Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229014242> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4229014242 endingPage "6" @default.
- W4229014242 startingPage "1" @default.
- W4229014242 abstract "β-Thalassemia has a very wide clinical variation, depending on the severity of the patient's condition. Individuals with β-thalassemia traits are usually asymptomatic; however, laboratory examination will show mild anemia with microcytic hypochromic erythrocytes morphology with wide variation depending on the genotype. This study was conducted to determine the reference value of hematological parameters and hemoglobin (Hb) analysis based on the phenotype of β-thalassemia (β0 and β+) and determine the differences of hematological characteristics between the two phenotypes.This cross-sectional study was conducted by evaluating the hematological parameters and Hb analysis of the β-thalassemia trait in the family of thalassemia patient population. The subjects were divided into β0 and β+. The subject with normal Hb analysis with or without iron deficiency was excluded.A total of 203 subjects with thalassemia traits were included from the families of thalassemia patients, consisting of 101 subjects with β0-thalassemia, 82 subjects with β+-thalassemia, and the mutation had not been found in 20 subjects. There was a relationship in the mean/median of hematological parameters, HbA2 and HbF, between β0-thalassemia and β+-thalassemia (P < 0.05). ROC for each hematological parameter, HbA2 and HbF, showed that the highest diagnostic value based on the area under the curve was mean corpuscular hemoglobin (MCH) (0.900) and mean corpuscular volume (MCV) (0.898). The cutoff point of MCH for β0-thalassemia trait was ≤20.5 pg (sensitivity 85%, specificity 90%) and MCV was ≤66.8 fL (sensitivity 87%, specificity 87%).MCH values can be used as a screening tool for predicting β0-thalassemia in the relatives of thalassemia patients in the South Sumatra population." @default.
- W4229014242 created "2022-05-08" @default.
- W4229014242 creator A5033836737 @default.
- W4229014242 creator A5041632474 @default.
- W4229014242 creator A5064298368 @default.
- W4229014242 creator A5067349056 @default.
- W4229014242 creator A5076290310 @default.
- W4229014242 creator A5085155602 @default.
- W4229014242 date "2022-05-05" @default.
- W4229014242 modified "2023-09-30" @default.
- W4229014242 title "Hematological Parameters in Individuals with Beta Thalassemia Trait in South Sumatra, Indonesia" @default.
- W4229014242 cites W132484415 @default.
- W4229014242 cites W1524228829 @default.
- W4229014242 cites W2116767791 @default.
- W4229014242 cites W2167575052 @default.
- W4229014242 cites W2396223290 @default.
- W4229014242 cites W2400990757 @default.
- W4229014242 cites W2889955206 @default.
- W4229014242 cites W2933379641 @default.
- W4229014242 cites W2963294683 @default.
- W4229014242 cites W3083542131 @default.
- W4229014242 cites W3092052083 @default.
- W4229014242 cites W4211225058 @default.
- W4229014242 doi "https://doi.org/10.1155/2022/3572986" @default.
- W4229014242 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35573052" @default.
- W4229014242 hasPublicationYear "2022" @default.
- W4229014242 type Work @default.
- W4229014242 citedByCount "4" @default.
- W4229014242 countsByYear W42290142422022 @default.
- W4229014242 countsByYear W42290142422023 @default.
- W4229014242 crossrefType "journal-article" @default.
- W4229014242 hasAuthorship W4229014242A5033836737 @default.
- W4229014242 hasAuthorship W4229014242A5041632474 @default.
- W4229014242 hasAuthorship W4229014242A5064298368 @default.
- W4229014242 hasAuthorship W4229014242A5067349056 @default.
- W4229014242 hasAuthorship W4229014242A5076290310 @default.
- W4229014242 hasAuthorship W4229014242A5085155602 @default.
- W4229014242 hasBestOaLocation W42290142421 @default.
- W4229014242 hasConcept C104317684 @default.
- W4229014242 hasConcept C126322002 @default.
- W4229014242 hasConcept C135763542 @default.
- W4229014242 hasConcept C187212893 @default.
- W4229014242 hasConcept C2775897519 @default.
- W4229014242 hasConcept C2777799968 @default.
- W4229014242 hasConcept C2777910003 @default.
- W4229014242 hasConcept C2777940137 @default.
- W4229014242 hasConcept C2778248108 @default.
- W4229014242 hasConcept C2778548071 @default.
- W4229014242 hasConcept C2778917026 @default.
- W4229014242 hasConcept C2780554921 @default.
- W4229014242 hasConcept C2781058662 @default.
- W4229014242 hasConcept C54355233 @default.
- W4229014242 hasConcept C71924100 @default.
- W4229014242 hasConcept C78529466 @default.
- W4229014242 hasConcept C86803240 @default.
- W4229014242 hasConcept C90924648 @default.
- W4229014242 hasConceptScore W4229014242C104317684 @default.
- W4229014242 hasConceptScore W4229014242C126322002 @default.
- W4229014242 hasConceptScore W4229014242C135763542 @default.
- W4229014242 hasConceptScore W4229014242C187212893 @default.
- W4229014242 hasConceptScore W4229014242C2775897519 @default.
- W4229014242 hasConceptScore W4229014242C2777799968 @default.
- W4229014242 hasConceptScore W4229014242C2777910003 @default.
- W4229014242 hasConceptScore W4229014242C2777940137 @default.
- W4229014242 hasConceptScore W4229014242C2778248108 @default.
- W4229014242 hasConceptScore W4229014242C2778548071 @default.
- W4229014242 hasConceptScore W4229014242C2778917026 @default.
- W4229014242 hasConceptScore W4229014242C2780554921 @default.
- W4229014242 hasConceptScore W4229014242C2781058662 @default.
- W4229014242 hasConceptScore W4229014242C54355233 @default.
- W4229014242 hasConceptScore W4229014242C71924100 @default.
- W4229014242 hasConceptScore W4229014242C78529466 @default.
- W4229014242 hasConceptScore W4229014242C86803240 @default.
- W4229014242 hasConceptScore W4229014242C90924648 @default.
- W4229014242 hasLocation W42290142421 @default.
- W4229014242 hasLocation W42290142422 @default.
- W4229014242 hasLocation W42290142423 @default.
- W4229014242 hasOpenAccess W4229014242 @default.
- W4229014242 hasPrimaryLocation W42290142421 @default.
- W4229014242 hasRelatedWork W2029120019 @default.
- W4229014242 hasRelatedWork W2320291581 @default.
- W4229014242 hasRelatedWork W2386022156 @default.
- W4229014242 hasRelatedWork W3002961163 @default.
- W4229014242 hasRelatedWork W3198609801 @default.
- W4229014242 hasRelatedWork W4205224017 @default.
- W4229014242 hasRelatedWork W4229014242 @default.
- W4229014242 hasRelatedWork W432255942 @default.
- W4229014242 hasRelatedWork W4385153583 @default.
- W4229014242 hasRelatedWork W2889207941 @default.
- W4229014242 hasVolume "2022" @default.
- W4229014242 isParatext "false" @default.
- W4229014242 isRetracted "false" @default.
- W4229014242 workType "article" @default.