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- W4229336550 endingPage "705" @default.
- W4229336550 startingPage "691" @default.
- W4229336550 abstract "Low-grade inflammatory processes and related oxidative stress may have a key role in the pathogenesis of hypertension and hypertension-mediated organ damage. Innate immune cells, such as neutrophils, dendritic cells, monocytes/macrophages, as well as unconventional T lymphocytes like γδ T cells contribute to hypertension and may trigger vascular inflammation. Adaptive immunity has been demonstrated to participate in elevation of blood pressure and in vascular and kidney injury. In particular, effector T lymphocytes (Th1, Th2, and Th17) may play a relevant role in promoting hypertension and microvascular remodeling, whereas T-regulatory lymphocytes may have a protective role. Effector cytokines produced by these immune cells lead to increased oxidative stress, endothelial dysfunction and contribute to target organ damage in hypertension. A possible role of immune cell subpopulations in the development and regression of microvascular remodeling has also been proposed in humans with hypertension. The present review summarizes the key immune mechanisms that may participate in the pathophysiology of hypertension-mediated inflammation and vascular remodeling; advances in this field may provide the basis for novel therapeutics for hypertension." @default.
- W4229336550 created "2022-05-09" @default.
- W4229336550 creator A5003676876 @default.
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- W4229336550 creator A5027436936 @default.
- W4229336550 creator A5040329167 @default.
- W4229336550 creator A5046910928 @default.
- W4229336550 date "2022-04-01" @default.
- W4229336550 modified "2023-10-18" @default.
- W4229336550 title "Immune System and Microvascular Remodeling in Humans" @default.
- W4229336550 cites W1765750524 @default.
- W4229336550 cites W1832287084 @default.
- W4229336550 cites W1968908220 @default.
- W4229336550 cites W1975582897 @default.
- W4229336550 cites W1976444920 @default.
- W4229336550 cites W1990738873 @default.
- W4229336550 cites W1992229069 @default.
- W4229336550 cites W1995866677 @default.
- W4229336550 cites W2017663491 @default.
- W4229336550 cites W2020222860 @default.
- W4229336550 cites W2022765352 @default.
- W4229336550 cites W2035823839 @default.
- W4229336550 cites W2036695073 @default.
- W4229336550 cites W2051827607 @default.
- W4229336550 cites W2055247780 @default.
- W4229336550 cites W2056173975 @default.
- W4229336550 cites W2061595855 @default.
- W4229336550 cites W2063561249 @default.
- W4229336550 cites W2065645584 @default.
- W4229336550 cites W2073656482 @default.
- W4229336550 cites W2074123865 @default.
- W4229336550 cites W2096796741 @default.
- W4229336550 cites W2097792029 @default.
- W4229336550 cites W2113087028 @default.
- W4229336550 cites W2117185007 @default.
- W4229336550 cites W2122931571 @default.
- W4229336550 cites W2126025027 @default.
- W4229336550 cites W2126862979 @default.
- W4229336550 cites W2129777398 @default.
- W4229336550 cites W2133402519 @default.
- W4229336550 cites W2133493473 @default.
- W4229336550 cites W2137156703 @default.
- W4229336550 cites W2144896295 @default.
- W4229336550 cites W2145428033 @default.
- W4229336550 cites W2148770155 @default.
- W4229336550 cites W2152156058 @default.
- W4229336550 cites W2153626991 @default.
- W4229336550 cites W2155191545 @default.
- W4229336550 cites W2155504581 @default.
- W4229336550 cites W2167193994 @default.
- W4229336550 cites W2168671157 @default.
- W4229336550 cites W2181454853 @default.
- W4229336550 cites W2332421164 @default.
- W4229336550 cites W2337180881 @default.
- W4229336550 cites W2372703342 @default.
- W4229336550 cites W2396221546 @default.
- W4229336550 cites W2490120270 @default.
- W4229336550 cites W2522321878 @default.
- W4229336550 cites W2522449865 @default.
- W4229336550 cites W2524103344 @default.
- W4229336550 cites W2573920236 @default.
- W4229336550 cites W2589006352 @default.
- W4229336550 cites W2590072483 @default.
- W4229336550 cites W2594685645 @default.
- W4229336550 cites W2602400640 @default.
- W4229336550 cites W2604753011 @default.
- W4229336550 cites W2621371007 @default.
- W4229336550 cites W2744696790 @default.
- W4229336550 cites W2748400555 @default.
- W4229336550 cites W2762325358 @default.
- W4229336550 cites W2765521509 @default.
- W4229336550 cites W2769170966 @default.
- W4229336550 cites W2801628865 @default.
- W4229336550 cites W2803875087 @default.
- W4229336550 cites W2810785966 @default.
- W4229336550 cites W2883266158 @default.
- W4229336550 cites W2888984898 @default.
- W4229336550 cites W2899545787 @default.
- W4229336550 cites W2909928304 @default.
- W4229336550 cites W2947815614 @default.
- W4229336550 cites W2948485373 @default.
- W4229336550 cites W2948863714 @default.
- W4229336550 cites W2961737246 @default.
- W4229336550 cites W2969472398 @default.
- W4229336550 cites W2970531235 @default.
- W4229336550 cites W2975445774 @default.
- W4229336550 cites W2986700515 @default.
- W4229336550 cites W2999741749 @default.
- W4229336550 cites W3000036487 @default.
- W4229336550 cites W3000252808 @default.
- W4229336550 cites W3001966161 @default.
- W4229336550 cites W3002577956 @default.
- W4229336550 cites W3003109697 @default.
- W4229336550 cites W3004147923 @default.
- W4229336550 cites W3005427274 @default.
- W4229336550 cites W3005754632 @default.
- W4229336550 cites W3007173220 @default.