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• W4225905907 endingPage "717" @default.
• W4225905907 startingPage "703" @default.
• W4225905907 abstract "Fracture non-union is a significant orthopaedic problem affecting a substantial number of patients yearly. Treatment of nonunions is devastating to patients and costly to the healthcare system. Unfortunately, the diagnosis of non-union is typically made in a reactionary fashion by an orthopaedic surgeon based on clinical assessment and radiographic features several months into treatment. For this reason, investigators have been trying to develop prediction algorithms; however, these have relied on population-based approaches and lack the predictive capability necessary to make individual treatment decisions. There is also a growing body of literature focussed on identifying blood biomarkers that are associated with non-union. This review describes the research that has been done in this area. Further studies of patient-centered, precision medicine approaches will likely improve fracture non-union diagnostic/prognostic capabilities." @default.
• W4225905907 created "2022-05-05" @default.
• W4225905907 creator A5022981772 @default.
• W4225905907 creator A5034416233 @default.
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• W4225905907 creator A5052244336 @default.
• W4225905907 creator A5063263944 @default.
• W4225905907 creator A5074659892 @default.
• W4225905907 creator A5082731692 @default.
• W4225905907 date "2021-10-03" @default.
• W4225905907 modified "2023-09-26" @default.
• W4225905907 title "Predicting fracture healing with blood biomarkers: the potential to assess patient risk of fracture nonunion" @default.
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