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• W4229370271 abstract "Background:The burden of neurological disorders is large and altered by the HIV epidemic.&#x0D; Objectives: We describe the pattern of neurological disorders and their association with HIV infection in adult patients attending a consultant hospital in Northern Tanzania.&#x0D; Methods: In this prospective cross-sectional study, we collected data on adult neurological referrals over a 6-year period between 2007-13. The odds of HIV infection, across neurological categories adjusted for age and sex, was calculated.&#x0D; Results: Of 2037 participants, 54.8% were male and 45.2% were female. The median age of participants was 43 years. The results for HIV screening were available for 992/2037 (48.7%) patients, of whom 306 (30.8%) were seropositive. The most frequent neurological disorders were cerebrovascular disease (19.9%), paraplegia (13.6%), and peripheral neuropathies (8%). Taken together CNS infection accounted for 278/2037 (13.6%). The adjusted odds (aOR) of HIV infection was highest amongst infections; brain abscesses (aOR 107, 95% CI 35.1-470.4) and meningitis/encephalitis (aOR 40.1, 95% CI 13.6-172.9), but also raised in cerebrovascular disease, paraplegia, peripheral neuropathies, cranial nerve palsies, seizures, cerebllar disorders, movement disorders, motor neuron disease andheadache.&#x0D; Conclusion: The main pattern of neurological disorders in Northern Tanzania is presented. The odds of HIV infection was highest in CNS infections and in a wide range of non-communicable neurological disorders.&#x0D; Keywords: Tanzania; neurological; disorder; neurological disease; hospital; HIV" @default.
• W4229370271 created "2022-05-10" @default.
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• W4229370271 date "2022-04-29" @default.
• W4229370271 modified "2023-10-16" @default.
• W4229370271 title "Neurological disorders in Northern Tanzania: A 6-year prospective hospital-based case series" @default.
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• W4229370271 doi "https://doi.org/10.4314/ahs.v22i1.34" @default.
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