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- W4229555110 abstract "Abstract Background: A growing number of researches supported that dietary fructose was associated with all the key features of metabolic syndrome (MetS). However, there was no related epidemiological studies among Chinese population despite that cases of MetS increased sharply. This study explores the relationship between dietary fructose and MetS among Chinese residents aged 45 and above. Methods: A total of 25528 participants (11574 males and 13954 females) were included in this nationwide representative cross-sectional study of China National Nutrition and Health Survey. Dietary fructose intake was assessed by 3-day 24-h dietary records. MetS was defined by the International Diabetes Federation and Chinese Diabetes Society criteria. Results: The consumption of dietary fructose was 11.6g/day for urban residents and 7.6g/day for rural residents. Fruits and vegetables as well as their products were the main food sources. There was no association between dietary fructose intake and the risk of MetS in both urban (P = 0.315) and rural residents (P = 0.230) after adjustment for confounding factors. Moreover, for urban residents participating physical activities, the risk of MetS in the fourth quartiles (OR: 0.67; 95%CI: 0.52-0.86) was reduced compared with the first quartile. In the sensitivity analysis, a significant reduction in the risk of MetS was also found in the fourth quartiles (OR, 95%CI: 0.67, 0.51-0.89; 0.63, 0.46-0.85; 0.74, 0.56-0.98) compared with the first quartile when excluding smokers, alcohol users, and underweight/obesity, respectively. And there was no association between dietary fructose intake and the risk of MetS after multivariate adjustment stratified by gender, smoking and alcohol use. Conclusions: Under the current dietary fructose intake status, there was no association between dietary fructose intake and the risk of MetS among Chinese residents aged 45 and above. Physical activity and relatively low fructose intake may have a beneficial synergistic effect on MetS." @default.
- W4229555110 created "2022-05-11" @default.
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- W4229555110 date "2020-10-01" @default.
- W4229555110 modified "2023-10-16" @default.
- W4229555110 title "Dietary Fructose and Risk of Metabolic Syndrome in Chinese Residents Aged 45 and above: Results from the China National Nutrition and Health Survey" @default.
- W4229555110 doi "https://doi.org/10.21203/rs.3.rs-41498/v2" @default.
- W4229555110 hasPublicationYear "2020" @default.
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