Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229440143> ?p ?o ?g. }
- W4229440143 abstract "Abstract This study aims to evaluate the feasibility and cardio-protective effects of biocompatible silicon-built restraint device (ASD) in the rat’s heart failure (HF) model. The performance and compliance characteristics of the ASD device were assessed in vitro by adopting a pneumatic drive and ball burst test. Sprague-Dawley (SD) rats were divided into four groups ( n = 6); control, HF, HF + CSD, and HF + ASD groups, respectively. Heart failure was developed by left anterior descending (LAD) coronary artery ligation in all groups except the control group. The ASD and CSD devices were implanted in the heart of HF + ASD and HF + CSD groups, respectively. The ASD’s functional and expansion ability was found to be safe and suitable for attenuating ventricular remodeling. ASD-treated rats showed normal heart rhythm, demonstrated by smooth -ST and asymmetrical T-wave. At the same time, hemodynamic parameters of the HF + ASD group improved systolic and diastolic functions, reducing ventricular wall stress, which indicated reverse remodeling. The BNP values were reduced in the HF + ASD group, which confirmed ASD feasibility and reversed remodeling at a molecular level. Furthermore, the HF + ASD group with no fibrosis suggests that ASD has significant curative effects on the heart muscles. In conclusion, ASD was found to be a promising restraint therapy than the previously standard restraint therapies." @default.
- W4229440143 created "2022-05-11" @default.
- W4229440143 creator A5001128881 @default.
- W4229440143 creator A5015866331 @default.
- W4229440143 creator A5024061152 @default.
- W4229440143 creator A5031035876 @default.
- W4229440143 creator A5054611808 @default.
- W4229440143 creator A5059618475 @default.
- W4229440143 creator A5068510041 @default.
- W4229440143 creator A5071660408 @default.
- W4229440143 creator A5079679275 @default.
- W4229440143 creator A5084823078 @default.
- W4229440143 date "2022-05-01" @default.
- W4229440143 modified "2023-09-26" @default.
- W4229440143 title "Cardioprotective effect of silicon-built restraint device (ASD), for left ventricular remodeling in rat heart failure model" @default.
- W4229440143 cites W121724811 @default.
- W4229440143 cites W1563515539 @default.
- W4229440143 cites W1946625793 @default.
- W4229440143 cites W1964765733 @default.
- W4229440143 cites W1965323627 @default.
- W4229440143 cites W1966182783 @default.
- W4229440143 cites W1973253878 @default.
- W4229440143 cites W1974988360 @default.
- W4229440143 cites W1982372873 @default.
- W4229440143 cites W2003687987 @default.
- W4229440143 cites W2007190145 @default.
- W4229440143 cites W2009114046 @default.
- W4229440143 cites W2012524269 @default.
- W4229440143 cites W2016028402 @default.
- W4229440143 cites W2018450541 @default.
- W4229440143 cites W2034970437 @default.
- W4229440143 cites W2038540078 @default.
- W4229440143 cites W2039573320 @default.
- W4229440143 cites W2050784777 @default.
- W4229440143 cites W2051190228 @default.
- W4229440143 cites W2054018312 @default.
- W4229440143 cites W2055046639 @default.
- W4229440143 cites W2067450773 @default.
- W4229440143 cites W2087615653 @default.
- W4229440143 cites W2092575722 @default.
- W4229440143 cites W2094692557 @default.
- W4229440143 cites W2108790161 @default.
- W4229440143 cites W2123950519 @default.
- W4229440143 cites W2134898232 @default.
- W4229440143 cites W2139003809 @default.
- W4229440143 cites W2151986333 @default.
- W4229440143 cites W2169886650 @default.
- W4229440143 cites W2244280198 @default.
- W4229440143 cites W2299099463 @default.
- W4229440143 cites W2408652742 @default.
- W4229440143 cites W2408876038 @default.
- W4229440143 cites W2502196638 @default.
- W4229440143 cites W2572814675 @default.
- W4229440143 cites W2593729193 @default.
- W4229440143 cites W2753694966 @default.
- W4229440143 cites W2782607219 @default.
- W4229440143 cites W2792743255 @default.
- W4229440143 cites W2802953319 @default.
- W4229440143 cites W2935430241 @default.
- W4229440143 cites W2954861211 @default.
- W4229440143 cites W3016476244 @default.
- W4229440143 cites W3080636827 @default.
- W4229440143 cites W4255009698 @default.
- W4229440143 cites W4293084779 @default.
- W4229440143 cites W601053047 @default.
- W4229440143 doi "https://doi.org/10.1007/s10856-022-06663-6" @default.
- W4229440143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35536369" @default.
- W4229440143 hasPublicationYear "2022" @default.
- W4229440143 type Work @default.
- W4229440143 citedByCount "1" @default.
- W4229440143 countsByYear W42294401432023 @default.
- W4229440143 crossrefType "journal-article" @default.
- W4229440143 hasAuthorship W4229440143A5001128881 @default.
- W4229440143 hasAuthorship W4229440143A5015866331 @default.
- W4229440143 hasAuthorship W4229440143A5024061152 @default.
- W4229440143 hasAuthorship W4229440143A5031035876 @default.
- W4229440143 hasAuthorship W4229440143A5054611808 @default.
- W4229440143 hasAuthorship W4229440143A5059618475 @default.
- W4229440143 hasAuthorship W4229440143A5068510041 @default.
- W4229440143 hasAuthorship W4229440143A5071660408 @default.
- W4229440143 hasAuthorship W4229440143A5079679275 @default.
- W4229440143 hasAuthorship W4229440143A5084823078 @default.
- W4229440143 hasBestOaLocation W42294401431 @default.
- W4229440143 hasConcept C126322002 @default.
- W4229440143 hasConcept C164705383 @default.
- W4229440143 hasConcept C178853913 @default.
- W4229440143 hasConcept C179437574 @default.
- W4229440143 hasConcept C2778198053 @default.
- W4229440143 hasConcept C2779537366 @default.
- W4229440143 hasConcept C57900726 @default.
- W4229440143 hasConcept C71924100 @default.
- W4229440143 hasConcept C84393581 @default.
- W4229440143 hasConceptScore W4229440143C126322002 @default.
- W4229440143 hasConceptScore W4229440143C164705383 @default.
- W4229440143 hasConceptScore W4229440143C178853913 @default.
- W4229440143 hasConceptScore W4229440143C179437574 @default.
- W4229440143 hasConceptScore W4229440143C2778198053 @default.
- W4229440143 hasConceptScore W4229440143C2779537366 @default.
- W4229440143 hasConceptScore W4229440143C57900726 @default.
- W4229440143 hasConceptScore W4229440143C71924100 @default.