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• W4226022433 abstract "Abstract Conduction velocity is the speed at which electrical signals travel along axons and is a crucial determinant of neural communication. Inferences about conduction velocity can now be made in vivo in humans using a measure called the magnetic resonance (MR) g-ratio. This is the ratio of the inner axon diameter relative to that of the axon plus the myelin sheath that encases it. Here, in the first application to cognition, we found that variations in MR g-ratio, and by inference conduction velocity, of the parahippocampal cingulum bundle were associated with autobiographical memory recall ability in 217 healthy adults. This tract connects the hippocampus with a range of other brain areas. We further observed that the association seemed to be with inner axon diameter rather than myelin content. The extent to which neurites were coherently organised within the parahippocampal cingulum bundle was also linked with autobiographical memory recall ability. Moreover, these findings were specific to autobiographical memory recall, and were not apparent for laboratory-based memory tests. Our results offer a new perspective on individual differences in autobiographical memory recall ability, highlighting the possible influence of specific features of white matter microstructure when recalling detailed memories of our real-life past experiences." @default.
• W4226022433 created "2022-05-05" @default.
• W4226022433 creator A5023367721 @default.
• W4226022433 creator A5039371416 @default.
• W4226022433 creator A5062724086 @default.
• W4226022433 creator A5086856273 @default.
• W4226022433 date "2022-04-07" @default.
• W4226022433 modified "2023-09-28" @default.
• W4226022433 title "Conduction velocity along a key white matter tract is associated with autobiographical memory recall ability" @default.
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