Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229072214> ?p ?o ?g. }
- W4229072214 endingPage "121565" @default.
- W4229072214 startingPage "121565" @default.
- W4229072214 abstract "Cancer cells can reprogram metabolic pathways to facilitate proliferation, metastasis, biosynthesis, and chemoresistance. Metabolic reprogramming is currently considered as a hallmark of tumors and is recognized as a promising therapeutic strategy. The recent progress in nanomedicine has greatly improved the therapeutic effect of conventional therapeutic modalities such as surgical treatment, radiotherapy, chemical drug therapy. However, nanomedicine engineering still fails to achieve satisfactory therapeutic effects due to the metabolic reprogramming of tumor cells. The targeted delivery and development of precise therapeutic strategies are the latest focus in tumor metabolism to design nanomedicines according to the characteristics of cancer metabolic reprogramming. Therefore, this review focuses mainly on metabolic pathways of tumors. Pathways such as glycolysis, aerobic respiration, lipid metabolism, nucleotide metabolism, and glutathione metabolism are reviewed in detail. The latest advances are summarized in the design and combined treatment of smart nanomedicines that can regulate cancer metabolism to provide an emerging cancer therapeutic model. The challenges and future developments of this cancer therapeutic model are discussed in detail to understand as much as possible the prospects of this field. Designing nanomedicine therapy strategies by targeting tumor metabolic characteristics will provide a novel approach for the application of personalized biomedicine of tumors." @default.
- W4229072214 created "2022-05-08" @default.
- W4229072214 creator A5011390933 @default.
- W4229072214 creator A5023395458 @default.
- W4229072214 creator A5039391338 @default.
- W4229072214 creator A5040598031 @default.
- W4229072214 creator A5041997172 @default.
- W4229072214 creator A5042558365 @default.
- W4229072214 creator A5057049857 @default.
- W4229072214 creator A5066415299 @default.
- W4229072214 creator A5076824143 @default.
- W4229072214 creator A5084588564 @default.
- W4229072214 date "2022-07-01" @default.
- W4229072214 modified "2023-10-10" @default.
- W4229072214 title "Advanced nanomedicines for the regulation of cancer metabolism" @default.
- W4229072214 cites W1965773237 @default.
- W4229072214 cites W1969516914 @default.
- W4229072214 cites W1993180174 @default.
- W4229072214 cites W1996311090 @default.
- W4229072214 cites W2008006215 @default.
- W4229072214 cites W2013485244 @default.
- W4229072214 cites W2016177837 @default.
- W4229072214 cites W2021006272 @default.
- W4229072214 cites W2026264997 @default.
- W4229072214 cites W2038974826 @default.
- W4229072214 cites W2045413888 @default.
- W4229072214 cites W2064769568 @default.
- W4229072214 cites W2066379425 @default.
- W4229072214 cites W2068749469 @default.
- W4229072214 cites W2071635152 @default.
- W4229072214 cites W2086971976 @default.
- W4229072214 cites W2099711117 @default.
- W4229072214 cites W2108984461 @default.
- W4229072214 cites W2112645200 @default.
- W4229072214 cites W2118758371 @default.
- W4229072214 cites W2121171143 @default.
- W4229072214 cites W2123049006 @default.
- W4229072214 cites W2125257427 @default.
- W4229072214 cites W2125872855 @default.
- W4229072214 cites W2132904123 @default.
- W4229072214 cites W2143036691 @default.
- W4229072214 cites W2147044753 @default.
- W4229072214 cites W2151684691 @default.
- W4229072214 cites W2153178365 @default.
- W4229072214 cites W2159728029 @default.
- W4229072214 cites W2163288640 @default.
- W4229072214 cites W2165535625 @default.
- W4229072214 cites W2166571334 @default.
- W4229072214 cites W2171636224 @default.
- W4229072214 cites W2239439128 @default.
- W4229072214 cites W2323004650 @default.
- W4229072214 cites W2417259144 @default.
- W4229072214 cites W2511561583 @default.
- W4229072214 cites W2520458702 @default.
- W4229072214 cites W2554956457 @default.
- W4229072214 cites W2561740859 @default.
- W4229072214 cites W2569530200 @default.
- W4229072214 cites W2571556434 @default.
- W4229072214 cites W2620153804 @default.
- W4229072214 cites W2744214070 @default.
- W4229072214 cites W2747084009 @default.
- W4229072214 cites W2747423355 @default.
- W4229072214 cites W2764028271 @default.
- W4229072214 cites W2771639621 @default.
- W4229072214 cites W2788735115 @default.
- W4229072214 cites W2791022934 @default.
- W4229072214 cites W2791161795 @default.
- W4229072214 cites W2792926732 @default.
- W4229072214 cites W2798209291 @default.
- W4229072214 cites W2883440571 @default.
- W4229072214 cites W2887207606 @default.
- W4229072214 cites W2887864019 @default.
- W4229072214 cites W2893234597 @default.
- W4229072214 cites W2896774678 @default.
- W4229072214 cites W2899114650 @default.
- W4229072214 cites W2900493058 @default.
- W4229072214 cites W2905035788 @default.
- W4229072214 cites W2907901432 @default.
- W4229072214 cites W2911336091 @default.
- W4229072214 cites W2916790876 @default.
- W4229072214 cites W2923186456 @default.
- W4229072214 cites W2932702265 @default.
- W4229072214 cites W2935369648 @default.
- W4229072214 cites W2938932754 @default.
- W4229072214 cites W2944170385 @default.
- W4229072214 cites W2945064325 @default.
- W4229072214 cites W2952499681 @default.
- W4229072214 cites W2953958215 @default.
- W4229072214 cites W2965121801 @default.
- W4229072214 cites W2970442091 @default.
- W4229072214 cites W2975460010 @default.
- W4229072214 cites W2980064551 @default.
- W4229072214 cites W2980216946 @default.
- W4229072214 cites W2982648824 @default.
- W4229072214 cites W2985562150 @default.
- W4229072214 cites W2986787922 @default.
- W4229072214 cites W2986793362 @default.
- W4229072214 cites W2986830112 @default.