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- W4229694486 abstract "In order to test the hypothesis that there is a general correlation between mutagenesis and the initiation stage of carcinogenesis, some of the recently developed mutagens, whose mechanisms of interaction with DNA are partly understood, were tested for initiation of skin carcinogenesis in mice. Substances used were :1.(a) Aminoacridines: acridine yellow and acridine orange.2.(b) DNA base analogue: 5-bromodeoxyuridine, 5-iododeoxyuridine, 2-amino-purine and 2,6-diaminopurine.3.(c) The weak β emitter, 3H, in the form of tritiated thymidine.These compounds failed to induce skin tumours when the treated animals were subsequently painted with croton oil. Neither did they significantly increase the spontaneous lung adenoma incidence in these mice." @default.
- W4229694486 created "2022-05-11" @default.
- W4229694486 date "2000-05-01" @default.
- W4229694486 modified "2023-10-14" @default.
- W4229694486 title "Opportunities for conversion of powertrain parts from cast irons to PM" @default.
- W4229694486 doi "https://doi.org/10.1016/s0026-0657(00)88881-5" @default.
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