FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4229670114> ?p ?o ?g. }

• W4229670114 endingPage "415" @default.
• W4229670114 startingPage "407" @default.
• W4229670114 abstract "Although normotensive cancer patients with acute pulmonary embolism (PE) are a heterogeneous population, most validated clinical prognostic scores classify these patients as high-risk individuals, which limits their usefulness in this setting. In this study, we aimed to identify readily available clinical predictors of overall 30-day and one-year mortality in normotensive cancer patients with PE. We performed a retrospective single-center study that included all normotensive cancer patients with PE diagnosed by multidetector computed tomography (MDCT) during emergency department stay between January 2010 and December 2011. Clinical, MDCT and laboratory variables were collected for all patients. A total of 69 patients were included. All-cause mortality was 28% and 55% at 30 days and one year of follow-up, respectively. Lower mean arterial pressure, higher lactate level and a higher Shock Index (SI) at hospital admission were associated with increased all-cause mortality at 30 days and one year of follow-up. The simplified Pulmonary Embolism Severity Index was not a predictor of short- or long-term mortality. An SI of ≥0.7 was found to be associated with lower event-free survival in both short- and long-term follow-up (hazard ratio 7.20 [95% CI, 1.66-31.21, p<0.01] and 3.51 [95% CI, 1.70-7.25, p<0.01], respectively). This is the first article reporting the value of the SI, a user-friendly and readily available clinical tool, as an independent and accurate predictor of 30-day and one-year all-cause mortality in normotensive cancer patients with symptomatic PE. Apesar de os doentes oncológicos (DO) normotensos com tromboembolia pulmonar aguda (TEP) constituírem uma população heterogénea, a maioria dos scores de prognóstico classifica estes doentes como sendo de alto risco, limitando a sua utilidade. O objetivo deste estudo foi a identificação de variáveis clínicas simples que constituíssem preditores de mortalidade aos 30 dias e a um ano em DO normotensos com TEP. Estudo retrospetivo, de centro único, que incluiu todos os DO normotensos com TEP diagnosticada por TC durante a permanência no SU, entre janeiro/2010 e dezembro/2011. Foram colhidas variáveis clínicas, radiológicas e laboratoriais. Sessenta e nove doentes foram incluídos. Uma pressão arterial média mais baixa, um valor de lactato mais alto e um valor de índice de choque (IC) mais elevado associaram-se a uma mortalidade de todas as causas mais elevada aos 30 dias e a um ano de follow-up. A taxa de mortalidade de todas as causas foi 28% e 55% aos 30 dias e a um ano de seguimento, respetivamente. O score de sPESI não foi um preditor de mortalidade a curto ou a longo prazo. Um valor de IC ≥ 0,7 associou-se a uma sobrevida mais baixa tanto a curto como a longo prazo (FC 7,20 IC 95%, 1,66 a 31,21, p < 0,01) e 3,51 (IC 95%, 1,70 a 7,25, p < 0,01), respetivamente. Este é o primeiro estudo que documenta o valor do IC como preditor independente e preciso da mortalidade aos 30 dias e a um ano de DO normotensos com TEP sintomática." @default.
• W4229670114 created "2022-05-11" @default.
• W4229670114 creator A5015632623 @default.
• W4229670114 creator A5025508354 @default.
• W4229670114 creator A5026173762 @default.
• W4229670114 creator A5027341254 @default.
• W4229670114 creator A5028313067 @default.
• W4229670114 creator A5052207293 @default.
• W4229670114 creator A5073664341 @default.
• W4229670114 creator A5078368361 @default.
• W4229670114 date "2019-06-01" @default.
• W4229670114 modified "2023-09-26" @default.
• W4229670114 title "Keeping prognostic assessment simple: The value of clinical features in normotensive cancer patients with pulmonary embolism" @default.
• W4229670114 doi "https://doi.org/10.1016/j.repce.2018.06.012" @default.
• W4229670114 hasPublicationYear "2019" @default.
• W4229670114 type Work @default.
• W4229670114 citedByCount "0" @default.
• W4229670114 crossrefType "journal-article" @default.
• W4229670114 hasAuthorship W4229670114A5015632623 @default.
• W4229670114 hasAuthorship W4229670114A5025508354 @default.
• W4229670114 hasAuthorship W4229670114A5026173762 @default.
• W4229670114 hasAuthorship W4229670114A5027341254 @default.
• W4229670114 hasAuthorship W4229670114A5028313067 @default.
• W4229670114 hasAuthorship W4229670114A5052207293 @default.
• W4229670114 hasAuthorship W4229670114A5073664341 @default.
• W4229670114 hasAuthorship W4229670114A5078368361 @default.
• W4229670114 hasBestOaLocation W42296701141 @default.
• W4229670114 hasConcept C118552586 @default.
• W4229670114 hasConcept C121608353 @default.
• W4229670114 hasConcept C126322002 @default.
• W4229670114 hasConcept C141071460 @default.
• W4229670114 hasConcept C164705383 @default.
• W4229670114 hasConcept C167135981 @default.
• W4229670114 hasConcept C207103383 @default.
• W4229670114 hasConcept C2776256026 @default.
• W4229670114 hasConcept C2776265017 @default.
• W4229670114 hasConcept C2780724011 @default.
• W4229670114 hasConcept C2908647359 @default.
• W4229670114 hasConcept C44249647 @default.
• W4229670114 hasConcept C71924100 @default.
• W4229670114 hasConcept C99454951 @default.
• W4229670114 hasConceptScore W4229670114C118552586 @default.
• W4229670114 hasConceptScore W4229670114C121608353 @default.
• W4229670114 hasConceptScore W4229670114C126322002 @default.
• W4229670114 hasConceptScore W4229670114C141071460 @default.
• W4229670114 hasConceptScore W4229670114C164705383 @default.
• W4229670114 hasConceptScore W4229670114C167135981 @default.
• W4229670114 hasConceptScore W4229670114C207103383 @default.
• W4229670114 hasConceptScore W4229670114C2776256026 @default.
• W4229670114 hasConceptScore W4229670114C2776265017 @default.
• W4229670114 hasConceptScore W4229670114C2780724011 @default.
• W4229670114 hasConceptScore W4229670114C2908647359 @default.
• W4229670114 hasConceptScore W4229670114C44249647 @default.
• W4229670114 hasConceptScore W4229670114C71924100 @default.
• W4229670114 hasConceptScore W4229670114C99454951 @default.
• W4229670114 hasIssue "6" @default.
• W4229670114 hasLocation W42296701141 @default.
• W4229670114 hasLocation W42296701142 @default.
• W4229670114 hasOpenAccess W4229670114 @default.
• W4229670114 hasPrimaryLocation W42296701141 @default.
• W4229670114 hasRelatedWork W2349671503 @default.
• W4229670114 hasRelatedWork W2398072084 @default.
• W4229670114 hasRelatedWork W2523006498 @default.
• W4229670114 hasRelatedWork W2761541723 @default.
• W4229670114 hasRelatedWork W2899925188 @default.
• W4229670114 hasRelatedWork W2902981377 @default.
• W4229670114 hasRelatedWork W2979375907 @default.
• W4229670114 hasRelatedWork W2980093723 @default.
• W4229670114 hasRelatedWork W3154944956 @default.
• W4229670114 hasRelatedWork W4321611656 @default.
• W4229670114 hasVolume "38" @default.
• W4229670114 isParatext "false" @default.
• W4229670114 isRetracted "false" @default.
• W4229670114 workType "article" @default.