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- W4226366924 abstract "The aim of the research. To identify the features of the onset of type-1 diabetes in children and adolescents residing in the territory of a closed city through studying the following manifestations: medical history characteristics, the gender composition and age of patients, the season of the appearance of the initial symptoms as well as clinical manifestations and indicators of carbohydrate metabolism during the initial visit to an endocrinologist. Material and methods. While carrying out the work, the data of the regional registry of diabetes mellitus for the past ten years were studied as well as the information from outpatient records of children and adolescents with type-1 diabetes living in a closed territorial administrative unit in the Krasnoyarsk Territory. Anamnestic and clinical laboratory data were analysed, a comparative analysis with similar data of children in the Krasnoyarsk Territory and Russia was carried out. Results. The study revealed approximately the same quantity of sick children of both genders. The onset of the disease was more oft en noted in the spring-autumn period, the trigger mechanism was viral infection in the overwhelming number of cases. At the moment of manifestation, the bulk of the children had harmonious physical development, the indicators of carbohydrate metabolism indicated significant decompensation. Conclusion. The article presents features of the course of the type-1 diabetes manifestation period in the studied cohort in relation to the age groups of children and the disease onset seasonality. For a broader understanding of the features of the type-1 diabetes onset in children and adolescents living in a closed city, it is necessary to continue research using data on the child population living in similar conditions." @default.
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- W4226366924 date "2022-01-01" @default.
- W4226366924 modified "2023-09-26" @default.
- W4226366924 title "Peculiarities of diabetes mellitus manifestation in children (according to the local register of closed administrative-territorial entities in the Krasnoyarsk Territory)" @default.
- W4226366924 doi "https://doi.org/10.20333/25000136-2022-1-88-94" @default.
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