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- W4229377289 abstract "Since a new contagion novel coronavirus (SARS-CoV2) emerged in Wuhan, China, it has been nearly two years. There are still so many unknowns surrounding SARS-CoV2 which causes deadly pneumonia and multiorgan involvement. Here we introduce a patient with severe coronavirus disease 2019 (COVID-19) who presented with respiratory symptoms and muscle pain. After an immediate blood investigation we observed high creatine kinase and myoglobin in the blood sample. With myoglobinuria in spot urine and decreased renal function rhabdomyolysis diagnosis was made. We investigated all causes that induce rhabdomyolysis. After full medical history and several analyses, the favipiravir induced rhabdomyolysis diagnosis was made. A 51-year-old male patient presented to our clinic with shortness of breath, muscle pain, fatigue, fevers and cough. A pulmonary examination revealed crackles in both lung bases. Otherwise, his physical examination was unremarkable. From the day of admission he was supported by ventilator and high oxygen. Subsequently his positive end expiratory pressure and oxygen requirements increased. Although we did not rule out a possible direct SARS-CoV2 injury on muscle, it9s unlikely cause. Because, despite his worsening respiratory condition right after the admission, his muscle enzyme levels decreased eventually with discontinuation of favipiravir medication that he had been taking for four days with treatment protocol of 1600-600-600-600mg. He had no other medical condition and was on no medications that could cause rhabdomyolysis. This is one of the several reported favipiravir induced rhabdomyolysis cases. More studies should held in this group of patients to be aware of this serious complication." @default.
- W4229377289 created "2022-05-10" @default.
- W4229377289 creator A5011197457 @default.
- W4229377289 date "2022-03-10" @default.
- W4229377289 modified "2023-09-27" @default.
- W4229377289 title "Favipiravir induced rhabdomyolysis in patient with severe COVID-19 pneumonia" @default.
- W4229377289 doi "https://doi.org/10.1183/23120541.lsc-2022.99" @default.
- W4229377289 hasPublicationYear "2022" @default.
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