FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226135189> ?p ?o ?g. }

• W4226135189 endingPage "198" @default.
• W4226135189 startingPage "192" @default.
• W4226135189 abstract "Idiopathic intracranial hypertension (IIH) is a disorder characterized by elevated intracranial pressure without secondary causes on neuroimaging. IIH typically occurs in young, obese female patients and, when severe, can cause permanent and irreversible vision loss. The association between skull base thinning in patients with intracranial hypertension and obesity has been previously reported; however, no study has reported these findings in IIH. The goal of our study is to determine whether IIH is independently associated with skull base and calvarial thinning.A retrospective, matched case-control study was performed. Each patient diagnosed with IIH (case) was matched with a patient diagnosed with headache (control) by age, gender, and race. Patients were included if they underwent computed tomographic imaging of the head, maxillofacial, or orbits within 3 months of their diagnosis. Exclusion criteria were history of skull base or frontal bone pathology because of surgery or skull trauma, central nervous system infections, or incomplete radiologic data. Patient demographics, medical history, clinical examination, and skull base, calvarial, and zygoma thickness were recorded. Skull base thickness was measured by the height of the auditory canal in the coronal plane. Calvarial thickness was measured just anterior to the foramen rotundum in the coronal plane. Extracranial zygoma thickness was measured and used as an internal imaging control because the zygoma is not subject to intracranial forces.One hundred twenty-six patients were included in the study, 63 cases and 63 controls. Each group comprised 61 female patients (97%), 24 (38%) Caucasian, 23 (37%) black, 1 (2%) Asian, and 15 (24%) others. The average age was 31.5 ± 8.7 years. Patients with IIH were more likely to be obese (n = 60, 95%) compared with the control patients (n = 23, 37%, P < 0.001). All patients with IIH underwent lumbar puncture (LP) with an average opening pressure (OP) of 40.5 ± 15.6 cm H2O, whereas only 13 (20%) controls underwent an LP with a mean OP of 19.5 ± 8.5 cm H2O. There was no statistical difference in mean visual acuity between the IIH and control groups (logMar 0.22 [20/30] ± 0.45 vs logMar 0.09 [20/25] ± 0.30, P = 0.093, respectively). Compared with the controls, patients with IIH were more likely to have headache (97% vs 74%, P = 0.001), pulsatile tinnitus (48% vs 7%, P < 0.001), horizontal binocular diplopia (24% vs 4%, P = 0.006), confrontational visual field deficit (23% vs 2%, P = 0.003), and papilledema (74% vs 0%, P < 0.001). Patients with IIH had thinner skull base and calvarium width compared with the controls (mean skull base thickness 4.17 ± 0.94 mm vs 5.05 ± 1.12 mm, P < 0.001 and mean calvarial width 1.50 ± 0.50 mm vs 1.71 ± 0.61 mm, P = 0.024). Zygoma thickness was similar in both groups (mean zygoma thickness 1.18 ± 0.30 mm in the IIH group vs 1.26 ± 0.35 mm in the control group, P = 0.105). In a subgroup analysis controlling for obesity (body mass index >30 kg/m2), there was no statistically significant difference in skull base, calvarial, or zygoma thickness between obese and nonobese patients.Patients with IIH have thinner mean skull base and calvarial thickness compared with the controls. There was no difference in the mean extracranial zygoma thickness, which was the internal imaging control. Contrary to previous reports, we did not find an association between obesity and skull base or calvarial thinning. These findings suggest that IIH is associated with skull base and calvarial thinning." @default.
• W4226135189 created "2022-05-05" @default.
• W4226135189 creator A5011437993 @default.
• W4226135189 creator A5019151104 @default.
• W4226135189 creator A5056132382 @default.
• W4226135189 creator A5069567196 @default.
• W4226135189 creator A5074410855 @default.
• W4226135189 creator A5084283951 @default.
• W4226135189 creator A5088028171 @default.
• W4226135189 date "2022-02-15" @default.
• W4226135189 modified "2023-09-28" @default.
• W4226135189 title "Thinning of the Skull Base and Calvarial Thickness in Patients With Idiopathic Intracranial Hypertension" @default.
• W4226135189 cites W1493841038 @default.
• W4226135189 cites W1996617337 @default.
• W4226135189 cites W2020745093 @default.
• W4226135189 cites W2037391104 @default.
• W4226135189 cites W2047112768 @default.
• W4226135189 cites W2054331751 @default.
• W4226135189 cites W2057023498 @default.
• W4226135189 cites W2062535887 @default.
• W4226135189 cites W2064348565 @default.
• W4226135189 cites W2070817453 @default.
• W4226135189 cites W2082505821 @default.
• W4226135189 cites W2089255087 @default.
• W4226135189 cites W2111279651 @default.
• W4226135189 cites W2117834225 @default.
• W4226135189 cites W2124921930 @default.
• W4226135189 cites W2155919256 @default.
• W4226135189 cites W2163204421 @default.
• W4226135189 cites W2286321394 @default.
• W4226135189 cites W2314631992 @default.
• W4226135189 cites W2321660428 @default.
• W4226135189 cites W2324342507 @default.
• W4226135189 cites W2333343699 @default.
• W4226135189 cites W2407858379 @default.
• W4226135189 cites W2739665591 @default.
• W4226135189 cites W2739872856 @default.
• W4226135189 cites W2801688933 @default.
• W4226135189 cites W2888940186 @default.
• W4226135189 cites W2914482418 @default.
• W4226135189 cites W2916596946 @default.
• W4226135189 cites W2943505734 @default.
• W4226135189 cites W4385966206 @default.
• W4226135189 cites W771923113 @default.
• W4226135189 doi "https://doi.org/10.1097/wno.0000000000001504" @default.
• W4226135189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35195543" @default.
• W4226135189 hasPublicationYear "2022" @default.
• W4226135189 type Work @default.
• W4226135189 citedByCount "1" @default.
• W4226135189 countsByYear W42261351892022 @default.
• W4226135189 crossrefType "journal-article" @default.
• W4226135189 hasAuthorship W4226135189A5011437993 @default.
• W4226135189 hasAuthorship W4226135189A5019151104 @default.
• W4226135189 hasAuthorship W4226135189A5056132382 @default.
• W4226135189 hasAuthorship W4226135189A5069567196 @default.
• W4226135189 hasAuthorship W4226135189A5074410855 @default.
• W4226135189 hasAuthorship W4226135189A5084283951 @default.
• W4226135189 hasAuthorship W4226135189A5088028171 @default.
• W4226135189 hasConcept C126838900 @default.
• W4226135189 hasConcept C13483470 @default.
• W4226135189 hasConcept C141071460 @default.
• W4226135189 hasConcept C2779300802 @default.
• W4226135189 hasConcept C71924100 @default.
• W4226135189 hasConceptScore W4226135189C126838900 @default.
• W4226135189 hasConceptScore W4226135189C13483470 @default.
• W4226135189 hasConceptScore W4226135189C141071460 @default.
• W4226135189 hasConceptScore W4226135189C2779300802 @default.
• W4226135189 hasConceptScore W4226135189C71924100 @default.
• W4226135189 hasIssue "2" @default.
• W4226135189 hasLocation W42261351891 @default.
• W4226135189 hasLocation W42261351892 @default.
• W4226135189 hasOpenAccess W4226135189 @default.
• W4226135189 hasPrimaryLocation W42261351891 @default.
• W4226135189 hasRelatedWork W1586374228 @default.
• W4226135189 hasRelatedWork W2003938723 @default.
• W4226135189 hasRelatedWork W2047967234 @default.
• W4226135189 hasRelatedWork W2118496982 @default.
• W4226135189 hasRelatedWork W2262423180 @default.
• W4226135189 hasRelatedWork W2364998975 @default.
• W4226135189 hasRelatedWork W2369162477 @default.
• W4226135189 hasRelatedWork W2439875401 @default.
• W4226135189 hasRelatedWork W4238867864 @default.
• W4226135189 hasRelatedWork W2525756941 @default.
• W4226135189 hasVolume "42" @default.
• W4226135189 isParatext "false" @default.
• W4226135189 isRetracted "false" @default.
• W4226135189 workType "article" @default.