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- W4226336651 abstract "Abstrtact A series of 2,2-difluoro-2-arylethylamines was synthesized as fluorinated analogs of octopamine and noradrenaline with the expectation of bioisosteric OH/F exchanges. The syntheses of these compounds were performed by a Suzuki–Miyaura cross-coupling reaction of 4-(bromodifluoroacetyl)morpholine with aryl boronic acids to produce the intermediate 2,2-difluoro-2-arylacetamides, followed by transformation of difluoroacetamide to difluoroethylamine." @default.
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- W4226336651 date "2022-01-01" @default.
- W4226336651 modified "2023-09-26" @default.
- W4226336651 title "Synthesis of 2,2-difluoro-2-arylethylamines as fluorinated analogs of octopamine and noradrenaline" @default.
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- W4226336651 doi "https://doi.org/10.1515/hc-2022-0005" @default.
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