Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229008604> ?p ?o ?g. }
- W4229008604 abstract "A Ru(bpy)3 Cl2 photocatalyst is applied to the rapid trans to cis isomerization of a range of alkene-containing pharmacological agents, including combretastatin A-4 (CA-4), a clinical candidate in oncology, and resveratrol derivatives, switching their configuration from inactive substances to potent cytotoxic agents. Selective in cellulo activation of the CA-4 analog Res-3M is demonstrated, along with its potent cytotoxicity and inhibition of microtubule dynamics." @default.
- W4229008604 created "2022-05-08" @default.
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- W4229008604 date "2022-05-20" @default.
- W4229008604 modified "2023-10-16" @default.
- W4229008604 title "Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization" @default.
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- W4229008604 doi "https://doi.org/10.1002/anie.202203390" @default.
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