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- W4226189612 abstract "Lymphomas encompass a heterogenous group of malignant neoplasms of lymphoreticular origin. Based on 2017 data reported by the Centers for Disease Control and Prevention (CDC), Hodgkin lymphoma (HL), defined by the presence of Reed-Sternberg cells, accounts for less than 10% of new lymphoma cases with non-Hodgkin lymphoma (NHL) comprising the remainder. Central nervous system (CNS) disease can be present at the time of diagnosis though is more often found at disease relapse. CNS infiltration is more common in aggressive lymphoma subtypes, including lymphoblastic and Burkitt lymphoma, with a CNS relapse rate around 30%–50% and rare in HL. In comparison, diffuse large B-cell lymphoma (DLBCL), the most common form of NHL, has a more variable rate of CNS relapse depending on the presence or absence of high-risk features. Low-risk groups have an approximated CNS relapse rate of 2%–5%, in contrast to high-risk groups with reports of upward of 40% of CNS relapse." @default.
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- W4226189612 date "2022-01-01" @default.
- W4226189612 modified "2023-10-16" @default.
- W4226189612 title "Neurological complications of lymphoma" @default.
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- W4226189612 doi "https://doi.org/10.1016/b978-0-12-821976-8.00004-9" @default.
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