Matches in SemOpenAlex for { <https://semopenalex.org/work/W4226455429> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4226455429 endingPage "83" @default.
- W4226455429 startingPage "79" @default.
- W4226455429 abstract "The electroencephalogram (EEG) may be useful for monitoring anesthetic depth and avoiding overdose. We aimed to characterize EEG-recorded brain oscillations during increasing depth of anesthesia in a real-life surgical scenario. We hypothesized that alpha power and coherency will diminish as propofol dose increases between loss of consciousness (LOC) and an EEG burst suppression (BS) pattern.This nonrandomized dose-response clinical trial with concurrent control included EEG monitoring in 16 patients receiving slowly increasing doses of propofol. We assessed 3 intraoperative EEG segments (LOC, middle-dose, and BS) with spectral analysis.Alpha band power diminished with each step increase in propofol dose. Average alpha power and average delta power during the BS step (-1.4±3.8 and 6.2±3.1 dB, respectively) were significantly lower than during the LOC step (2.8±2.6; P=0.004 and 10.1±5.2 dB; P=0.03, respectively). Peak alpha power was significantly higher during the LOC (5.4±2.6 dB) compared with middle-dose (2.6±3.6; P=0.04) and BS (0.7±3.2; P=0.0002) steps. In addition, as propofol dose increased, alpha band coherence between the F7 and F8 electrodes decreased, whereas delta band coherence exhibited a biphasic response (initial increase between LOC and middle-dose steps and decrease between middle-dose and BS steps).We report compelling data regarding EEG patterns associated with increases in propofol dose. This information may more accurately define therapeutic windows for anesthesia and provide insights into brain dynamics that are sequentially affected by increased anesthetic doses." @default.
- W4226455429 created "2022-05-05" @default.
- W4226455429 creator A5004287385 @default.
- W4226455429 creator A5025279825 @default.
- W4226455429 creator A5053873808 @default.
- W4226455429 creator A5079459676 @default.
- W4226455429 date "2020-10-13" @default.
- W4226455429 modified "2023-09-27" @default.
- W4226455429 title "Electroencephalographic Alpha and Delta Oscillation Dynamics in Response to Increasing Doses of Propofol" @default.
- W4226455429 cites W1977518154 @default.
- W4226455429 cites W1978956684 @default.
- W4226455429 cites W2002996884 @default.
- W4226455429 cites W2073182347 @default.
- W4226455429 cites W2106877932 @default.
- W4226455429 cites W2112727871 @default.
- W4226455429 cites W2151442629 @default.
- W4226455429 cites W2160419313 @default.
- W4226455429 cites W2168126101 @default.
- W4226455429 cites W2255398506 @default.
- W4226455429 cites W2589028660 @default.
- W4226455429 cites W2685565572 @default.
- W4226455429 cites W2773438964 @default.
- W4226455429 cites W2919331341 @default.
- W4226455429 cites W2971570110 @default.
- W4226455429 cites W2981152026 @default.
- W4226455429 cites W2983229964 @default.
- W4226455429 cites W3025945084 @default.
- W4226455429 doi "https://doi.org/10.1097/ana.0000000000000733" @default.
- W4226455429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33060553" @default.
- W4226455429 hasPublicationYear "2020" @default.
- W4226455429 type Work @default.
- W4226455429 citedByCount "4" @default.
- W4226455429 countsByYear W42264554292021 @default.
- W4226455429 countsByYear W42264554292022 @default.
- W4226455429 countsByYear W42264554292023 @default.
- W4226455429 crossrefType "journal-article" @default.
- W4226455429 hasAuthorship W4226455429A5004287385 @default.
- W4226455429 hasAuthorship W4226455429A5025279825 @default.
- W4226455429 hasAuthorship W4226455429A5053873808 @default.
- W4226455429 hasAuthorship W4226455429A5079459676 @default.
- W4226455429 hasConcept C118552586 @default.
- W4226455429 hasConcept C141071460 @default.
- W4226455429 hasConcept C167639399 @default.
- W4226455429 hasConcept C2775944032 @default.
- W4226455429 hasConcept C2776277131 @default.
- W4226455429 hasConcept C2778162923 @default.
- W4226455429 hasConcept C42219234 @default.
- W4226455429 hasConcept C49453240 @default.
- W4226455429 hasConcept C522805319 @default.
- W4226455429 hasConcept C64943373 @default.
- W4226455429 hasConcept C71924100 @default.
- W4226455429 hasConceptScore W4226455429C118552586 @default.
- W4226455429 hasConceptScore W4226455429C141071460 @default.
- W4226455429 hasConceptScore W4226455429C167639399 @default.
- W4226455429 hasConceptScore W4226455429C2775944032 @default.
- W4226455429 hasConceptScore W4226455429C2776277131 @default.
- W4226455429 hasConceptScore W4226455429C2778162923 @default.
- W4226455429 hasConceptScore W4226455429C42219234 @default.
- W4226455429 hasConceptScore W4226455429C49453240 @default.
- W4226455429 hasConceptScore W4226455429C522805319 @default.
- W4226455429 hasConceptScore W4226455429C64943373 @default.
- W4226455429 hasConceptScore W4226455429C71924100 @default.
- W4226455429 hasIssue "1" @default.
- W4226455429 hasLocation W42264554291 @default.
- W4226455429 hasLocation W42264554292 @default.
- W4226455429 hasOpenAccess W4226455429 @default.
- W4226455429 hasPrimaryLocation W42264554291 @default.
- W4226455429 hasRelatedWork W1967544367 @default.
- W4226455429 hasRelatedWork W1986278074 @default.
- W4226455429 hasRelatedWork W2000542353 @default.
- W4226455429 hasRelatedWork W2009482244 @default.
- W4226455429 hasRelatedWork W2024821917 @default.
- W4226455429 hasRelatedWork W2273254331 @default.
- W4226455429 hasRelatedWork W2367029572 @default.
- W4226455429 hasRelatedWork W2965586106 @default.
- W4226455429 hasRelatedWork W3117223433 @default.
- W4226455429 hasRelatedWork W2413521946 @default.
- W4226455429 hasVolume "34" @default.
- W4226455429 isParatext "false" @default.
- W4226455429 isRetracted "false" @default.
- W4226455429 workType "article" @default.