Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229546755> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4229546755 abstract "Abstract Background: The existing studies on the association between polymorphisms of Matrix metalloproteinase-1 (MMP-1) (-1607 1G/2G) (rs1799750) polymorphism and the risk of knee osteoarthritis (OA, a complex multifactorial disease and a major degenerative form of arthritis) in different populations have yielded conflicting findings. Method: Literature search was performed in PubMed, Cochrane Library, Web of science, Google Scholar (From January 1990 to June 2019), and assessing this association by calculating odds ratios with 95% confidence intervals. Subgroup analyses stratified by ethnicity were also conducted. Statistical heterogeneity was quantitatively evaluated by X 2 test with the significance set P<0.10 or I 2 >50%. Result: Five case-control based studies (924 cases and 928 controls) were included. The results suggested that the MMP-1 (-1607 1G/2G) (rs1799750) gene polymorphisms were not associated with knee OA risk in all genetic models (Allele model OR =1.22, 95% CI: 0.72-1.76, p=0.615, Recessive model OR = 1.12, 95% CI: 0.70-2.15, p=0.486, and Dominant model OR = 1.14, 95%CI: 0.64-2.04, p=0.659, Figure 3-5) Conclusions: There is no association between the polymorphism of MMP-1 (-1607 1G/2G) (rs1799750) polymorphism with the risk of knee osteoarthritis, a large number of studies may be necessary to verify this association in different populations and environmental factors." @default.
- W4229546755 created "2022-05-11" @default.
- W4229546755 creator A5019567095 @default.
- W4229546755 creator A5023290949 @default.
- W4229546755 creator A5041438685 @default.
- W4229546755 creator A5084740387 @default.
- W4229546755 creator A5085956552 @default.
- W4229546755 date "2019-10-23" @default.
- W4229546755 modified "2023-10-16" @default.
- W4229546755 title "Association between the polymorphism of MMP-1 gene with knee osteoarthritis risk: a meta-analysis" @default.
- W4229546755 doi "https://doi.org/10.21203/rs.2.16319/v1" @default.
- W4229546755 hasPublicationYear "2019" @default.
- W4229546755 type Work @default.
- W4229546755 citedByCount "0" @default.
- W4229546755 crossrefType "posted-content" @default.
- W4229546755 hasAuthorship W4229546755A5019567095 @default.
- W4229546755 hasAuthorship W4229546755A5023290949 @default.
- W4229546755 hasAuthorship W4229546755A5041438685 @default.
- W4229546755 hasAuthorship W4229546755A5084740387 @default.
- W4229546755 hasAuthorship W4229546755A5085956552 @default.
- W4229546755 hasBestOaLocation W42295467551 @default.
- W4229546755 hasConcept C104317684 @default.
- W4229546755 hasConcept C126322002 @default.
- W4229546755 hasConcept C142724271 @default.
- W4229546755 hasConcept C143998085 @default.
- W4229546755 hasConcept C149737253 @default.
- W4229546755 hasConcept C156957248 @default.
- W4229546755 hasConcept C180754005 @default.
- W4229546755 hasConcept C187960798 @default.
- W4229546755 hasConcept C204787440 @default.
- W4229546755 hasConcept C2776164576 @default.
- W4229546755 hasConcept C2776478404 @default.
- W4229546755 hasConcept C2992519594 @default.
- W4229546755 hasConcept C44249647 @default.
- W4229546755 hasConcept C54355233 @default.
- W4229546755 hasConcept C60644358 @default.
- W4229546755 hasConcept C71924100 @default.
- W4229546755 hasConcept C86803240 @default.
- W4229546755 hasConcept C95190672 @default.
- W4229546755 hasConceptScore W4229546755C104317684 @default.
- W4229546755 hasConceptScore W4229546755C126322002 @default.
- W4229546755 hasConceptScore W4229546755C142724271 @default.
- W4229546755 hasConceptScore W4229546755C143998085 @default.
- W4229546755 hasConceptScore W4229546755C149737253 @default.
- W4229546755 hasConceptScore W4229546755C156957248 @default.
- W4229546755 hasConceptScore W4229546755C180754005 @default.
- W4229546755 hasConceptScore W4229546755C187960798 @default.
- W4229546755 hasConceptScore W4229546755C204787440 @default.
- W4229546755 hasConceptScore W4229546755C2776164576 @default.
- W4229546755 hasConceptScore W4229546755C2776478404 @default.
- W4229546755 hasConceptScore W4229546755C2992519594 @default.
- W4229546755 hasConceptScore W4229546755C44249647 @default.
- W4229546755 hasConceptScore W4229546755C54355233 @default.
- W4229546755 hasConceptScore W4229546755C60644358 @default.
- W4229546755 hasConceptScore W4229546755C71924100 @default.
- W4229546755 hasConceptScore W4229546755C86803240 @default.
- W4229546755 hasConceptScore W4229546755C95190672 @default.
- W4229546755 hasLocation W42295467551 @default.
- W4229546755 hasLocation W42295467552 @default.
- W4229546755 hasLocation W42295467553 @default.
- W4229546755 hasOpenAccess W4229546755 @default.
- W4229546755 hasPrimaryLocation W42295467551 @default.
- W4229546755 hasRelatedWork W1984235851 @default.
- W4229546755 hasRelatedWork W2067140660 @default.
- W4229546755 hasRelatedWork W2127879534 @default.
- W4229546755 hasRelatedWork W2159313323 @default.
- W4229546755 hasRelatedWork W2411114647 @default.
- W4229546755 hasRelatedWork W2531767482 @default.
- W4229546755 hasRelatedWork W2587302229 @default.
- W4229546755 hasRelatedWork W2587435314 @default.
- W4229546755 hasRelatedWork W2918166950 @default.
- W4229546755 hasRelatedWork W4291824836 @default.
- W4229546755 isParatext "false" @default.
- W4229546755 isRetracted "false" @default.
- W4229546755 workType "article" @default.