Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229601234> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4229601234 abstract "Abstract Background: Intravenous use of sufentanil can elicit cough. This study aimed to evaluate the inhibitory effect of pre-injection of a mall dose of remifentanil on sufentanil-induced cough during the induction of general anesthesia. Methods: This prospective, randomized, controlled trial was conducted from January 10, 2019 to March 01, 2019. A total of 100 patients undergoing elective surgery under general anesthesia were enrolled, and at last 84 patients were included and randomly allocated into two equal size groups (n=42): Patients in the Remifentanil group (R group) received an intravenous infusion of remifentanil 0.3 µg/kg (diluted to 2 ml) 1 minute before sufentanil injection; patients in the Control group (C group) received 2 ml of normal saline (NS) at the same time point. Injections of patients in both groups were completed within 5 seconds. Then, sufentanil 0.5 µg/kg was injected within 5 seconds and the number of coughs that occurred within 1 minute after sufentanil injection were recorded. One minute after sufentanil injection, etomidate 0.3 mg/kg and cisatracurium 0.15 mg/kg were given for general anesthesia induction irrespective of the presence or absence of cough. The mean arterial pressure (MAP) and heart rate (HR) at time points just before remifentanil pretreatment administration (T0), 3 minutes after administration (T1), 1 minute after intubation (T2), and 3 minutes after intubation (T3) were recorded. Results: The incidence of cough in patients in the R group and C group was 4.8% and 31%, respectively. Compared with group C, the incidence and severity of cough in group R was significantly lower (P <0.01). No significant differences were observed in MAP and HR at the time of general anesthesia induction between the two groups (P> 0.05). Conclusion: Pretreatment with a small dose of remifentanil effectively and safely reduced the incidence and severity of cough induced by sufentanil during anesthesia induction and can be used as an alternative treatment to inhibit coughing caused by sufentanil." @default.
- W4229601234 created "2022-05-11" @default.
- W4229601234 creator A5015737894 @default.
- W4229601234 creator A5035775574 @default.
- W4229601234 creator A5045923312 @default.
- W4229601234 date "2019-10-12" @default.
- W4229601234 modified "2023-09-23" @default.
- W4229601234 title "A small dose of remifentanil pretreatment suppresses sufentanil-induced cough during general anesthesia induction: a randomized, double-blind, placebo-controlled trial" @default.
- W4229601234 doi "https://doi.org/10.21203/rs.2.12883/v3" @default.
- W4229601234 hasPublicationYear "2019" @default.
- W4229601234 type Work @default.
- W4229601234 citedByCount "0" @default.
- W4229601234 crossrefType "posted-content" @default.
- W4229601234 hasAuthorship W4229601234A5015737894 @default.
- W4229601234 hasAuthorship W4229601234A5035775574 @default.
- W4229601234 hasAuthorship W4229601234A5045923312 @default.
- W4229601234 hasBestOaLocation W42296012341 @default.
- W4229601234 hasConcept C126322002 @default.
- W4229601234 hasConcept C141071460 @default.
- W4229601234 hasConcept C142724271 @default.
- W4229601234 hasConcept C168563851 @default.
- W4229601234 hasConcept C204787440 @default.
- W4229601234 hasConcept C27081682 @default.
- W4229601234 hasConcept C2776277131 @default.
- W4229601234 hasConcept C2777019824 @default.
- W4229601234 hasConcept C2777397205 @default.
- W4229601234 hasConcept C2777953023 @default.
- W4229601234 hasConcept C2778716859 @default.
- W4229601234 hasConcept C2778891214 @default.
- W4229601234 hasConcept C2779676917 @default.
- W4229601234 hasConcept C2781312054 @default.
- W4229601234 hasConcept C42219234 @default.
- W4229601234 hasConcept C71924100 @default.
- W4229601234 hasConcept C84393581 @default.
- W4229601234 hasConceptScore W4229601234C126322002 @default.
- W4229601234 hasConceptScore W4229601234C141071460 @default.
- W4229601234 hasConceptScore W4229601234C142724271 @default.
- W4229601234 hasConceptScore W4229601234C168563851 @default.
- W4229601234 hasConceptScore W4229601234C204787440 @default.
- W4229601234 hasConceptScore W4229601234C27081682 @default.
- W4229601234 hasConceptScore W4229601234C2776277131 @default.
- W4229601234 hasConceptScore W4229601234C2777019824 @default.
- W4229601234 hasConceptScore W4229601234C2777397205 @default.
- W4229601234 hasConceptScore W4229601234C2777953023 @default.
- W4229601234 hasConceptScore W4229601234C2778716859 @default.
- W4229601234 hasConceptScore W4229601234C2778891214 @default.
- W4229601234 hasConceptScore W4229601234C2779676917 @default.
- W4229601234 hasConceptScore W4229601234C2781312054 @default.
- W4229601234 hasConceptScore W4229601234C42219234 @default.
- W4229601234 hasConceptScore W4229601234C71924100 @default.
- W4229601234 hasConceptScore W4229601234C84393581 @default.
- W4229601234 hasLocation W42296012341 @default.
- W4229601234 hasLocation W42296012342 @default.
- W4229601234 hasLocation W42296012343 @default.
- W4229601234 hasOpenAccess W4229601234 @default.
- W4229601234 hasPrimaryLocation W42296012341 @default.
- W4229601234 hasRelatedWork W1980410714 @default.
- W4229601234 hasRelatedWork W2043588136 @default.
- W4229601234 hasRelatedWork W2167497342 @default.
- W4229601234 hasRelatedWork W2357988973 @default.
- W4229601234 hasRelatedWork W2411275361 @default.
- W4229601234 hasRelatedWork W3029307796 @default.
- W4229601234 hasRelatedWork W4229601234 @default.
- W4229601234 hasRelatedWork W4252591437 @default.
- W4229601234 hasRelatedWork W4318464900 @default.
- W4229601234 hasRelatedWork W3087863961 @default.
- W4229601234 isParatext "false" @default.
- W4229601234 isRetracted "false" @default.
- W4229601234 workType "article" @default.