FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229376105> ?p ?o ?g. }

• W4229376105 abstract "The utility of heated intraperitoneal chemotherapy (HIPEC) in the management of epithelial ovarian cancer (EOC) has been assessed in several randomised clinical trials and meta-analyses, and it is still a subject of controversy. Therefore, we performed an umbrella review of existing meta-analyses to summarise the outcomes of HIPEC and cytoreductive surgery (CRS) association in ovarian cancer.We examined the MEDLINE, Cochrane Library, Scopus, Prospero, Web of Science and Science Direct from inception to May 30, 2020, for meta-analyses of randomised controlled trials and observational studies. Analyses of overall survival, disease free survival and progression survival were performed separately for primary and recurrent ovarian cancers.We identified 6 meta-analyses investigating the association of HIPEC with CRS in the management of ovarian cancer. Three year overall survival was significantly improved by the association of CRS and HIPEC for primary (HR: 0.66, 95%CI:0.56-0.78) and recurrent ovarian cancers (HR:0.50, 95%CI:0.38-0.64). This benefit was also demonstrated on disease-free survival for primary (HR: 0.54, 95%CI:0.48-0.61) and recurrent ovarian cancer (HR: 0.60, 95%CI:0.46-0.78). The pooled hazard ratios confirmed the advantage of HIPEC and CRS association with respect to CRS alone on progression free survival for primary and recurrent ovarian cancer respectively with HR: 0.50, 95%CI: 0.43-0.58 and HR: 0.59, 95%CI: 0.41-0.85.While waiting for the results of the current prospective studies, the present umbrella study suggests that HIPEC performed at the end of CRS may be a complementary effective asset for ovarian cancer patient management." @default.
• W4229376105 created "2022-05-10" @default.
• W4229376105 creator A5010882316 @default.
• W4229376105 creator A5031036666 @default.
• W4229376105 creator A5053758396 @default.
• W4229376105 creator A5055057446 @default.
• W4229376105 creator A5066405861 @default.
• W4229376105 creator A5067029264 @default.
• W4229376105 creator A5073787373 @default.
• W4229376105 creator A5083458304 @default.
• W4229376105 creator A5088879599 @default.
• W4229376105 date "2022-05-09" @default.
• W4229376105 modified "2023-10-14" @default.
• W4229376105 title "Hyperthermic Intraperitoneal Chemotherapy and Cytoreductive Surgery in Ovarian Cancer: An Umbrella Review of Meta-Analyses" @default.
• W4229376105 cites W1563590460 @default.
• W4229376105 cites W1695269563 @default.
• W4229376105 cites W1927140829 @default.
• W4229376105 cites W1964023152 @default.
• W4229376105 cites W1970581049 @default.
• W4229376105 cites W1993080821 @default.
• W4229376105 cites W2000124372 @default.
• W4229376105 cites W2003178123 @default.
• W4229376105 cites W2003563462 @default.
• W4229376105 cites W2009097203 @default.
• W4229376105 cites W2029957790 @default.
• W4229376105 cites W2038759480 @default.
• W4229376105 cites W2042633087 @default.
• W4229376105 cites W2063098268 @default.
• W4229376105 cites W2106767659 @default.
• W4229376105 cites W2123458589 @default.
• W4229376105 cites W2260361758 @default.
• W4229376105 cites W2268410895 @default.
• W4229376105 cites W2303228658 @default.
• W4229376105 cites W2316400036 @default.
• W4229376105 cites W2410589321 @default.
• W4229376105 cites W2438866487 @default.
• W4229376105 cites W2486522473 @default.
• W4229376105 cites W2510895703 @default.
• W4229376105 cites W2557603774 @default.
• W4229376105 cites W2579152176 @default.
• W4229376105 cites W2594404528 @default.
• W4229376105 cites W2737281516 @default.
• W4229376105 cites W2756578555 @default.
• W4229376105 cites W2784597821 @default.
• W4229376105 cites W2898363357 @default.
• W4229376105 cites W2910145550 @default.
• W4229376105 cites W2935067372 @default.
• W4229376105 cites W2937594202 @default.
• W4229376105 cites W2943415606 @default.
• W4229376105 cites W2945319365 @default.
• W4229376105 cites W2947330258 @default.
• W4229376105 cites W2994639315 @default.
• W4229376105 cites W3010197652 @default.
• W4229376105 cites W3015445624 @default.
• W4229376105 cites W3019754238 @default.
• W4229376105 cites W3022180314 @default.
• W4229376105 cites W3031621470 @default.
• W4229376105 cites W3048333485 @default.
• W4229376105 cites W3080829449 @default.
• W4229376105 cites W3082386314 @default.
• W4229376105 cites W3133494860 @default.
• W4229376105 cites W3143358307 @default.
• W4229376105 cites W3201437718 @default.
• W4229376105 cites W4234458906 @default.
• W4229376105 cites W4240406078 @default.
• W4229376105 cites W600840809 @default.
• W4229376105 doi "https://doi.org/10.3389/fonc.2022.809773" @default.
• W4229376105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35615149" @default.
• W4229376105 hasPublicationYear "2022" @default.
• W4229376105 type Work @default.
• W4229376105 citedByCount "7" @default.
• W4229376105 countsByYear W42293761052022 @default.
• W4229376105 countsByYear W42293761052023 @default.
• W4229376105 crossrefType "journal-article" @default.
• W4229376105 hasAuthorship W4229376105A5010882316 @default.
• W4229376105 hasAuthorship W4229376105A5031036666 @default.
• W4229376105 hasAuthorship W4229376105A5053758396 @default.
• W4229376105 hasAuthorship W4229376105A5055057446 @default.
• W4229376105 hasAuthorship W4229376105A5066405861 @default.
• W4229376105 hasAuthorship W4229376105A5067029264 @default.
• W4229376105 hasAuthorship W4229376105A5073787373 @default.
• W4229376105 hasAuthorship W4229376105A5083458304 @default.
• W4229376105 hasAuthorship W4229376105A5088879599 @default.
• W4229376105 hasBestOaLocation W42293761051 @default.
• W4229376105 hasConcept C121608353 @default.
• W4229376105 hasConcept C126322002 @default.
• W4229376105 hasConcept C143998085 @default.
• W4229376105 hasConcept C168563851 @default.
• W4229376105 hasConcept C207103383 @default.
• W4229376105 hasConcept C2776478404 @default.
• W4229376105 hasConcept C2776694085 @default.
• W4229376105 hasConcept C2779458272 @default.
• W4229376105 hasConcept C2780427987 @default.
• W4229376105 hasConcept C2994223192 @default.
• W4229376105 hasConcept C44249647 @default.
• W4229376105 hasConcept C71924100 @default.
• W4229376105 hasConcept C95190672 @default.
• W4229376105 hasConceptScore W4229376105C121608353 @default.
• W4229376105 hasConceptScore W4229376105C126322002 @default.
• W4229376105 hasConceptScore W4229376105C143998085 @default.

• next