Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229441379> ?p ?o ?g. }
- W4229441379 endingPage "1021" @default.
- W4229441379 startingPage "1021" @default.
- W4229441379 abstract "The rapid rise in the health burden associated with chronic wounds is of great concern to policymakers, academia, and industry. This could be attributed to the devastating implications of this condition, and specifically, chronic wounds which have been linked to invasive microbial infections affecting patients’ quality of life. Unfortunately, antibiotics are not always helpful due to their poor penetration of bacterial biofilms and the emergence of antimicrobial resistance. Hence, there is an urgent need to explore antibiotics-free compounds/formulations with proven or potential antimicrobial, anti-inflammatory, antioxidant, and wound healing efficacy. The mechanism of antibiotics-free compounds is thought to include the disruption of the bacteria cell structure, preventing cell division, membrane porins, motility, and the formation of a biofilm. Furthermore, some of these compounds foster tissue regeneration by modulating growth factor expression. In this review article, the focus is placed on a number of non-antibiotic compounds possessing some of the aforementioned pharmacological and physiological activities. Specific interest is given to Aloevera, curcumin, cinnamaldehyde, polyhexanide, retinoids, ascorbate, tocochromanols, and chitosan. These compounds (when alone or in formulation with other biologically active molecules) could be a dependable alternative in the management or prevention of chronic wounds." @default.
- W4229441379 created "2022-05-11" @default.
- W4229441379 creator A5034893734 @default.
- W4229441379 creator A5054969952 @default.
- W4229441379 creator A5062333301 @default.
- W4229441379 date "2022-05-09" @default.
- W4229441379 modified "2023-10-02" @default.
- W4229441379 title "Antibiotics-Free Compounds for Chronic Wound Healing" @default.
- W4229441379 cites W102606094 @default.
- W4229441379 cites W1506756493 @default.
- W4229441379 cites W1514488234 @default.
- W4229441379 cites W1592608805 @default.
- W4229441379 cites W1608217646 @default.
- W4229441379 cites W1658177200 @default.
- W4229441379 cites W1809035786 @default.
- W4229441379 cites W1941294128 @default.
- W4229441379 cites W1964867222 @default.
- W4229441379 cites W1965552413 @default.
- W4229441379 cites W1968712423 @default.
- W4229441379 cites W1969257164 @default.
- W4229441379 cites W1972315718 @default.
- W4229441379 cites W1976942216 @default.
- W4229441379 cites W1978734460 @default.
- W4229441379 cites W1980511079 @default.
- W4229441379 cites W1980923037 @default.
- W4229441379 cites W1981221017 @default.
- W4229441379 cites W1981397830 @default.
- W4229441379 cites W1982595019 @default.
- W4229441379 cites W1984019274 @default.
- W4229441379 cites W1986560085 @default.
- W4229441379 cites W198703512 @default.
- W4229441379 cites W1987669529 @default.
- W4229441379 cites W1988292100 @default.
- W4229441379 cites W1988698239 @default.
- W4229441379 cites W1988958161 @default.
- W4229441379 cites W1989892378 @default.
- W4229441379 cites W1993600060 @default.
- W4229441379 cites W1994973707 @default.
- W4229441379 cites W1999266884 @default.
- W4229441379 cites W1999312756 @default.
- W4229441379 cites W2005108788 @default.
- W4229441379 cites W2007547328 @default.
- W4229441379 cites W2009670660 @default.
- W4229441379 cites W2011844535 @default.
- W4229441379 cites W2013617772 @default.
- W4229441379 cites W2017557214 @default.
- W4229441379 cites W2017789103 @default.
- W4229441379 cites W2019736888 @default.
- W4229441379 cites W2022885537 @default.
- W4229441379 cites W2023424717 @default.
- W4229441379 cites W2025363557 @default.
- W4229441379 cites W2026748467 @default.
- W4229441379 cites W2028629615 @default.
- W4229441379 cites W2033664879 @default.
- W4229441379 cites W2035958466 @default.
- W4229441379 cites W2037096236 @default.
- W4229441379 cites W2038077765 @default.
- W4229441379 cites W2041764058 @default.
- W4229441379 cites W2044105617 @default.
- W4229441379 cites W2046429159 @default.
- W4229441379 cites W2047076693 @default.
- W4229441379 cites W2047705770 @default.
- W4229441379 cites W2047742437 @default.
- W4229441379 cites W2048189573 @default.
- W4229441379 cites W2048620231 @default.
- W4229441379 cites W2050248964 @default.
- W4229441379 cites W2052084403 @default.
- W4229441379 cites W2052253693 @default.
- W4229441379 cites W2058235840 @default.
- W4229441379 cites W2061215349 @default.
- W4229441379 cites W2062737756 @default.
- W4229441379 cites W2063368340 @default.
- W4229441379 cites W2069356522 @default.
- W4229441379 cites W2070291030 @default.
- W4229441379 cites W2072175441 @default.
- W4229441379 cites W2073798776 @default.
- W4229441379 cites W2076491038 @default.
- W4229441379 cites W2077292033 @default.
- W4229441379 cites W2078429093 @default.
- W4229441379 cites W2081261734 @default.
- W4229441379 cites W2081764095 @default.
- W4229441379 cites W2083245140 @default.
- W4229441379 cites W2084896100 @default.
- W4229441379 cites W2086952722 @default.
- W4229441379 cites W2087016283 @default.
- W4229441379 cites W2087870296 @default.
- W4229441379 cites W2090649079 @default.
- W4229441379 cites W2091446928 @default.
- W4229441379 cites W2091651320 @default.
- W4229441379 cites W2092987378 @default.
- W4229441379 cites W2093739710 @default.
- W4229441379 cites W2094863669 @default.
- W4229441379 cites W2095169355 @default.
- W4229441379 cites W2096685256 @default.
- W4229441379 cites W2101244137 @default.
- W4229441379 cites W2104182395 @default.
- W4229441379 cites W2108487714 @default.
- W4229441379 cites W2108504295 @default.