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- W4226174145 endingPage "5344" @default.
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- W4226174145 abstract "Ring size is a critically important parameter in many interlocked molecules as it directly impacts many of the unique molecular motions that they exhibit. Reported herein are studies using one of the largest macrocycles reported to date to synthesize doubly threaded [3]rotaxanes. A large ditopic 46 atom macrocycle containing two 2,6-bis(N-alkyl-benzimidazolyl)pyridine ligands has been used to synthesize several metastable doubly threaded [3]rotaxanes in high yield (65-75% isolated) via metal templating. Macrocycle and linear thread components were synthesized and self-assembled upon addition of iron(ii) ions to form the doubly threaded pseudo[3]rotaxanes that could be subsequently stoppered using azide-alkyne cycloaddition chemistry. Following demetallation with base, these doubly threaded [3]rotaxanes were fully characterized utilizing a variety of NMR spectroscopy, mass spectrometry, size-exclusion chromatography, and all-atom simulation techniques. Critical to the success of accessing a metastable [3]rotaxane with such a large macrocycle was the nature of the stopper group employed. By varying the size of the stopper group it was possible to access metastable [3]rotaxanes with stabilities in deuterated chloroform ranging from a half-life of <1 minute to ca. 6 months at room temperature potentially opening the door to interlocked materials with controllable degradation rates." @default.
- W4226174145 created "2022-05-05" @default.
- W4226174145 creator A5004881644 @default.
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- W4226174145 creator A5085668066 @default.
- W4226174145 date "2022-01-01" @default.
- W4226174145 modified "2023-10-15" @default.
- W4226174145 title "Metastable doubly threaded [3]rotaxanes with a large macrocycle" @default.
- W4226174145 cites W1218594537 @default.
- W4226174145 cites W1458390031 @default.
- W4226174145 cites W1497035718 @default.
- W4226174145 cites W1699899361 @default.
- W4226174145 cites W1965450832 @default.
- W4226174145 cites W1966394760 @default.
- W4226174145 cites W1975401158 @default.
- W4226174145 cites W1978679524 @default.
- W4226174145 cites W1986997934 @default.
- W4226174145 cites W1987588067 @default.
- W4226174145 cites W1995791857 @default.
- W4226174145 cites W1996609698 @default.
- W4226174145 cites W1997119204 @default.
- W4226174145 cites W1997158083 @default.
- W4226174145 cites W1997260045 @default.
- W4226174145 cites W1997756761 @default.
- W4226174145 cites W1999292426 @default.
- W4226174145 cites W2002461122 @default.
- W4226174145 cites W2003610123 @default.
- W4226174145 cites W2004677759 @default.
- W4226174145 cites W2008634896 @default.
- W4226174145 cites W2011301278 @default.
- W4226174145 cites W2016467718 @default.
- W4226174145 cites W2017075886 @default.
- W4226174145 cites W2018046420 @default.
- W4226174145 cites W2021505628 @default.
- W4226174145 cites W2023557482 @default.
- W4226174145 cites W2037888201 @default.
- W4226174145 cites W2040936391 @default.
- W4226174145 cites W2043635577 @default.
- W4226174145 cites W2049077195 @default.
- W4226174145 cites W2050615363 @default.
- W4226174145 cites W2052430446 @default.
- W4226174145 cites W2066395245 @default.
- W4226174145 cites W2072661863 @default.
- W4226174145 cites W2074247928 @default.
- W4226174145 cites W2078050686 @default.
- W4226174145 cites W2084003160 @default.
- W4226174145 cites W2085103363 @default.
- W4226174145 cites W2089074694 @default.
- W4226174145 cites W2090408346 @default.
- W4226174145 cites W2091383063 @default.
- W4226174145 cites W2093454042 @default.
- W4226174145 cites W2106112638 @default.
- W4226174145 cites W2109289761 @default.
- W4226174145 cites W2117755495 @default.
- W4226174145 cites W2128492772 @default.
- W4226174145 cites W2133209145 @default.
- W4226174145 cites W2133286710 @default.
- W4226174145 cites W2145973927 @default.
- W4226174145 cites W2146548812 @default.
- W4226174145 cites W2151430274 @default.
- W4226174145 cites W2163954891 @default.
- W4226174145 cites W2238173725 @default.
- W4226174145 cites W2321902727 @default.
- W4226174145 cites W2323842433 @default.
- W4226174145 cites W2333974921 @default.
- W4226174145 cites W2421244538 @default.
- W4226174145 cites W2424210401 @default.
- W4226174145 cites W2513488291 @default.
- W4226174145 cites W2515235874 @default.
- W4226174145 cites W2554528697 @default.
- W4226174145 cites W2578655848 @default.
- W4226174145 cites W2609612189 @default.
- W4226174145 cites W2616946930 @default.
- W4226174145 cites W2681634415 @default.
- W4226174145 cites W2741722526 @default.
- W4226174145 cites W2744116498 @default.
- W4226174145 cites W2749358101 @default.
- W4226174145 cites W2772063175 @default.
- W4226174145 cites W2789874863 @default.
- W4226174145 cites W2802760394 @default.
- W4226174145 cites W2804123718 @default.
- W4226174145 cites W2912440548 @default.
- W4226174145 cites W2915465765 @default.
- W4226174145 cites W2943838838 @default.
- W4226174145 cites W2968601320 @default.
- W4226174145 cites W2978660911 @default.
- W4226174145 cites W2978930221 @default.
- W4226174145 cites W2980453869 @default.
- W4226174145 cites W2996232687 @default.
- W4226174145 cites W3012205538 @default.
- W4226174145 cites W3024297355 @default.
- W4226174145 cites W3033421763 @default.