Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226154285> ?p ?o ?g. }
- W4226154285 abstract "Abstract Abnormal brain network connectivity is strongly implicated in the pathogenesis of schizophrenia. The striatum, consisting of the caudate and putamen, is the major treatment target for antipsychotics, the primary treatments for schizophrenia; however, there are few studies on the functional connectivity (FC) of striatum in drug‐naive early‐onset schizophrenia (EOS) patients. We examined the FC values of the caudate nucleus and putamen with whole brain by resting‐state functional magnetic resonance imaging (RS‐fMRI) and the associations with indices of clinical severity. Patients demonstrated abnormal FC between subregions of the putamen and both the visual network (left middle occipital gyrus) and default mode network (bilateral anterior cingulate, left superior frontal, and right middle frontal gyri). Furthermore, FC between dorsorostral putamen and left superior frontal gyrus correlated with both positive symptom subscore and total score on the Positive and Negative Syndrome Scale (PANSS). These findings demonstrate abnormal FC between the striatum and other brain areas even in the early stages of schizophrenia, supporting neurodevelopmental disruption in disease etiology and expression." @default.
- W4226154285 created "2022-05-05" @default.
- W4226154285 creator A5012166945 @default.
- W4226154285 creator A5013230389 @default.
- W4226154285 creator A5029225084 @default.
- W4226154285 creator A5037774305 @default.
- W4226154285 creator A5040346880 @default.
- W4226154285 creator A5072038316 @default.
- W4226154285 creator A5074951662 @default.
- W4226154285 creator A5086664284 @default.
- W4226154285 creator A5087699676 @default.
- W4226154285 creator A5088424906 @default.
- W4226154285 creator A5088467911 @default.
- W4226154285 date "2022-04-05" @default.
- W4226154285 modified "2023-10-14" @default.
- W4226154285 title "Abnormal functional connectivity of the striatum in first‐episode drug‐naive early‐onset Schizophrenia" @default.
- W4226154285 cites W1518500152 @default.
- W4226154285 cites W1887230920 @default.
- W4226154285 cites W1968578449 @default.
- W4226154285 cites W1977705664 @default.
- W4226154285 cites W1983565062 @default.
- W4226154285 cites W1985578899 @default.
- W4226154285 cites W1990134753 @default.
- W4226154285 cites W1993095049 @default.
- W4226154285 cites W1999984108 @default.
- W4226154285 cites W2005933475 @default.
- W4226154285 cites W2006122360 @default.
- W4226154285 cites W2009158194 @default.
- W4226154285 cites W2009832071 @default.
- W4226154285 cites W2010643559 @default.
- W4226154285 cites W2012007142 @default.
- W4226154285 cites W2020318870 @default.
- W4226154285 cites W2021645796 @default.
- W4226154285 cites W2027079244 @default.
- W4226154285 cites W2036492209 @default.
- W4226154285 cites W2041092145 @default.
- W4226154285 cites W2047016005 @default.
- W4226154285 cites W2047081388 @default.
- W4226154285 cites W2047975465 @default.
- W4226154285 cites W2052644075 @default.
- W4226154285 cites W2057550180 @default.
- W4226154285 cites W2058187841 @default.
- W4226154285 cites W2064598115 @default.
- W4226154285 cites W2065515121 @default.
- W4226154285 cites W2067955720 @default.
- W4226154285 cites W2072522618 @default.
- W4226154285 cites W2082352870 @default.
- W4226154285 cites W2082805280 @default.
- W4226154285 cites W2093972428 @default.
- W4226154285 cites W2099208432 @default.
- W4226154285 cites W2099626510 @default.
- W4226154285 cites W2101270339 @default.
- W4226154285 cites W2102048758 @default.
- W4226154285 cites W2102099319 @default.
- W4226154285 cites W2108053280 @default.
- W4226154285 cites W2111513387 @default.
- W4226154285 cites W2111783629 @default.
- W4226154285 cites W2114008292 @default.
- W4226154285 cites W2115362552 @default.
- W4226154285 cites W2115687188 @default.
- W4226154285 cites W2118156105 @default.
- W4226154285 cites W2119285123 @default.
- W4226154285 cites W2125273564 @default.
- W4226154285 cites W2130419668 @default.
- W4226154285 cites W2132748057 @default.
- W4226154285 cites W2134128653 @default.
- W4226154285 cites W2136787496 @default.
- W4226154285 cites W2140466990 @default.
- W4226154285 cites W2141782996 @default.
- W4226154285 cites W2142565797 @default.
- W4226154285 cites W2145602532 @default.
- W4226154285 cites W2146945149 @default.
- W4226154285 cites W2150857753 @default.
- W4226154285 cites W2154234679 @default.
- W4226154285 cites W2156258459 @default.
- W4226154285 cites W2164121465 @default.
- W4226154285 cites W2165793012 @default.
- W4226154285 cites W2167474156 @default.
- W4226154285 cites W2167641660 @default.
- W4226154285 cites W2235390735 @default.
- W4226154285 cites W2325014163 @default.
- W4226154285 cites W2335980732 @default.
- W4226154285 cites W2550800662 @default.
- W4226154285 cites W2596422753 @default.
- W4226154285 cites W2623715928 @default.
- W4226154285 cites W2738200303 @default.
- W4226154285 cites W2742069286 @default.
- W4226154285 cites W2751277815 @default.
- W4226154285 cites W2756350541 @default.
- W4226154285 cites W2800045146 @default.
- W4226154285 cites W2802696349 @default.
- W4226154285 cites W2898151345 @default.
- W4226154285 cites W2902980792 @default.
- W4226154285 cites W2906423463 @default.
- W4226154285 cites W2906768105 @default.
- W4226154285 cites W2914072031 @default.
- W4226154285 cites W2932763958 @default.
- W4226154285 cites W2971683016 @default.
- W4226154285 cites W2979531381 @default.
- W4226154285 cites W2979615233 @default.