FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229015570> ?p ?o ?g. }

• W4229015570 abstract "Background: Biofilm formation is a vital feature of the pathogenesis in filamentous fungi. Objectives: Herein, we investigated in vitro antifungal pattern of biofilm of filamentous species keratitis isolates, and the effect of different concentrations of voriconazole on biofilm morphology changes using scanning electron microscopy. Methods: Here 25 ocular fungal isolates were included (Fusarium solani; (n = 15) and Aspergillus flavus; (n = 10). We determined the biofilm formation of isolates in terms of their susceptibilities to different antifungals on sessile cells. This procedure was performed according to CLSI-M38-3rd. Biofilm morphology changes revealed with scanning electron microscopy (SEM). Results: Twelve F. solani strains displayed the capacity to form biofilms from patients wearing contact lenses, while 8 A. flavus strains were recovered from cornea scrapings of trauma. Itraconazole, posaconazole and natamycin had the maximum activity against biofilms of all tested filamentous strains (MIC ranging from 0.031 - 0.25 µg/mL, 0.031 - 0.25 µg/mL and 2 - 4 µg/mL), respectively. Three F. solani and one A. flavus strains showed the high MIC values against voriconazole (MIC ≥ 1 µg/mL). Posaconazole revealed the lowest MIC values against biofilms of two strains (MIC ranging from 0.031 - 0.25 µg/mL); however, no significant difference was observed for itraconazole (P > 0.05). The efficacy of 16 µg/mL and 4 µg/mL of voriconazole was confirmed for biofilm of F. solani and A. flavus, respectively. The considerable changes in the morphologies of improved biofilms were seen by SEM. Conclusions: For the successful treatment of fungal biofilm infections, it was necessary to have knowledge of the mechanism of action, penetration rates, and therapeutic concentrations of drugs." @default.
• W4229015570 created "2022-05-08" @default.
• W4229015570 creator A5001146682 @default.
• W4229015570 creator A5027941435 @default.
• W4229015570 creator A5027969007 @default.
• W4229015570 creator A5074658386 @default.
• W4229015570 creator A5087602380 @default.
• W4229015570 creator A5088628794 @default.
• W4229015570 date "2022-05-07" @default.
• W4229015570 modified "2023-10-06" @default.
• W4229015570 title "Effect of Voriconazole on Biofilm of Filamentous Species Isolated from Keratitis" @default.
• W4229015570 cites W1592505922 @default.
• W4229015570 cites W170995186 @default.
• W4229015570 cites W1991004042 @default.
• W4229015570 cites W2000975660 @default.
• W4229015570 cites W2001276323 @default.
• W4229015570 cites W2025725036 @default.
• W4229015570 cites W2038410142 @default.
• W4229015570 cites W2043675944 @default.
• W4229015570 cites W2058411824 @default.
• W4229015570 cites W2059111198 @default.
• W4229015570 cites W2116582646 @default.
• W4229015570 cites W2125848302 @default.
• W4229015570 cites W2126025312 @default.
• W4229015570 cites W2133463731 @default.
• W4229015570 cites W2135493487 @default.
• W4229015570 cites W2144386074 @default.
• W4229015570 cites W2151790183 @default.
• W4229015570 cites W2159093932 @default.
• W4229015570 cites W2585392292 @default.
• W4229015570 cites W2741292614 @default.
• W4229015570 cites W2757444754 @default.
• W4229015570 cites W2787413609 @default.
• W4229015570 cites W2910390683 @default.
• W4229015570 cites W2947842910 @default.
• W4229015570 cites W2963829130 @default.
• W4229015570 cites W3014267423 @default.
• W4229015570 cites W4237275920 @default.
• W4229015570 cites W4239515908 @default.
• W4229015570 doi "https://doi.org/10.5812/archcid-122452" @default.
• W4229015570 hasPublicationYear "2022" @default.
• W4229015570 type Work @default.
• W4229015570 citedByCount "0" @default.
• W4229015570 crossrefType "journal-article" @default.
• W4229015570 hasAuthorship W4229015570A5001146682 @default.
• W4229015570 hasAuthorship W4229015570A5027941435 @default.
• W4229015570 hasAuthorship W4229015570A5027969007 @default.
• W4229015570 hasAuthorship W4229015570A5074658386 @default.
• W4229015570 hasAuthorship W4229015570A5087602380 @default.
• W4229015570 hasAuthorship W4229015570A5088628794 @default.
• W4229015570 hasBestOaLocation W42290155701 @default.
• W4229015570 hasConcept C185592680 @default.
• W4229015570 hasConcept C2776079991 @default.
• W4229015570 hasConcept C2777071850 @default.
• W4229015570 hasConcept C2777292910 @default.
• W4229015570 hasConcept C2778342517 @default.
• W4229015570 hasConcept C2778560704 @default.
• W4229015570 hasConcept C2778566413 @default.
• W4229015570 hasConcept C2779117757 @default.
• W4229015570 hasConcept C2779548794 @default.
• W4229015570 hasConcept C2780690907 @default.
• W4229015570 hasConcept C31903555 @default.
• W4229015570 hasConcept C523546767 @default.
• W4229015570 hasConcept C54355233 @default.
• W4229015570 hasConcept C58123911 @default.
• W4229015570 hasConcept C86803240 @default.
• W4229015570 hasConcept C89423630 @default.
• W4229015570 hasConceptScore W4229015570C185592680 @default.
• W4229015570 hasConceptScore W4229015570C2776079991 @default.
• W4229015570 hasConceptScore W4229015570C2777071850 @default.
• W4229015570 hasConceptScore W4229015570C2777292910 @default.
• W4229015570 hasConceptScore W4229015570C2778342517 @default.
• W4229015570 hasConceptScore W4229015570C2778560704 @default.
• W4229015570 hasConceptScore W4229015570C2778566413 @default.
• W4229015570 hasConceptScore W4229015570C2779117757 @default.
• W4229015570 hasConceptScore W4229015570C2779548794 @default.
• W4229015570 hasConceptScore W4229015570C2780690907 @default.
• W4229015570 hasConceptScore W4229015570C31903555 @default.
• W4229015570 hasConceptScore W4229015570C523546767 @default.
• W4229015570 hasConceptScore W4229015570C54355233 @default.
• W4229015570 hasConceptScore W4229015570C58123911 @default.
• W4229015570 hasConceptScore W4229015570C86803240 @default.
• W4229015570 hasConceptScore W4229015570C89423630 @default.
• W4229015570 hasIssue "6" @default.
• W4229015570 hasLocation W42290155701 @default.
• W4229015570 hasOpenAccess W4229015570 @default.
• W4229015570 hasPrimaryLocation W42290155701 @default.
• W4229015570 hasRelatedWork W1175855173 @default.
• W4229015570 hasRelatedWork W1981968855 @default.
• W4229015570 hasRelatedWork W1998209502 @default.
• W4229015570 hasRelatedWork W2042213457 @default.
• W4229015570 hasRelatedWork W2060343335 @default.
• W4229015570 hasRelatedWork W2113040118 @default.
• W4229015570 hasRelatedWork W2612870821 @default.
• W4229015570 hasRelatedWork W2967281330 @default.
• W4229015570 hasRelatedWork W3000299526 @default.
• W4229015570 hasRelatedWork W4229015570 @default.
• W4229015570 hasVolume "16" @default.
• W4229015570 isParatext "false" @default.
• W4229015570 isRetracted "false" @default.

• next