225831656 hasAuthorship W4225831656A5054857250 @default.
• W4225831656 hasAuthorship W4225831656A5066119011 @default.
• W4225831656 hasAuthorship W4225831656A5069623440 @default.
• W4225831656 hasAuthorship W4225831656A5071106990 @default.
• W4225831656 hasAuthorship W4225831656A5080788469 @default.
• W4225831656 hasAuthorship W4225831656A5089058261 @default.
• W4225831656 hasBestOaLocation W42258316561 @default.
• W4225831656 hasConcept C118552586 @default.
• W4225831656 hasConcept C141071460 @default.
• W4225831656 hasConcept C14216870 @default.
• W4225831656 hasConcept C169900460 @default.
• W4225831656 hasConcept C172467417 @default.
• W4225831656 hasConcept C2778186239 @default.
• W4225831656 hasConcept C2778227246 @default.
• W4225831656 hasConcept C2780733359 @default.
• W4225831656 hasConcept C2781099131 @default.
• W4225831656 hasConcept C42219234 @default.
• W4225831656 hasConcept C502942594 @default.
• W4225831656 hasConcept C71924100 @default.
• W4225831656 hasConcept C97530452 @default.
• W4225831656 hasConceptScore W4225831656C118552586 @default.
• W4225831656 hasConceptScore W4225831656C141071460 @default.
• W4225831656 hasConceptScore W4225831656C14216870 @default.
• W4225831656 hasConceptScore W4225831656C169900460 @default.
• W4225831656 hasConceptScore W4225831656C172467417 @default.
• W4225831656 hasConceptScore W4225831656C2778186239 @default.
• W4225831656 hasConceptScore W4225831656C2778227246 @default.
• W4225831656 hasConceptScore W4225831656C2780733359 @default.
• W4225831656 hasConceptScore W4225831656C2781099131 @default.
• W4225831656 hasConceptScore W4225831656C42219234 @default.
• W4225831656 hasConceptScore W4225831656C502942594 @default.

• next