Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226424463> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4226424463 abstract "The Cachrys genus (Apiaceae) is widely distributed in the Mediterranean Basin. Previous studies have highlighted the photobiological properties of different Cachrys species, such as C. pungens Jan, C. libanotis L. and C. sicula L. Based on these previous promising results, and in order to continue exploring such an interesting genus, the aim of this study was to evaluate the photocytotoxic activity of extracts from Cachrys ferulacea (L.) Calest. Aerial parts were collected in Calabria (southern Italy) and extracted through three different techniques: traditional maceration, supercritical CO2 and pressurized cyclic solid–liquid (PCSL) extraction using Naviglio extractor®. The phytochemical composition was assessed with gas chromatography–mass spectrometry (GC–MS) and the photocytotoxic potential of samples was evaluated on a UVA-irradiated C32 melanoma cell line. The apoptotic responses on treated cells were also assessed. Furthermore, the phenolic and flavonoid contents and the in vitro antioxidant activity were also estimated. Different coumarins were identified and quantified. All the extracts affected cell viability in a concentration-dependent manner after irradiation with UVA light for 1 h at a dose of 1.08 J/cm2. Samples obtained through supercritical CO2 extraction showed the highest activity, with an IC50 value equal to 4.91 μg/mL. This study could provide a starting point for further research focusing on new photosensitizing agents useful in cancer photochemotherapy." @default.
- W4226424463 created "2022-05-05" @default.
- W4226424463 creator A5027465837 @default.
- W4226424463 creator A5033880599 @default.
- W4226424463 creator A5036522666 @default.
- W4226424463 creator A5047748434 @default.
- W4226424463 creator A5049200791 @default.
- W4226424463 creator A5067301044 @default.
- W4226424463 creator A5074995984 @default.
- W4226424463 date "2021-12-01" @default.
- W4226424463 modified "2023-09-26" @default.
- W4226424463 title "Cachrys ferulacea (L.) Calest. Extracts as Natural Photosensitizers: An In Vitro Photobiological Study" @default.
- W4226424463 cites W2077298269 @default.
- W4226424463 cites W2092827417 @default.
- W4226424463 cites W2096403123 @default.
- W4226424463 cites W2162262059 @default.
- W4226424463 cites W2620923762 @default.
- W4226424463 cites W2789502557 @default.
- W4226424463 cites W2896252391 @default.
- W4226424463 cites W2939884506 @default.
- W4226424463 cites W2988302131 @default.
- W4226424463 cites W2994650489 @default.
- W4226424463 cites W3004766621 @default.
- W4226424463 cites W3042754637 @default.
- W4226424463 cites W3119400081 @default.
- W4226424463 doi "https://doi.org/10.3390/iecps2021-11998" @default.
- W4226424463 hasPublicationYear "2021" @default.
- W4226424463 type Work @default.
- W4226424463 citedByCount "0" @default.
- W4226424463 crossrefType "proceedings-article" @default.
- W4226424463 hasAuthorship W4226424463A5027465837 @default.
- W4226424463 hasAuthorship W4226424463A5033880599 @default.
- W4226424463 hasAuthorship W4226424463A5036522666 @default.
- W4226424463 hasAuthorship W4226424463A5047748434 @default.
- W4226424463 hasAuthorship W4226424463A5049200791 @default.
- W4226424463 hasAuthorship W4226424463A5067301044 @default.
- W4226424463 hasAuthorship W4226424463A5074995984 @default.
- W4226424463 hasBestOaLocation W42264244631 @default.
- W4226424463 hasConcept C159985019 @default.
- W4226424463 hasConcept C185592680 @default.
- W4226424463 hasConcept C192562407 @default.
- W4226424463 hasConcept C195475562 @default.
- W4226424463 hasConcept C199919908 @default.
- W4226424463 hasConcept C202751555 @default.
- W4226424463 hasConcept C43617362 @default.
- W4226424463 hasConcept C4725764 @default.
- W4226424463 hasConcept C55493867 @default.
- W4226424463 hasConcept C556039675 @default.
- W4226424463 hasConcept C59822182 @default.
- W4226424463 hasConcept C71924100 @default.
- W4226424463 hasConcept C74940592 @default.
- W4226424463 hasConcept C86803240 @default.
- W4226424463 hasConceptScore W4226424463C159985019 @default.
- W4226424463 hasConceptScore W4226424463C185592680 @default.
- W4226424463 hasConceptScore W4226424463C192562407 @default.
- W4226424463 hasConceptScore W4226424463C195475562 @default.
- W4226424463 hasConceptScore W4226424463C199919908 @default.
- W4226424463 hasConceptScore W4226424463C202751555 @default.
- W4226424463 hasConceptScore W4226424463C43617362 @default.
- W4226424463 hasConceptScore W4226424463C4725764 @default.
- W4226424463 hasConceptScore W4226424463C55493867 @default.
- W4226424463 hasConceptScore W4226424463C556039675 @default.
- W4226424463 hasConceptScore W4226424463C59822182 @default.
- W4226424463 hasConceptScore W4226424463C71924100 @default.
- W4226424463 hasConceptScore W4226424463C74940592 @default.
- W4226424463 hasConceptScore W4226424463C86803240 @default.
- W4226424463 hasLocation W42264244631 @default.
- W4226424463 hasOpenAccess W4226424463 @default.
- W4226424463 hasPrimaryLocation W42264244631 @default.
- W4226424463 hasRelatedWork W2246823946 @default.
- W4226424463 hasRelatedWork W2270498058 @default.
- W4226424463 hasRelatedWork W2556792895 @default.
- W4226424463 hasRelatedWork W2735577872 @default.
- W4226424463 hasRelatedWork W2788261216 @default.
- W4226424463 hasRelatedWork W2885904309 @default.
- W4226424463 hasRelatedWork W2904783307 @default.
- W4226424463 hasRelatedWork W3038873168 @default.
- W4226424463 hasRelatedWork W3099394675 @default.
- W4226424463 hasRelatedWork W3134710240 @default.
- W4226424463 isParatext "false" @default.
- W4226424463 isRetracted "false" @default.
- W4226424463 workType "article" @default.