Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226216020> ?p ?o ?g. }
- W4226216020 endingPage "316" @default.
- W4226216020 startingPage "302" @default.
- W4226216020 abstract "Abstract: Mesenchymal stem cells derived from postnatal orofacial tissues can be readily isolated and possess diverse origins, for example, from surgically removed teeth or gingiva. These cells exhibit stem cell properties, strong potential for self-renewal, and show multi-lineage differentiation, and they have therefore been widely employed in stem cell therapy, tissue regeneration, and inflammatory diseases. Among them, stem cells from human exfoliated deciduous teeth [SHED] and their derivatives have manifested wide application in the treatment of diseases because of their outstanding advantages— including convenient access, easy storage, and less immune rejection. Numerous studies have shown that most diseases are closely associated with inflammation and that inflammatory diseases are extremely destructive, can lead to necrosis of organ parenchymal cells, and can deposit excessive extracellular matrix in the tissues. Inflammatory diseases are thus the principal causes of disability and death from many diseases worldwide. SHED and their derivatives not only exhibit the basic characteristics of stem cells but also exhibit some special properties of their own, particularly with regard to their great potential in inhibiting inflammation and tissue regeneration. SHED therapy may provide a new direction for the treatment of inflammation and corresponding tissue defects. In this review, we critically analyze and summarize the latest findings on the behaviors and functions of SHED, serum‑free conditioned medium from SHED [SHED-CM], and extracellular vesicles, especially exosomes, from SHED [SHED-Exos], and discuss their roles and underlying mechanisms in the control of inflammatory diseases, thus further highlighting additional functions for SHED and their derivatives in future therapies." @default.
- W4226216020 created "2022-05-05" @default.
- W4226216020 creator A5042836530 @default.
- W4226216020 creator A5043989664 @default.
- W4226216020 creator A5059128279 @default.
- W4226216020 creator A5083027868 @default.
- W4226216020 creator A5088477939 @default.
- W4226216020 date "2022-08-02" @default.
- W4226216020 modified "2023-10-18" @default.
- W4226216020 title "Efficacy of Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth and their Derivatives in Inflammatory Diseases Therapy" @default.
- W4226216020 cites W125202112 @default.
- W4226216020 cites W1479842253 @default.
- W4226216020 cites W1490526869 @default.
- W4226216020 cites W1543137167 @default.
- W4226216020 cites W1564612499 @default.
- W4226216020 cites W1819323361 @default.
- W4226216020 cites W1827855608 @default.
- W4226216020 cites W1837964383 @default.
- W4226216020 cites W1956428707 @default.
- W4226216020 cites W1983285262 @default.
- W4226216020 cites W1988009177 @default.
- W4226216020 cites W1988477032 @default.
- W4226216020 cites W1992218960 @default.
- W4226216020 cites W2014813902 @default.
- W4226216020 cites W2029007679 @default.
- W4226216020 cites W2032735323 @default.
- W4226216020 cites W2039744729 @default.
- W4226216020 cites W2045183077 @default.
- W4226216020 cites W2046960775 @default.
- W4226216020 cites W2055400697 @default.
- W4226216020 cites W2061898236 @default.
- W4226216020 cites W2062984171 @default.
- W4226216020 cites W2070334783 @default.
- W4226216020 cites W2073136941 @default.
- W4226216020 cites W2074086534 @default.
- W4226216020 cites W2078039193 @default.
- W4226216020 cites W2080137511 @default.
- W4226216020 cites W2081422207 @default.
- W4226216020 cites W2090560933 @default.
- W4226216020 cites W2093868153 @default.
- W4226216020 cites W2097938259 @default.
- W4226216020 cites W2101117814 @default.
- W4226216020 cites W2104544826 @default.
- W4226216020 cites W2107008239 @default.
- W4226216020 cites W2115437022 @default.
- W4226216020 cites W2116864112 @default.
- W4226216020 cites W2121725913 @default.
- W4226216020 cites W2121776449 @default.
- W4226216020 cites W2123165278 @default.
- W4226216020 cites W2125247008 @default.
- W4226216020 cites W2127517948 @default.
- W4226216020 cites W2136182332 @default.
- W4226216020 cites W2138704758 @default.
- W4226216020 cites W2142072238 @default.
- W4226216020 cites W2152938273 @default.
- W4226216020 cites W2155678564 @default.
- W4226216020 cites W2166182346 @default.
- W4226216020 cites W2167056256 @default.
- W4226216020 cites W2168044601 @default.
- W4226216020 cites W2168864326 @default.
- W4226216020 cites W2173236698 @default.
- W4226216020 cites W2218688166 @default.
- W4226216020 cites W2281134225 @default.
- W4226216020 cites W2337598380 @default.
- W4226216020 cites W2342859699 @default.
- W4226216020 cites W2402512269 @default.
- W4226216020 cites W2407236477 @default.
- W4226216020 cites W2411636592 @default.
- W4226216020 cites W2412751446 @default.
- W4226216020 cites W2419224960 @default.
- W4226216020 cites W2471224732 @default.
- W4226216020 cites W2472248420 @default.
- W4226216020 cites W2493500545 @default.
- W4226216020 cites W2518290087 @default.
- W4226216020 cites W2551095519 @default.
- W4226216020 cites W2567639438 @default.
- W4226216020 cites W2586982562 @default.
- W4226216020 cites W2592326051 @default.
- W4226216020 cites W2746710261 @default.
- W4226216020 cites W2753593979 @default.
- W4226216020 cites W2758143011 @default.
- W4226216020 cites W2767698366 @default.
- W4226216020 cites W2789327010 @default.
- W4226216020 cites W2795267728 @default.
- W4226216020 cites W2796313087 @default.
- W4226216020 cites W2806414351 @default.
- W4226216020 cites W2888250189 @default.
- W4226216020 cites W2889559822 @default.
- W4226216020 cites W2890324251 @default.
- W4226216020 cites W2890650452 @default.
- W4226216020 cites W2891286058 @default.
- W4226216020 cites W2893835498 @default.
- W4226216020 cites W2899011481 @default.
- W4226216020 cites W2899390288 @default.
- W4226216020 cites W2904596861 @default.
- W4226216020 cites W2916832663 @default.
- W4226216020 cites W2930670575 @default.
- W4226216020 cites W2936596103 @default.