Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229523430> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W4229523430 abstract "Abstract By May 2021, over 160 million SARS-CoV-2 diagnoses have been reported worldwide. Yet, the true number of infections is unknown and believed to exceed the reported numbers by several fold. National testing policies, in particular, can strongly affect the proportion of undetected cases. Here, we propose a novel method (GInPipe) that reconstructs SARS-CoV-2 incidence profiles within minutes, solely from publicly available, time-stamped viral genomes. We validated GInPipe against in silico generated outbreak data and elaborate phylodynamic analyses. We apply the method to reconstruct incidence histories from sequence data for Denmark, Scotland, Switzerland, and Victoria (Australia). GInPipe reconstructs the different pandemic waves robustly and remarkably accurate. We demonstrate how the method can be used to investigate the effects of changing testing policies on the probability to diagnose and report infected individuals. Specifically, we find that under-reporting was highest in mid 2020 in parts of Europe, coinciding with changes towards more liberal testing policies at times of low testing capacities. Due to the increased use of real-time sequencing, it is envisaged that GInPipe can complement established surveillance tools to monitor the SARS-CoV-2 pandemic. We anticipate that the method is particularly useful in settings where diagnostic and reporting infrastructures are insufficient. In ‘post-pandemic’ times, when diagnostic efforts are decreased, GInPipe may facilitate the detection of hidden infection dynamics." @default.
- W4229523430 created "2022-05-11" @default.
- W4229523430 creator A5014129810 @default.
- W4229523430 creator A5014242518 @default.
- W4229523430 creator A5025504717 @default.
- W4229523430 creator A5065428786 @default.
- W4229523430 creator A5066288679 @default.
- W4229523430 creator A5089767325 @default.
- W4229523430 date "2021-05-27" @default.
- W4229523430 modified "2023-10-17" @default.
- W4229523430 title "Rapid incidence estimation from SARS-CoV-2 genomes reveals decreased case detection in Europe during summer 2020" @default.
- W4229523430 doi "https://doi.org/10.21203/rs.3.rs-558667/v1" @default.
- W4229523430 hasPublicationYear "2021" @default.
- W4229523430 type Work @default.
- W4229523430 citedByCount "0" @default.
- W4229523430 crossrefType "posted-content" @default.
- W4229523430 hasAuthorship W4229523430A5014129810 @default.
- W4229523430 hasAuthorship W4229523430A5014242518 @default.
- W4229523430 hasAuthorship W4229523430A5025504717 @default.
- W4229523430 hasAuthorship W4229523430A5065428786 @default.
- W4229523430 hasAuthorship W4229523430A5066288679 @default.
- W4229523430 hasAuthorship W4229523430A5089767325 @default.
- W4229523430 hasBestOaLocation W42295234301 @default.
- W4229523430 hasConcept C116675565 @default.
- W4229523430 hasConcept C120665830 @default.
- W4229523430 hasConcept C121332964 @default.
- W4229523430 hasConcept C142724271 @default.
- W4229523430 hasConcept C144024400 @default.
- W4229523430 hasConcept C149923435 @default.
- W4229523430 hasConcept C159047783 @default.
- W4229523430 hasConcept C162324750 @default.
- W4229523430 hasConcept C187736073 @default.
- W4229523430 hasConcept C205649164 @default.
- W4229523430 hasConcept C2779134260 @default.
- W4229523430 hasConcept C3006700255 @default.
- W4229523430 hasConcept C3007834351 @default.
- W4229523430 hasConcept C3008058167 @default.
- W4229523430 hasConcept C41008148 @default.
- W4229523430 hasConcept C524204448 @default.
- W4229523430 hasConcept C61511704 @default.
- W4229523430 hasConcept C71924100 @default.
- W4229523430 hasConcept C86803240 @default.
- W4229523430 hasConcept C89623803 @default.
- W4229523430 hasConcept C96250715 @default.
- W4229523430 hasConceptScore W4229523430C116675565 @default.
- W4229523430 hasConceptScore W4229523430C120665830 @default.
- W4229523430 hasConceptScore W4229523430C121332964 @default.
- W4229523430 hasConceptScore W4229523430C142724271 @default.
- W4229523430 hasConceptScore W4229523430C144024400 @default.
- W4229523430 hasConceptScore W4229523430C149923435 @default.
- W4229523430 hasConceptScore W4229523430C159047783 @default.
- W4229523430 hasConceptScore W4229523430C162324750 @default.
- W4229523430 hasConceptScore W4229523430C187736073 @default.
- W4229523430 hasConceptScore W4229523430C205649164 @default.
- W4229523430 hasConceptScore W4229523430C2779134260 @default.
- W4229523430 hasConceptScore W4229523430C3006700255 @default.
- W4229523430 hasConceptScore W4229523430C3007834351 @default.
- W4229523430 hasConceptScore W4229523430C3008058167 @default.
- W4229523430 hasConceptScore W4229523430C41008148 @default.
- W4229523430 hasConceptScore W4229523430C524204448 @default.
- W4229523430 hasConceptScore W4229523430C61511704 @default.
- W4229523430 hasConceptScore W4229523430C71924100 @default.
- W4229523430 hasConceptScore W4229523430C86803240 @default.
- W4229523430 hasConceptScore W4229523430C89623803 @default.
- W4229523430 hasConceptScore W4229523430C96250715 @default.
- W4229523430 hasLocation W42295234301 @default.
- W4229523430 hasLocation W42295234302 @default.
- W4229523430 hasLocation W42295234303 @default.
- W4229523430 hasLocation W42295234304 @default.
- W4229523430 hasOpenAccess W4229523430 @default.
- W4229523430 hasPrimaryLocation W42295234301 @default.
- W4229523430 hasRelatedWork W3017171836 @default.
- W4229523430 hasRelatedWork W3025176011 @default.
- W4229523430 hasRelatedWork W3027835066 @default.
- W4229523430 hasRelatedWork W3032320397 @default.
- W4229523430 hasRelatedWork W3033635008 @default.
- W4229523430 hasRelatedWork W3152606407 @default.
- W4229523430 hasRelatedWork W4280491013 @default.
- W4229523430 hasRelatedWork W4308017287 @default.
- W4229523430 hasRelatedWork W3107152225 @default.
- W4229523430 hasRelatedWork W3183300108 @default.
- W4229523430 isParatext "false" @default.
- W4229523430 isRetracted "false" @default.
- W4229523430 workType "article" @default.