Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229083845> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4229083845 endingPage "246" @default.
- W4229083845 startingPage "240" @default.
- W4229083845 abstract "Abstract: Aim: The purpose of this research study, is to develop and validate a reverse phase HPLC test method for detecting relevant impurities in Testosterone cypionate (TCY). Materials and Methods: The chromatographic system for separation of related impurities were achieved in Zorbax XDB-C8 (15 cm x 4.6 mm), 5 micron HPLC column utilising gradient elution technique. Water was selected as solvent-A and Acetonitrile was preferred as solvent-B for mobile phase. The method is gradient technique. Column heater was kept constant at 35°C; the rate of flow was 1.2 mL per min; volume of injection was 20 μL and 240 nm was set for detector wavelength. Results: The % recovery was in the range of 95.6% to 108.7% for all impurities. The result of correlation coefficient were higher than 0.98. Testosterone is the major degradants obtained from forced degradation study. Conclusion: The created method can be utilise in quality control testing on a regular basis for the analysis of Testosterone cypionate. Key words: Testosterone cypionate, Testosterone replacement therapy, Male hypogonadism, HPLC, Impurity profiling." @default.
- W4229083845 created "2022-05-08" @default.
- W4229083845 creator A5002513528 @default.
- W4229083845 creator A5018598097 @default.
- W4229083845 creator A5082903376 @default.
- W4229083845 date "2022-01-12" @default.
- W4229083845 modified "2023-09-25" @default.
- W4229083845 title "HPLC Method Development and Validation for the Quantification of Related Impurities in Testosterone Cypionate Active Pharmaceutical Ingredient" @default.
- W4229083845 doi "https://doi.org/10.5530/ijper.56.1.28" @default.
- W4229083845 hasPublicationYear "2022" @default.
- W4229083845 type Work @default.
- W4229083845 citedByCount "0" @default.
- W4229083845 crossrefType "journal-article" @default.
- W4229083845 hasAuthorship W4229083845A5002513528 @default.
- W4229083845 hasAuthorship W4229083845A5018598097 @default.
- W4229083845 hasAuthorship W4229083845A5082903376 @default.
- W4229083845 hasBestOaLocation W42290838451 @default.
- W4229083845 hasConcept C113196181 @default.
- W4229083845 hasConcept C126322002 @default.
- W4229083845 hasConcept C178790620 @default.
- W4229083845 hasConcept C179998833 @default.
- W4229083845 hasConcept C185592680 @default.
- W4229083845 hasConcept C2777463227 @default.
- W4229083845 hasConcept C2779279991 @default.
- W4229083845 hasConcept C2780471494 @default.
- W4229083845 hasConcept C3017686574 @default.
- W4229083845 hasConcept C43617362 @default.
- W4229083845 hasConcept C45904493 @default.
- W4229083845 hasConcept C71924100 @default.
- W4229083845 hasConcept C71987851 @default.
- W4229083845 hasConcept C73826308 @default.
- W4229083845 hasConcept C98274493 @default.
- W4229083845 hasConceptScore W4229083845C113196181 @default.
- W4229083845 hasConceptScore W4229083845C126322002 @default.
- W4229083845 hasConceptScore W4229083845C178790620 @default.
- W4229083845 hasConceptScore W4229083845C179998833 @default.
- W4229083845 hasConceptScore W4229083845C185592680 @default.
- W4229083845 hasConceptScore W4229083845C2777463227 @default.
- W4229083845 hasConceptScore W4229083845C2779279991 @default.
- W4229083845 hasConceptScore W4229083845C2780471494 @default.
- W4229083845 hasConceptScore W4229083845C3017686574 @default.
- W4229083845 hasConceptScore W4229083845C43617362 @default.
- W4229083845 hasConceptScore W4229083845C45904493 @default.
- W4229083845 hasConceptScore W4229083845C71924100 @default.
- W4229083845 hasConceptScore W4229083845C71987851 @default.
- W4229083845 hasConceptScore W4229083845C73826308 @default.
- W4229083845 hasConceptScore W4229083845C98274493 @default.
- W4229083845 hasIssue "1" @default.
- W4229083845 hasLocation W42290838451 @default.
- W4229083845 hasOpenAccess W4229083845 @default.
- W4229083845 hasPrimaryLocation W42290838451 @default.
- W4229083845 hasRelatedWork W1981648665 @default.
- W4229083845 hasRelatedWork W2015362886 @default.
- W4229083845 hasRelatedWork W2024867672 @default.
- W4229083845 hasRelatedWork W2043512602 @default.
- W4229083845 hasRelatedWork W2043863063 @default.
- W4229083845 hasRelatedWork W2052058093 @default.
- W4229083845 hasRelatedWork W2065074440 @default.
- W4229083845 hasRelatedWork W2119552130 @default.
- W4229083845 hasRelatedWork W2282687875 @default.
- W4229083845 hasRelatedWork W66516859 @default.
- W4229083845 hasVolume "56" @default.
- W4229083845 isParatext "false" @default.
- W4229083845 isRetracted "false" @default.
- W4229083845 workType "article" @default.