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- W4226356044 abstract "Major histocompatibility complex (MHC) gene family found in various vertebrates comprises three major subfamilies present on the chromosome no. 6. MHC class III genes are located amid MHC classes II and I. However, MHC class I glycoproteins are placed toward the exterior of somatic cells, and MHC II glycoproteins are present primarily on the exterior of specific antigen-presenting cells including macrophages, dendritic cells, and B cells. The peptide-binding region is formed by extracellular domains in both classes of MHC. MHC class I regulates the appearance of an antigen to CD8 + cytotoxic T lymphocytes mainly derived from intracellular sources (endogenous), whereas MHC class II molecules are extremely useful in presenting peptide to CD4+ helper T (TH) cells derived primarily from extracellular sources (endogenous)." @default.
- W4226356044 created "2022-05-05" @default.
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- W4226356044 date "2022-01-01" @default.
- W4226356044 modified "2023-09-26" @default.
- W4226356044 title "Immunognetics: a tool for the identification of novel therapeutic targets in immune disorders" @default.
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- W4226356044 doi "https://doi.org/10.1016/b978-0-323-90250-2.00015-7" @default.
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