FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4225984145> ?p ?o ?g. }

• W4225984145 endingPage "e0265048" @default.
• W4225984145 startingPage "e0265048" @default.
• W4225984145 abstract "Cutaneous melanoma rates are steadily increasing. Up to 20% of patients diagnosed with AJCC Stage I/II melanomas will develop metastatic disease. To date there are no consistently reliable means to accurately identify truly high versus low-risk patient subpopulations. There is hence an urgent need for more accurate prediction of prognosis to determine appropriate clinical management. Validation of a novel prognostic test based on the immunohistochemical expression of two protein biomarkers in the epidermal microenvironment of primary melanomas was undertaken; loss of these biomarkers had previously been shown to be associated with a higher risk of recurrence or metastasis. A parallel qualitative study exploring secondary care health professional and patient views of the test was undertaken and this paper reports the perceived barriers and enablers to its implementation into the melanoma care pathway.Qualitative methods were employed drawing upon the Theoretical Domains Framework (TDF) in the exploration and analysis. An inductive-deductive analysis was performed, with all data coded using a thematic then TDF framework.20 dermatologists, plastic surgeons, cancer nurse specialists, oncologists and histopathologists participated. Nine TDF domains were relevant to all health professional groups and the 'Skills' and 'Beliefs about Capabilities' domains were relevant only to histopathologists. 'Optimism' and 'Beliefs about consequences' were strong enablers particularly for clinicians. 'Environmental context and resources' (impact on pathology services) and 'Knowledge' (the need for robust evidence about the test reliability) were the main perceived barriers. 19 patients and one carer were interviewed. For the patients eight domains were relevant. ('Knowledge', 'Emotions', 'Beliefs about consequences', 'Social Role and identity', 'Behavioural regulation', 'Memory, attention and decision processes', 'Reinforcement' and 'Skills'). The consequences of the implementation of the test were reassurance about future risk, changes to the follow-up pathway on which there were mixed views, and the need to ensure they maintained self-surveillance (Beliefs about consequences). The test was acceptable to all patient interviewees but the resultant changes to management would need to be supported by mechanisms for fast-track back into the clinic, further information on self-surveillance and clear management plans at the time the result is conveyed (Behavioural regulation).Health professionals and patients perceived positive consequences-for patients and for health services-of adopting the test. However, its implementation would require exploration of the resource implications for pathology services, psychological support for patients with a high-risk test result and mechanisms to reassure and support patients should the test lead to reduced frequency or duration of follow-up. Exploring implementation at an early stage with health professionals presented challenges related to the provision of specific details of the test and its validation." @default.
• W4225984145 created "2022-05-05" @default.
• W4225984145 creator A5008793366 @default.
• W4225984145 creator A5014325821 @default.
• W4225984145 creator A5020335882 @default.
• W4225984145 creator A5044754179 @default.
• W4225984145 creator A5057300951 @default.
• W4225984145 date "2022-04-04" @default.
• W4225984145 modified "2023-10-18" @default.
• W4225984145 title "Health professional and patient views of a novel prognostic test for melanoma: A theoretically informed qualitative study" @default.
• W4225984145 cites W1500801700 @default.
• W4225984145 cites W1979290264 @default.
• W4225984145 cites W2023677003 @default.
• W4225984145 cites W2057714133 @default.
• W4225984145 cites W2077109464 @default.
• W4225984145 cites W2108181863 @default.
• W4225984145 cites W2116567300 @default.
• W4225984145 cites W2142149055 @default.
• W4225984145 cites W2167835377 @default.
• W4225984145 cites W2591428325 @default.
• W4225984145 cites W2613860426 @default.
• W4225984145 cites W2674995983 @default.
• W4225984145 cites W2762347490 @default.
• W4225984145 cites W2789503488 @default.
• W4225984145 cites W2943114032 @default.
• W4225984145 cites W2964699959 @default.
• W4225984145 cites W3034069549 @default.
• W4225984145 cites W3036757896 @default.
• W4225984145 cites W3156918560 @default.
• W4225984145 doi "https://doi.org/10.1371/journal.pone.0265048" @default.
• W4225984145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35377887" @default.
• W4225984145 hasPublicationYear "2022" @default.
• W4225984145 type Work @default.
• W4225984145 citedByCount "1" @default.
• W4225984145 countsByYear W42259841452023 @default.
• W4225984145 crossrefType "journal-article" @default.
• W4225984145 hasAuthorship W4225984145A5008793366 @default.
• W4225984145 hasAuthorship W4225984145A5014325821 @default.
• W4225984145 hasAuthorship W4225984145A5020335882 @default.
• W4225984145 hasAuthorship W4225984145A5044754179 @default.
• W4225984145 hasAuthorship W4225984145A5057300951 @default.
• W4225984145 hasBestOaLocation W42259841451 @default.
• W4225984145 hasConcept C142724271 @default.
• W4225984145 hasConcept C144024400 @default.
• W4225984145 hasConcept C151730666 @default.
• W4225984145 hasConcept C15744967 @default.
• W4225984145 hasConcept C160735492 @default.
• W4225984145 hasConcept C162324750 @default.
• W4225984145 hasConcept C190248442 @default.
• W4225984145 hasConcept C2777267654 @default.
• W4225984145 hasConcept C2779134260 @default.
• W4225984145 hasConcept C2779343474 @default.
• W4225984145 hasConcept C36289849 @default.
• W4225984145 hasConcept C50522688 @default.
• W4225984145 hasConcept C512399662 @default.
• W4225984145 hasConcept C71924100 @default.
• W4225984145 hasConcept C74196892 @default.
• W4225984145 hasConcept C86803240 @default.
• W4225984145 hasConceptScore W4225984145C142724271 @default.
• W4225984145 hasConceptScore W4225984145C144024400 @default.
• W4225984145 hasConceptScore W4225984145C151730666 @default.
• W4225984145 hasConceptScore W4225984145C15744967 @default.
• W4225984145 hasConceptScore W4225984145C160735492 @default.
• W4225984145 hasConceptScore W4225984145C162324750 @default.
• W4225984145 hasConceptScore W4225984145C190248442 @default.
• W4225984145 hasConceptScore W4225984145C2777267654 @default.
• W4225984145 hasConceptScore W4225984145C2779134260 @default.
• W4225984145 hasConceptScore W4225984145C2779343474 @default.
• W4225984145 hasConceptScore W4225984145C36289849 @default.
• W4225984145 hasConceptScore W4225984145C50522688 @default.
• W4225984145 hasConceptScore W4225984145C512399662 @default.
• W4225984145 hasConceptScore W4225984145C71924100 @default.
• W4225984145 hasConceptScore W4225984145C74196892 @default.
• W4225984145 hasConceptScore W4225984145C86803240 @default.
• W4225984145 hasFunder F4320335360 @default.
• W4225984145 hasIssue "4" @default.
• W4225984145 hasLocation W42259841451 @default.
• W4225984145 hasLocation W42259841452 @default.
• W4225984145 hasLocation W42259841453 @default.
• W4225984145 hasLocation W42259841454 @default.
• W4225984145 hasOpenAccess W4225984145 @default.
• W4225984145 hasPrimaryLocation W42259841451 @default.
• W4225984145 hasRelatedWork W1842739385 @default.
• W4225984145 hasRelatedWork W2004690316 @default.
• W4225984145 hasRelatedWork W2024825203 @default.
• W4225984145 hasRelatedWork W2132185073 @default.
• W4225984145 hasRelatedWork W2333440397 @default.
• W4225984145 hasRelatedWork W2748952813 @default.
• W4225984145 hasRelatedWork W2796180820 @default.
• W4225984145 hasRelatedWork W2899084033 @default.
• W4225984145 hasRelatedWork W2903552034 @default.
• W4225984145 hasRelatedWork W647494715 @default.
• W4225984145 hasVolume "17" @default.
• W4225984145 isParatext "false" @default.
• W4225984145 isRetracted "false" @default.
• W4225984145 workType "article" @default.