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- W4229372160 abstract "The lungs are constantly exposed to environmental and infectious agents such as dust, viruses, fungi, and bacteria that invade the lungs upon breathing. The lungs are equipped with an immune defense mechanism that involves a wide variety of immunological cells to eliminate these agents. Various types of dendritic cells (DCs) and macrophages (MACs) function as professional antigen-presenting cells (APCs) that engulf pathogens through endocytosis or phagocytosis and degrade proteins derived from them into peptide fragments. During this process, DCs and MACs present the peptides on their major histocompatibility complex class I (MHC-I) or MHC-II protein complex to naïve CD8+ or CD4+ T cells, respectively. In addition to these cells, recent evidence supports that antigen-specific effector and memory T cells are activated by other lung cells such as endothelial cells, epithelial cells, and monocytes through antigen presentation. In this review, we summarize the molecular mechanisms of antigen presentation by APCs in the lungs and their contribution to immune response." @default.
- W4229372160 created "2022-05-10" @default.
- W4229372160 creator A5035590411 @default.
- W4229372160 creator A5062825404 @default.
- W4229372160 creator A5078731551 @default.
- W4229372160 date "2022-05-09" @default.
- W4229372160 modified "2023-10-11" @default.
- W4229372160 title "Antigen Presentation in the Lung" @default.
- W4229372160 cites W1502147118 @default.
- W4229372160 cites W1525176639 @default.
- W4229372160 cites W1539936851 @default.
- W4229372160 cites W1544769291 @default.
- W4229372160 cites W1584203472 @default.
- W4229372160 cites W1631977896 @default.
- W4229372160 cites W1661544713 @default.
- W4229372160 cites W1716725129 @default.
- W4229372160 cites W1720634740 @default.
- W4229372160 cites W1742769645 @default.
- W4229372160 cites W1752957211 @default.
- W4229372160 cites W1779160407 @default.
- W4229372160 cites W1860664166 @default.
- W4229372160 cites W1877177768 @default.
- W4229372160 cites W1920177081 @default.
- W4229372160 cites W1929002362 @default.
- W4229372160 cites W1948478725 @default.
- W4229372160 cites W1950729478 @default.
- W4229372160 cites W1963584953 @default.
- W4229372160 cites W1964747179 @default.
- W4229372160 cites W1967879964 @default.
- W4229372160 cites W1970654655 @default.
- W4229372160 cites W1971666638 @default.
- W4229372160 cites W1973139453 @default.
- W4229372160 cites W1973362572 @default.
- W4229372160 cites W1973615265 @default.
- W4229372160 cites W1973717482 @default.
- W4229372160 cites W1973753526 @default.
- W4229372160 cites W1975155714 @default.
- W4229372160 cites W1975910541 @default.
- W4229372160 cites W1977142289 @default.
- W4229372160 cites W1981858801 @default.
- W4229372160 cites W1987481383 @default.
- W4229372160 cites W1993489331 @default.
- W4229372160 cites W1993547722 @default.
- W4229372160 cites W1994048581 @default.
- W4229372160 cites W1998933515 @default.
- W4229372160 cites W1998952750 @default.
- W4229372160 cites W2002051393 @default.
- W4229372160 cites W2006493141 @default.
- W4229372160 cites W2007056945 @default.
- W4229372160 cites W2008794823 @default.
- W4229372160 cites W2011270644 @default.
- W4229372160 cites W2017127553 @default.
- W4229372160 cites W2020746301 @default.
- W4229372160 cites W2021623714 @default.
- W4229372160 cites W2022281511 @default.
- W4229372160 cites W2022751366 @default.
- W4229372160 cites W2023666964 @default.
- W4229372160 cites W2027613710 @default.
- W4229372160 cites W2032528769 @default.
- W4229372160 cites W2036564362 @default.
- W4229372160 cites W2038068026 @default.
- W4229372160 cites W2038141921 @default.
- W4229372160 cites W2040739057 @default.
- W4229372160 cites W2041894425 @default.
- W4229372160 cites W2043745393 @default.
- W4229372160 cites W2043982114 @default.
- W4229372160 cites W2045121415 @default.
- W4229372160 cites W2046505430 @default.
- W4229372160 cites W2046700010 @default.
- W4229372160 cites W2046781420 @default.
- W4229372160 cites W2047585875 @default.
- W4229372160 cites W2048403514 @default.
- W4229372160 cites W2049909747 @default.
- W4229372160 cites W2050708499 @default.
- W4229372160 cites W2052736790 @default.
- W4229372160 cites W2055039738 @default.
- W4229372160 cites W2055480930 @default.
- W4229372160 cites W2056628849 @default.
- W4229372160 cites W2061538006 @default.
- W4229372160 cites W2066177626 @default.
- W4229372160 cites W2068051174 @default.
- W4229372160 cites W2068853695 @default.
- W4229372160 cites W2079439306 @default.
- W4229372160 cites W2083106544 @default.
- W4229372160 cites W2083872083 @default.
- W4229372160 cites W2085099489 @default.
- W4229372160 cites W2085695854 @default.
- W4229372160 cites W2093168274 @default.
- W4229372160 cites W2096511670 @default.
- W4229372160 cites W2098754939 @default.
- W4229372160 cites W2098861154 @default.
- W4229372160 cites W2100646399 @default.
- W4229372160 cites W2102033291 @default.
- W4229372160 cites W2103153413 @default.
- W4229372160 cites W2104058942 @default.
- W4229372160 cites W2105329191 @default.
- W4229372160 cites W2105818762 @default.
- W4229372160 cites W2108449579 @default.
- W4229372160 cites W2108765339 @default.
- W4229372160 cites W2109491705 @default.