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- W4226061570 abstract "It is widely recognized that microbial disorders are involved in the pathogenesis of many malignant tumors. The oral and intestinal tract are two of the overriding microbial habitats in the human body. Although they are anatomically and physiologically continuous, belonging to the openings at both ends of the digestive tract, the oral and intestinal microbiome do not cross talk with each other due to a variety of reasons, including intestinal microbial colonization resistance and chemical barriers in the upper digestive tract. However, this balance can be upset in certain circumstances, such as disruption of colonization resistance of gut microbes, intestinal inflammation, and disruption of the digestive tract chemical barrier. Evidence is now accruing to suggest that the oral microbiome can colonize the gut, leading to dysregulation of the gut microbes. Furthermore, the oral-gut microbes create an intestinal inflammatory and immunosuppressive microenvironment conducive to tumorigenesis and progression of colorectal cancer (CRC). Here, we review the oral to intestinal microbial transmission and the inflammatory and immunosuppressive microenvironment, induced by oral-gut axis microbes in the gut. A superior comprehension of the contribution of the oral-intestinal microbes to CRC provides new insights into the prevention and treatment of CRC in the future." @default.
- W4226061570 created "2022-05-05" @default.
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- W4226061570 creator A5053234159 @default.
- W4226061570 creator A5071986915 @default.
- W4226061570 date "2022-02-01" @default.
- W4226061570 modified "2023-10-16" @default.
- W4226061570 title "Oral-Intestinal Microbiota in Colorectal Cancer: Inflammation and Immunosuppression" @default.
- W4226061570 cites W1601071501 @default.
- W4226061570 cites W1912311803 @default.
- W4226061570 cites W1990515033 @default.
- W4226061570 cites W1994311022 @default.
- W4226061570 cites W2015336843 @default.
- W4226061570 cites W2024372253 @default.
- W4226061570 cites W2029399624 @default.
- W4226061570 cites W2032230795 @default.
- W4226061570 cites W2045218929 @default.
- W4226061570 cites W2060610804 @default.
- W4226061570 cites W2072944905 @default.
- W4226061570 cites W2081653606 @default.
- W4226061570 cites W2096139589 @default.
- W4226061570 cites W2097925313 @default.
- W4226061570 cites W2101565190 @default.
- W4226061570 cites W2117618256 @default.
- W4226061570 cites W2128769815 @default.
- W4226061570 cites W2130725058 @default.
- W4226061570 cites W2134647062 @default.
- W4226061570 cites W2135846774 @default.
- W4226061570 cites W2143777796 @default.
- W4226061570 cites W2143841612 @default.
- W4226061570 cites W2144190078 @default.
- W4226061570 cites W2145144950 @default.
- W4226061570 cites W2164265873 @default.
- W4226061570 cites W2166209782 @default.
- W4226061570 cites W2224656683 @default.
- W4226061570 cites W2259258150 @default.
- W4226061570 cites W2259496665 @default.
- W4226061570 cites W2262330054 @default.
- W4226061570 cites W2517088688 @default.
- W4226061570 cites W2531011640 @default.
- W4226061570 cites W2549009399 @default.
- W4226061570 cites W2553776454 @default.
- W4226061570 cites W2555251529 @default.
- W4226061570 cites W2567027391 @default.
- W4226061570 cites W2572551054 @default.
- W4226061570 cites W2739778494 @default.
- W4226061570 cites W2751128104 @default.
- W4226061570 cites W2753747201 @default.
- W4226061570 cites W2757788196 @default.
- W4226061570 cites W2760979956 @default.
- W4226061570 cites W2761145411 @default.
- W4226061570 cites W2762906919 @default.
- W4226061570 cites W2765228625 @default.
- W4226061570 cites W2767008704 @default.
- W4226061570 cites W2768799378 @default.
- W4226061570 cites W2784207435 @default.
- W4226061570 cites W2796803893 @default.
- W4226061570 cites W2801072950 @default.
- W4226061570 cites W2801440610 @default.
- W4226061570 cites W2808386728 @default.
- W4226061570 cites W2808601843 @default.
- W4226061570 cites W2809035682 @default.
- W4226061570 cites W2887193235 @default.
- W4226061570 cites W2887554246 @default.
- W4226061570 cites W2889513832 @default.
- W4226061570 cites W2896269751 @default.
- W4226061570 cites W2897037806 @default.
- W4226061570 cites W2898338982 @default.
- W4226061570 cites W2907796140 @default.
- W4226061570 cites W2922847497 @default.
- W4226061570 cites W2923680513 @default.
- W4226061570 cites W2940732275 @default.
- W4226061570 cites W2944864099 @default.
- W4226061570 cites W2948451181 @default.
- W4226061570 cites W2949004447 @default.
- W4226061570 cites W2951546814 @default.
- W4226061570 cites W2954197440 @default.
- W4226061570 cites W2954678774 @default.
- W4226061570 cites W2958739722 @default.
- W4226061570 cites W2967398295 @default.
- W4226061570 cites W2969617932 @default.
- W4226061570 cites W2970045605 @default.
- W4226061570 cites W2972666844 @default.
- W4226061570 cites W2979794229 @default.
- W4226061570 cites W2979978196 @default.
- W4226061570 cites W2984153037 @default.
- W4226061570 cites W2991326939 @default.
- W4226061570 cites W2998757248 @default.
- W4226061570 cites W3000944610 @default.
- W4226061570 cites W3008782631 @default.
- W4226061570 cites W3016638589 @default.
- W4226061570 cites W3024321726 @default.
- W4226061570 cites W3027118763 @default.
- W4226061570 cites W3028823705 @default.
- W4226061570 cites W3035326193 @default.