Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226112883> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4226112883 endingPage "114" @default.
- W4226112883 startingPage "107" @default.
- W4226112883 abstract "For patients with acute large vessel occlusion (ALVO) in the anterior circulation who are able to undergo mechani-cal thrombectomy (MTB) within 4.5 hours, the need for intravenous thrombolysis prior to the intervention remains unclear.Patients who were eligible for intravenous thrombolysis, who presented with ALVO in the anterior circulation, and who started MTB within 4.5 hours were matched at a 1:1 ratio to a thrombectomy alone group or to a bridging therapy group. Patients in the bridging therapy group were administered intravenous alteplase at a standard dose of 0.9 mg/kg. We evaluated the safety and efficacy of the throm-bectomy alone group compared with the bridging therapy group.From December 2020 to September 2021, 60 patients were recruited in the study and completed the trial. The baseline para-meters of patients were similar between the two groups. At the 90-day follow-up, 18 patients (60%) in the thrombectomy alone group versus 18 patients (60%) in the bridging therapy group achieved functional independence (odds ratio [OR]: 1, 95% confidence interval [CI], 0.36-2.81). The successful recanalization (Thrombolysis in Cerebral Infarction [TICI] grade 2b to 3) rates on final angiography were 90% and 86.7%, respectively (OR, 0.72, 95% CI, 0.15-3.55). No significant differences were found between the two groups in the occurrence of symptomatic intracranial hemorrhage or 90-day mortality.Our preliminary results did not show the superiority of thrombectomy alone versus standard bridging therapy in patients with ALVO in the anterior circulation who undergo MTB within 4.5 hours. A larger sample size and other randomized controlled trials remain necessary to validate these results." @default.
- W4226112883 created "2022-05-05" @default.
- W4226112883 creator A5023895948 @default.
- W4226112883 creator A5028339384 @default.
- W4226112883 creator A5031678604 @default.
- W4226112883 creator A5055477087 @default.
- W4226112883 creator A5058100068 @default.
- W4226112883 creator A5080219191 @default.
- W4226112883 creator A5081152873 @default.
- W4226112883 creator A5082256703 @default.
- W4226112883 creator A5088776653 @default.
- W4226112883 date "2022-04-04" @default.
- W4226112883 modified "2023-10-06" @default.
- W4226112883 title "Thrombectomy Alone versus Bridging Therapy in Acute Ischemic Stroke: Preliminary Results of an Experimental Trial." @default.
- W4226112883 doi "https://doi.org/10.7417/ct.2022.2403" @default.
- W4226112883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35385032" @default.
- W4226112883 hasPublicationYear "2022" @default.
- W4226112883 type Work @default.
- W4226112883 citedByCount "6" @default.
- W4226112883 countsByYear W42261128832022 @default.
- W4226112883 countsByYear W42261128832023 @default.
- W4226112883 crossrefType "journal-article" @default.
- W4226112883 hasAuthorship W4226112883A5023895948 @default.
- W4226112883 hasAuthorship W4226112883A5028339384 @default.
- W4226112883 hasAuthorship W4226112883A5031678604 @default.
- W4226112883 hasAuthorship W4226112883A5055477087 @default.
- W4226112883 hasAuthorship W4226112883A5058100068 @default.
- W4226112883 hasAuthorship W4226112883A5080219191 @default.
- W4226112883 hasAuthorship W4226112883A5081152873 @default.
- W4226112883 hasAuthorship W4226112883A5082256703 @default.
- W4226112883 hasAuthorship W4226112883A5088776653 @default.
- W4226112883 hasConcept C126322002 @default.
- W4226112883 hasConcept C127413603 @default.
- W4226112883 hasConcept C141071460 @default.
- W4226112883 hasConcept C156957248 @default.
- W4226112883 hasConcept C168563851 @default.
- W4226112883 hasConcept C174348530 @default.
- W4226112883 hasConcept C2779450755 @default.
- W4226112883 hasConcept C2779581417 @default.
- W4226112883 hasConcept C2780645631 @default.
- W4226112883 hasConcept C31258907 @default.
- W4226112883 hasConcept C41008148 @default.
- W4226112883 hasConcept C42219234 @default.
- W4226112883 hasConcept C44249647 @default.
- W4226112883 hasConcept C500558357 @default.
- W4226112883 hasConcept C541997718 @default.
- W4226112883 hasConcept C71924100 @default.
- W4226112883 hasConcept C78519656 @default.
- W4226112883 hasConceptScore W4226112883C126322002 @default.
- W4226112883 hasConceptScore W4226112883C127413603 @default.
- W4226112883 hasConceptScore W4226112883C141071460 @default.
- W4226112883 hasConceptScore W4226112883C156957248 @default.
- W4226112883 hasConceptScore W4226112883C168563851 @default.
- W4226112883 hasConceptScore W4226112883C174348530 @default.
- W4226112883 hasConceptScore W4226112883C2779450755 @default.
- W4226112883 hasConceptScore W4226112883C2779581417 @default.
- W4226112883 hasConceptScore W4226112883C2780645631 @default.
- W4226112883 hasConceptScore W4226112883C31258907 @default.
- W4226112883 hasConceptScore W4226112883C41008148 @default.
- W4226112883 hasConceptScore W4226112883C42219234 @default.
- W4226112883 hasConceptScore W4226112883C44249647 @default.
- W4226112883 hasConceptScore W4226112883C500558357 @default.
- W4226112883 hasConceptScore W4226112883C541997718 @default.
- W4226112883 hasConceptScore W4226112883C71924100 @default.
- W4226112883 hasConceptScore W4226112883C78519656 @default.
- W4226112883 hasIssue "2" @default.
- W4226112883 hasLocation W42261128831 @default.
- W4226112883 hasOpenAccess W4226112883 @default.
- W4226112883 hasPrimaryLocation W42261128831 @default.
- W4226112883 hasRelatedWork W12435958 @default.
- W4226112883 hasRelatedWork W15231971 @default.
- W4226112883 hasRelatedWork W15311529 @default.
- W4226112883 hasRelatedWork W16684663 @default.
- W4226112883 hasRelatedWork W18033853 @default.
- W4226112883 hasRelatedWork W2110253 @default.
- W4226112883 hasRelatedWork W2126225 @default.
- W4226112883 hasRelatedWork W227432 @default.
- W4226112883 hasRelatedWork W2520082 @default.
- W4226112883 hasRelatedWork W13713547 @default.
- W4226112883 hasVolume "173" @default.
- W4226112883 isParatext "false" @default.
- W4226112883 isRetracted "false" @default.
- W4226112883 workType "article" @default.