Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226184054> ?p ?o ?g. }
- W4226184054 endingPage "107336" @default.
- W4226184054 startingPage "107336" @default.
- W4226184054 abstract "Intracellular pH undertakes critical functions in various biological and pathological processes. It is important to monitor intracellular pH fluctuations for understanding physiological and pathological processes. Here, one aldehyde-bearing cyclometalated iridium(III) complex ([(4-pba)2Ir(dcphen)]PF6, 4-pba = 4-(2-pyridyl) benzaldehyde, dcphen = 4,7-dichloro-1,10-phenanthroline, probe 1) was synthesized and used to track intracellular pH fluctuations. Probe 1 displayed pH-dependent luminescence property in pH range of 1.81–6.81 with an evaluated pKa value of 4.30 in BR buffer-DMSO (v:v = 99:1). An intramolecular hydrogen bonds assisted pH-responsive mechanism was proposed for the pH-responsive behavior of probe 1. Probe 1 was successfully applied for imaging and tracking pH fluctuations in HeLa cells under external stimulation with fast response time, good photostability as well as low cytotoxicity and high cell permeability. This work demonstrates that aldehyde-bearing cyclometalated iridium(III) complex can be used as alternative pH-responsive probe for real-time tracking intracellular pH fluctuations, which provides a strategy for the design of pH-responsive probe in versatile applications." @default.
- W4226184054 created "2022-05-05" @default.
- W4226184054 creator A5014790362 @default.
- W4226184054 creator A5043954606 @default.
- W4226184054 creator A5046141530 @default.
- W4226184054 creator A5052225808 @default.
- W4226184054 creator A5069181363 @default.
- W4226184054 creator A5081933457 @default.
- W4226184054 creator A5089434745 @default.
- W4226184054 creator A5089654039 @default.
- W4226184054 date "2023-02-01" @default.
- W4226184054 modified "2023-10-18" @default.
- W4226184054 title "pH-responsive aldehyde-bearing cyclometalated iridium(III) complex for tracking intracellular pH fluctuations under external stimulation" @default.
- W4226184054 cites W1547300732 @default.
- W4226184054 cites W1928594450 @default.
- W4226184054 cites W1963957340 @default.
- W4226184054 cites W1996588080 @default.
- W4226184054 cites W2004181413 @default.
- W4226184054 cites W2005496979 @default.
- W4226184054 cites W2034773856 @default.
- W4226184054 cites W2048160294 @default.
- W4226184054 cites W2056504784 @default.
- W4226184054 cites W2064076313 @default.
- W4226184054 cites W2066383202 @default.
- W4226184054 cites W2076769172 @default.
- W4226184054 cites W2095099735 @default.
- W4226184054 cites W2116562304 @default.
- W4226184054 cites W2121585421 @default.
- W4226184054 cites W2124512829 @default.
- W4226184054 cites W2141549209 @default.
- W4226184054 cites W2169232755 @default.
- W4226184054 cites W2170198401 @default.
- W4226184054 cites W2282468245 @default.
- W4226184054 cites W2320195876 @default.
- W4226184054 cites W2324281570 @default.
- W4226184054 cites W2331698751 @default.
- W4226184054 cites W2334050254 @default.
- W4226184054 cites W2436176790 @default.
- W4226184054 cites W2477155714 @default.
- W4226184054 cites W2522989562 @default.
- W4226184054 cites W2617380759 @default.
- W4226184054 cites W2744075983 @default.
- W4226184054 cites W2787230068 @default.
- W4226184054 cites W2883265642 @default.
- W4226184054 cites W2947186674 @default.
- W4226184054 cites W2979626688 @default.
- W4226184054 cites W2997728132 @default.
- W4226184054 cites W3010988347 @default.
- W4226184054 cites W3011953166 @default.
- W4226184054 cites W3037300073 @default.
- W4226184054 cites W3041949755 @default.
- W4226184054 cites W3095477672 @default.
- W4226184054 cites W3113121136 @default.
- W4226184054 cites W3125169772 @default.
- W4226184054 cites W3146232224 @default.
- W4226184054 cites W3165663317 @default.
- W4226184054 cites W3171296103 @default.
- W4226184054 cites W3208022895 @default.
- W4226184054 cites W3208099933 @default.
- W4226184054 doi "https://doi.org/10.1016/j.cclet.2022.03.059" @default.
- W4226184054 hasPublicationYear "2023" @default.
- W4226184054 type Work @default.
- W4226184054 citedByCount "4" @default.
- W4226184054 countsByYear W42261840542023 @default.
- W4226184054 crossrefType "journal-article" @default.
- W4226184054 hasAuthorship W4226184054A5014790362 @default.
- W4226184054 hasAuthorship W4226184054A5043954606 @default.
- W4226184054 hasAuthorship W4226184054A5046141530 @default.
- W4226184054 hasAuthorship W4226184054A5052225808 @default.
- W4226184054 hasAuthorship W4226184054A5069181363 @default.
- W4226184054 hasAuthorship W4226184054A5081933457 @default.
- W4226184054 hasAuthorship W4226184054A5089434745 @default.
- W4226184054 hasAuthorship W4226184054A5089654039 @default.
- W4226184054 hasConcept C12554922 @default.
- W4226184054 hasConcept C134897140 @default.
- W4226184054 hasConcept C161790260 @default.
- W4226184054 hasConcept C185592680 @default.
- W4226184054 hasConcept C21951064 @default.
- W4226184054 hasConcept C2779692420 @default.
- W4226184054 hasConcept C2779825165 @default.
- W4226184054 hasConcept C528581852 @default.
- W4226184054 hasConcept C55493867 @default.
- W4226184054 hasConcept C79879829 @default.
- W4226184054 hasConcept C86803240 @default.
- W4226184054 hasConceptScore W4226184054C12554922 @default.
- W4226184054 hasConceptScore W4226184054C134897140 @default.
- W4226184054 hasConceptScore W4226184054C161790260 @default.
- W4226184054 hasConceptScore W4226184054C185592680 @default.
- W4226184054 hasConceptScore W4226184054C21951064 @default.
- W4226184054 hasConceptScore W4226184054C2779692420 @default.
- W4226184054 hasConceptScore W4226184054C2779825165 @default.
- W4226184054 hasConceptScore W4226184054C528581852 @default.
- W4226184054 hasConceptScore W4226184054C55493867 @default.
- W4226184054 hasConceptScore W4226184054C79879829 @default.
- W4226184054 hasConceptScore W4226184054C86803240 @default.
- W4226184054 hasFunder F4320321001 @default.
- W4226184054 hasFunder F4320322529 @default.
- W4226184054 hasFunder F4320328119 @default.