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- W4226186711 abstract "Gonadotropin-releasing hormone (GnRH) analogues have been used in clinical practice for nearly 3 decades. Beginning with GnRH agonists, these agents have been used to treat hormone-dependent disease and to suppress gonadotropin production in assisted reproductive technologies. With the development of GnRH antagonists and especially small-molecule antagonists, our ability to achieve gonadotropin and sex steroid suppression has become increasingly effective and convenient. In this review, we will briefly describe the development of GnRH analogues, review the evolution of orally active small-molecule GnRH antagonists and provide an overview of the expanding role of small-molecule GnRH antagonists in clinical practice." @default.
- W4226186711 created "2022-05-05" @default.
- W4226186711 creator A5046827780 @default.
- W4226186711 creator A5071745363 @default.
- W4226186711 creator A5073212927 @default.
- W4226186711 date "2021-10-21" @default.
- W4226186711 modified "2023-10-16" @default.
- W4226186711 title "Eliminating Hormones With Orally Active Gonadotropin-releasing Hormone Antagonists" @default.
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- W4226186711 doi "https://doi.org/10.1097/grf.0000000000000664" @default.
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