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• W4225883658 abstract "Abstract Background DNA methylation is thought to influence the expression of genes, especially in response to changing environmental conditions and developmental changes. Sugar beet ( Beta vulgaris ssp. vulgaris ), and other biennial or perennial plants are inevitably exposed to fluctuating temperatures throughout their lifecycle and might even require such stimulus to acquire floral competence. Therefore, plants such as beets, need to fine-tune their epigenetic makeup to ensure phenotypic plasticity towards changing environmental conditions while at the same time steering essential developmental processes. Different crop species may show opposing reactions towards the same abiotic stress, or, vice versa, identical species may respond differently depending on the specific kind of stress. Results In this study, we investigated common effects of cold treatment on genome-wide DNA methylation and gene expression of two Beta vulgaris accessions via multi-omics data analysis. Cold exposure resulted in a pronounced reduction of DNA methylation levels, which particularly affected methylation in CHH context (and to a lesser extent CHG) and was accompanied by transcriptional downregulation of the chromomethyltransferase CMT2 and strong upregulation of several genes mediating active DNA demethylation. Conclusion Integration of methylomic and transcriptomic data revealed that, rather than methylation having directly influenced expression, epigenetic modifications correlated with changes in expression of known players involved in DNA (de)methylation. In particular, cold triggered upregulation of genes putatively contributing to DNA demethylation via the ROS1 pathway. Our observations suggest that these transcriptional responses precede the cold-induced global DNA-hypomethylation in non-CpG, preparing beets for additional transcriptional alterations necessary for adapting to upcoming environmental changes." @default.
• W4225883658 created "2022-05-05" @default.
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• W4225883658 date "2022-02-17" @default.
• W4225883658 modified "2023-10-18" @default.
• W4225883658 title "Multi-omics data integration reveals link between epigenetic modifications and gene expression in sugar beet (Beta vulgaris subsp. vulgaris) in response to cold" @default.
• W4225883658 cites W1560609485 @default.
• W4225883658 cites W1643740851 @default.
• W4225883658 cites W1663994257 @default.
• W4225883658 cites W1681030413 @default.
• W4225883658 cites W1941111614 @default.
• W4225883658 cites W1960142378 @default.
• W4225883658 cites W1968466047 @default.
• W4225883658 cites W1973094248 @default.
• W4225883658 cites W1974988542 @default.
• W4225883658 cites W1984251741 @default.
• W4225883658 cites W1984891757 @default.
• W4225883658 cites W1989568035 @default.
• W4225883658 cites W1996281854 @default.
• W4225883658 cites W1998229632 @default.
• W4225883658 cites W1998901058 @default.
• W4225883658 cites W2002815900 @default.
• W4225883658 cites W2004798786 @default.
• W4225883658 cites W2008029788 @default.
• W4225883658 cites W2013033579 @default.
• W4225883658 cites W2016813268 @default.
• W4225883658 cites W2019471731 @default.
• W4225883658 cites W2019739870 @default.
• W4225883658 cites W2020173141 @default.
• W4225883658 cites W2021735982 @default.
• W4225883658 cites W2024848067 @default.
• W4225883658 cites W2025564004 @default.
• W4225883658 cites W2026343134 @default.
• W4225883658 cites W2029687716 @default.
• W4225883658 cites W2031297525 @default.
• W4225883658 cites W2037797217 @default.
• W4225883658 cites W2048846949 @default.
• W4225883658 cites W2050621445 @default.
• W4225883658 cites W2057162139 @default.
• W4225883658 cites W2059979506 @default.
• W4225883658 cites W2060586846 @default.
• W4225883658 cites W2064489231 @default.
• W4225883658 cites W2065064903 @default.
• W4225883658 cites W2067151470 @default.
• W4225883658 cites W2068634134 @default.
• W4225883658 cites W2079911234 @default.
• W4225883658 cites W2080923073 @default.
• W4225883658 cites W2082156565 @default.
• W4225883658 cites W2085338556 @default.
• W4225883658 cites W2090042982 @default.
• W4225883658 cites W2091722627 @default.
• W4225883658 cites W2097321620 @default.
• W4225883658 cites W2097605374 @default.
• W4225883658 cites W2099908820 @default.
• W4225883658 cites W2100686198 @default.
• W4225883658 cites W2103255565 @default.
• W4225883658 cites W2103444581 @default.
• W4225883658 cites W2105286253 @default.
• W4225883658 cites W2108031268 @default.
• W4225883658 cites W2109806977 @default.
• W4225883658 cites W2113776804 @default.
• W4225883658 cites W2117309809 @default.
• W4225883658 cites W2123921804 @default.
• W4225883658 cites W2124866820 @default.
• W4225883658 cites W2125484064 @default.
• W4225883658 cites W2127524244 @default.
• W4225883658 cites W2131374955 @default.
• W4225883658 cites W2133170643 @default.
• W4225883658 cites W2138207763 @default.
• W4225883658 cites W2139368808 @default.
• W4225883658 cites W2150194502 @default.
• W4225883658 cites W2150518045 @default.
• W4225883658 cites W2151476452 @default.
• W4225883658 cites W2155772493 @default.
• W4225883658 cites W2161227229 @default.
• W4225883658 cites W2162648640 @default.
• W4225883658 cites W2163003877 @default.
• W4225883658 cites W2165290732 @default.
• W4225883658 cites W2165941008 @default.
• W4225883658 cites W2167183449 @default.
• W4225883658 cites W2169456326 @default.
• W4225883658 cites W2170099595 @default.
• W4225883658 cites W2170828323 @default.
• W4225883658 cites W2179438025 @default.
• W4225883658 cites W2245259384 @default.
• W4225883658 cites W2432815617 @default.

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