FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226088501> ?p ?o ?g. }

• W4226088501 abstract "Neonatal sepsis is still a major cause of death and morbidity in newborns all over the world. Despite substantial developments in diagnosis, treatments, and prevention strategies, sepsis remains a common problem in clinical practice, particularly in low-resource countries.A retrospective cohort study of 238 neonates with positive blood culture-proven sepsis (in Muhimbili National Hospital) was conducted from January 2019 to December 2020. The outcomes of hospitalization were survival and death.In total, 45.4% mortality resulted from 238 neonates who had sepsis exclusively based on blood culture positivity. A significant association was found between very low birth weight (VLBW), hyperglycemia, mechanical ventilation, and high neonatal mortality. Among the different clinical presentations of neonatal sepsis, lethargy, vomiting, and respiratory distress were found to be frequently associated with neonatal mortality. Furthermore, sepsis with Gram-negative bacteria and early-onset sepsis were also associated with high neonatal mortality. Of the 108 neonatal deaths, the largest proportion (40%) was observed with Staphylococcus aureus, and the remaining 38% was caused by Klebsiella, 14% by Escherichia coli, 5% by Pseudomonas, 4% by Acinetobacter, and 2% by Streptococcus. No neonatal deaths from Serratia infection were observed. The overall resistance of isolated organisms to the recommended first-line antibiotics was 84% for ampicillin and 71.3% for gentamicin. The resistance pattern for the recommended second-line antibiotics was 76.2% for ceftriaxone, 35.9% for vancomycin, and 17.5% for amikacin.VLBW, early-onset sepsis, clinical and laboratory parameters like lethargy, vomiting, and hyperglycemia, sepsis with Gram-negative bacteria, and being on mechanical ventilation are strong predictors of death in neonatal sepsis. In addition, this study discovered extraordinarily high resistance to conventional antibiotics. These findings give light on the crucial aspects to consider in preventing this disease and poor outcomes." @default.
• W4226088501 created "2022-05-05" @default.
• W4226088501 creator A5018211967 @default.
• W4226088501 creator A5020841128 @default.
• W4226088501 creator A5021159141 @default.
• W4226088501 creator A5040215317 @default.
• W4226088501 creator A5074229609 @default.
• W4226088501 creator A5076701737 @default.
• W4226088501 creator A5079477829 @default.
• W4226088501 date "2022-04-05" @default.
• W4226088501 modified "2023-10-15" @default.
• W4226088501 title "Bacteriological Profile and Predictors of Death Among Neonates With Blood Culture-Proven Sepsis in a National Hospital in Tanzania—A Retrospective Cohort Study" @default.
• W4226088501 cites W1573465157 @default.
• W4226088501 cites W1606629335 @default.
• W4226088501 cites W1832313362 @default.
• W4226088501 cites W1968265355 @default.
• W4226088501 cites W1969317219 @default.
• W4226088501 cites W1981531221 @default.
• W4226088501 cites W1983038970 @default.
• W4226088501 cites W1986365878 @default.
• W4226088501 cites W2017046795 @default.
• W4226088501 cites W2031056779 @default.
• W4226088501 cites W2060640511 @default.
• W4226088501 cites W2080171075 @default.
• W4226088501 cites W2083831523 @default.
• W4226088501 cites W2105813932 @default.
• W4226088501 cites W2114278903 @default.
• W4226088501 cites W2120094753 @default.
• W4226088501 cites W2131053905 @default.
• W4226088501 cites W2141964465 @default.
• W4226088501 cites W2144582134 @default.
• W4226088501 cites W2180752973 @default.
• W4226088501 cites W2291824348 @default.
• W4226088501 cites W2341503511 @default.
• W4226088501 cites W2444092801 @default.
• W4226088501 cites W2924803863 @default.
• W4226088501 cites W2965441658 @default.
• W4226088501 cites W2978864793 @default.
• W4226088501 cites W2990046973 @default.
• W4226088501 cites W3048874793 @default.
• W4226088501 cites W3082746234 @default.
• W4226088501 cites W3088227330 @default.
• W4226088501 cites W3088677895 @default.
• W4226088501 cites W3126517187 @default.
• W4226088501 cites W3185623368 @default.
• W4226088501 cites W3205650606 @default.
• W4226088501 doi "https://doi.org/10.3389/fped.2022.797208" @default.
• W4226088501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35450105" @default.
• W4226088501 hasPublicationYear "2022" @default.
• W4226088501 type Work @default.
• W4226088501 citedByCount "1" @default.
• W4226088501 countsByYear W42260885012022 @default.
• W4226088501 crossrefType "journal-article" @default.
• W4226088501 hasAuthorship W4226088501A5018211967 @default.
• W4226088501 hasAuthorship W4226088501A5020841128 @default.
• W4226088501 hasAuthorship W4226088501A5021159141 @default.
• W4226088501 hasAuthorship W4226088501A5040215317 @default.
• W4226088501 hasAuthorship W4226088501A5074229609 @default.
• W4226088501 hasAuthorship W4226088501A5076701737 @default.
• W4226088501 hasAuthorship W4226088501A5079477829 @default.
• W4226088501 hasBestOaLocation W42260885011 @default.
• W4226088501 hasConcept C126322002 @default.
• W4226088501 hasConcept C141071460 @default.
• W4226088501 hasConcept C141983124 @default.
• W4226088501 hasConcept C167135981 @default.
• W4226088501 hasConcept C187212893 @default.
• W4226088501 hasConcept C2775953899 @default.
• W4226088501 hasConcept C2777260799 @default.
• W4226088501 hasConcept C2777427914 @default.
• W4226088501 hasConcept C2778384902 @default.
• W4226088501 hasConcept C2779443120 @default.
• W4226088501 hasConcept C2779473907 @default.
• W4226088501 hasConcept C501593827 @default.
• W4226088501 hasConcept C71924100 @default.
• W4226088501 hasConcept C72563966 @default.
• W4226088501 hasConcept C86803240 @default.
• W4226088501 hasConcept C89423630 @default.
• W4226088501 hasConceptScore W4226088501C126322002 @default.
• W4226088501 hasConceptScore W4226088501C141071460 @default.
• W4226088501 hasConceptScore W4226088501C141983124 @default.
• W4226088501 hasConceptScore W4226088501C167135981 @default.
• W4226088501 hasConceptScore W4226088501C187212893 @default.
• W4226088501 hasConceptScore W4226088501C2775953899 @default.
• W4226088501 hasConceptScore W4226088501C2777260799 @default.
• W4226088501 hasConceptScore W4226088501C2777427914 @default.
• W4226088501 hasConceptScore W4226088501C2778384902 @default.
• W4226088501 hasConceptScore W4226088501C2779443120 @default.
• W4226088501 hasConceptScore W4226088501C2779473907 @default.
• W4226088501 hasConceptScore W4226088501C501593827 @default.
• W4226088501 hasConceptScore W4226088501C71924100 @default.
• W4226088501 hasConceptScore W4226088501C72563966 @default.
• W4226088501 hasConceptScore W4226088501C86803240 @default.
• W4226088501 hasConceptScore W4226088501C89423630 @default.
• W4226088501 hasLocation W42260885011 @default.
• W4226088501 hasLocation W42260885012 @default.
• W4226088501 hasLocation W42260885013 @default.
• W4226088501 hasLocation W42260885014 @default.
• W4226088501 hasOpenAccess W4226088501 @default.
• W4226088501 hasPrimaryLocation W42260885011 @default.
• W4226088501 hasRelatedWork W1995105997 @default.

• next